This study aims to investigate the possible role of circulating microRNA-142-3p (miR-142-3p) in the
development of graves disease (GD) and its association with the antibody directed against thyroid
stimulating hormone receptor (TSHR-Ab) production in patients with GD. Forty patients with positive
TSHR-Ab enrolled in this study were divided ,based on treatment, into (22 untreated (newly diagnosed) and
18 treated patients) and based on family history (30 with positive family history and 10 with negative family
history). In addition to forty healthy subjects with sex and age matching as a control group. The expression
level of circulating miR-142-3p was determined by two steps reverse transcription polymerase c

Abstract Background: Acute myeloid leukemia (AML) results from sequential genetic alterations in a normal hematopoietic stem cell or its progenitors giving rise to an autonomous clone that dominates the bone marrow leading to marrow failure. MicroRNAs are short non-coding nucleic acid sequences that regulate post-transcriptional gene expression by base-pairing with their target mRNAs. MiRNAs can be secreted into extracellular fluids and carried to target cells by vesicles or bound to proteins. Intracellular and circulating miRNAs are believed to be useful markers in the diagnosis, prognosis, and treatment of various cancers. Practically, circulating miRNAs are more stable at room temperatures and extreme conditions. Purpose: This study aim

Coagulation is the most important process in drinking water treatment. Alum coagulant increases the aluminum residuals, which have been linked in many studies to Alzheimer's disease. Therefore, it is very important to use it with the very optimal dose. In this paper, four sets of experiments were done to determine the relationship between raw water characteristics: turbidity, pH, alkalinity, temperature, and optimum doses of alum [   .14 O] to form a mathematical equation that could replace the need for jar test experiments. The experiments were performed under different conditions and under different seasonal circumstances. The optimal dose in every set was determined, and used to build a gene expression model (GEP). The models were co

In this paper, we obtain a complete characterization for the norm and the minimum norm attainment sets of bounded linear operators on a real Banach spaces at a vector in the unit sphere, using approximate 𝜖-Birkhoff-James orthogonality techniques. As an application of the results, we obtained a useful characterization of
bounded linear operators on a real Banach spaces. Also, using approximate 𝜖-Birkhoff -James orthogonality proved that a Banach space is a reflexive if and only if for any closed hyperspace of , there exists a rank one linear operator such that , for some vectors in and such that 𝜖 .Mathematics subject classification (2010): 46B20, 46B04, 47L05.

Highly plastic soils exhibit unfavorited properties upon saturation, which produce different defects in engineering structures. Attempts were made by researchers to proffer solutions to these defects by experimenting in practical ways. This included various materials that could possibly improve the soil engineering properties and reduce environmental hazards. This paper investigates the strength behavior of highly plastic clay stabilized with brick dust. The brick dust contents were 10%, 20%, and 30% by dry weight of soil. A series of linear shrinkage and unconfined compression tests were carried out to study the effect of brick dust on the quantitative amount of shrinkage experienced by highly plastic clay and the undra

Recently there has been an urgent need to identify the ages from their personal pictures and to be used in the field of security of personal and biometric, interaction between human and computer, security of information, law enforcement. However, in spite of advances in age estimation, it stills a difficult problem. This is because the face old age process is determined not only by radical factors, e.g. genetic factors, but also by external factors, e.g. lifestyle, expression, and environment. This paper utilized machine learning technique to intelligent age estimation from facial images using support vector machine (SVM) on FG_NET dataset. The proposed work consists of three phases: the first phase is image preprocessing include four st

The nonlinear optical properties for polymeric (PMMA) doping with dye Rhodmine (R3Go) has been studied .The samples are prepared by normal polymerization method with concentrations of 5x10^-5mol/l and a thickness of 272.5µm.

                         Plasma effect was studied on samples prepared before and after exposure to the Nd: YAG laser for three times 5, 10 and 15 minutes. Z-Scan technique is used to determine the nonlinear optical properties such as; refractive index (n₂) and the coefficient of nonlinear absorption (β). It was found that the nonlinear properties is change by increasi

Trimmed Linear moments (TL-moments) are natural generalization of L-moments that do not require the mean of the underlying distribution to exist. It is known that the sample TL-moments is unbiased estimators to corresponding population TL-moment. Since different choices for the amount of trimming give different values of the estimators it is important to choose the estimator that has minimum mean squares error than others. Therefore, we derive an optimal choice for the amount of trimming from known distributions based on the minimum errors between the estimators. Moreover, we study simulation-based approach to choose an optimal amount of trimming and maximum like hood method by computing the estimators and mean squares error for range of

Twitter is becoming an increasingly popular platform used by financial analysts to monitor and forecast financial markets. In this paper we investigate the impact of the sentiments expressed in Twitter on the subsequent market movement, specifically the bitcoin exchange rate. This study is divided into two phases, the first phase is sentiment analysis, and the second phase is correlation and regression. We analyzed tweets associated with the Bitcoin in order to determine if the user’s sentiment contained within those tweets reflects the exchange rate of the currency. The sentiment of users over a 2-month period is classified as having a positive or negative sentiment of the digital currency using the proposed CNN-LSTM

تستند أغلب الطرائق الحصينة على فكرة التنازل عن جانب معين مقابل تقوية جانب آخر من خلال عدة أساليب أما آليات الذكاء الصناعي تحاول عمل موازنة بين الضعف والقوة للوصول إلى أفضل الحلول بأسلوب بحث عشوائي . في هذا البحث تم تقديم فكرة جديدة لتحسين مقدرات معلمات نماذج المعادلات الآنية الخطية الناتجة من طريقة المتغيرات المساعدة حسب طريقة جاكنايف Jackknife Instrumental Variable Estimation(JIVE) وذل