Background: This study compared in vitro the marginal adaptation of three different, low shrink, direct posterior composites Filtek™ P60 (packable composite), Filtek™ P90 (Silorane-based composite) and Sonic fill™ (nanohybrid composite) at three different composite/enamel interface regions (occlusal, proximal and gingival regions) of a standardized Class II MO cavity after thermal changes and mechanical load cycling by scanning electron microscopy. Materials and methods:Thirty six sound human maxillary first premolars of approximately comparable sizes were divided into three main groups of (12 teeth) in each according to the type of restorative material that was used: group (A) the teeth were restored with Filtek™ P60 and single bond™ Universal adhesive using horizontal incremental technique, group (B)the teeth were restored with Filtek™ P90 and P90 system adhesive using horizontal incremental technique and group (C) the teeth were restored with Sonic fill™ composite and single bond™ Universal adhesive using bulk technique.After specimens were stored in distilled water at 37°C for 7 days, all specimens were subjected to thermocycling at (5° to 55 °C), then submitted to mechanical load cycling (intermittent axial force of 49N and a total of 50.000 cycles). The specimens were observed under scanning electron microscope at (2000 X) to measure marginal gap width (the distance between the dental wall and the restoration) at occlusal, proximal and gingival regions in micrometer using Tescan software, version 3.5. Data were analyzed statistically by one way ANOVA test and least significant difference tests. Results:The results showed that the silorane-based posterior composite (Filtek™ P90) showed significantly the least marginal gap width at the occlusal, proximal and gingival regions after the application of thermal changes and mechanical load cycling in comparison to the two methacrylate-based posterior composite Filtek™ P60 (packable) and the Sonic fill™ (nano-hybrid). Sonic fill™ bulk fill composite that relied on the vibration concept to lower the viscosity of high filler loaded composite material showed significantly lesser marginal gaps width at occlusal, proximal and gingival composite/enamel interface regions in comparison with Filtek™ P60 (packable composite) using horizontal incremental technique. The silorane-based composite (Filtek™ P90) showed non-significant difference in marginal gaps width at the three different regions. While, both methacrylate based Filtek™ P60 and Sonic fill™ composite showed significantly lesser marginal gap width at the occlusal region in comparison with gingival regions. Conclusion: None of the low-shrinkage composite restorative materials tested in this study totally prevented micro-gap formation at composite/enamel interfaces of Class II MO cavity.
The dynamic development of computer and software technology in recent years was accompanied by the expansion and widespread implementation of artificial intelligence (AI) based methods in many aspects of human life. A prominent field where rapid progress was observed are high‐throughput methods in biology that generate big amounts of data that need to be processed and analyzed. Therefore, AI methods are more and more applied in the biomedical field, among others for RNA‐protein binding sites prediction, DNA sequence function prediction, protein‐protein interaction prediction, or biomedical image classification. Stem cells are widely used in biomedical research, e.g., leukemia or other disease studies. Our proposed approach of
... Show MoreIn this research, annealed nanostructured ZnO catalyst water putrefaction system was built using sun light and different wavelength lasers as stimulating light sources to enhance photocatalytic degradation activity of methylene blue (MB) dye as a model based on interfacial charges transfer. The structural, crystallite size, morphological, particle size, optical properties and degradation ability of annealed nanostructured ZnO were characterized by X-Ray Diffraction (XRD), Atomic Force Microscopy (AFM) and UV-VIS Spectrometer, respectively. XRD results demonstrated a pure crystalline hexagonal wurtzite with crystalline size equal to 23 nm. From AFM results, the average particle size was 79.25nm. All MB samples and MB with annealed nanostr
... Show MoreIn this paper, an intelligent tracking control system of both single- and double-axis Piezoelectric Micropositioner stage is designed using Genetic Algorithms (GAs) method for the optimal Proportional-Integral-Derivative (PID) controller tuning parameters. The (GA)-based PID control design approach is a methodology to tune a (PID) controller in an optimal control sense with respect to specified objective function. By using the (GA)-based PID control approach, the high-performance trajectory tracking responses of the Piezoelectric Micropositioner stage can be obtained. The (GA) code was built and the simulation results were obtained using MATLAB environment. The Piezoelectric Micropositioner simulation model with th
... Show MoreImproved oral bioavailability of lipophilic substances can be achieved using self-emulsifying drug delivery systems. However, because the properties of self-emulsifying are greatly influenced by surfactant amount and type, type of oil used, droplet size, charge, cosolvents, and physiological variables, the synthesis of self-emulsifying is highly complex; consequently, only a small number of excipient self-emulsifying formulations has been developed so far for clinical use. This study reports a highly effective procedure for developing self-emulsifying formulations using a novel approach based on the hydrophilic-lipophilic difference theory. Microemulsion characteristics, such as the constituents and amounts of oil and surfactant electrolyte
... Show MoreNews headlines are key elements in spreading news. They are unique texts written in a special language which enables readers understand the overall nature and importance of the topic. However, this special language causes difficulty for readers in understanding the headline. To illuminate this difficulty, it is argued that a pragmatic analysis from a speech act theory perspective is a plausible tool for a headline analysis. The main objective of the study is to pragmatically analyze the most frequently employed types of speech acts in the news headlines covering COVID-19 in Aljazeera English website. To this end, Bach and Harnish's (1979) Taxonomy of Speech Acts has been adopted to analyze the data. Thirty headlines have been collected f
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