Background: ?-L-Fucose is a methyl pentose sugar, had the ability to kill bacteria, controlling infection and normalize immune function. The objective of this study is to determine the effect of sulcular injection of fucose on rabbits periodontium , throughout measuring the level of some proinflammatory cytokine ; interlukine 1beta ( IL-1beta) and tumor necrosis factor ( TNF-alpha) in sera of rabbits before fucose injection and at 3 days after fucose injection. Materials and Methods: The study was carried on using ( 20 ) male rabbits of the same species weighted (1-1.5 kg ) , the blood samples were collected from hearts of 20 rabbits before fucose injection and consider as( non injected group) , and after 3 days of fucose injection and consider as (fucose injected group) and analyzed for determination of the concentration of IL-1ß and TNF-?. Results: The results showed a highly significant decrease in the mean concentration of TNF-? in sera of fucose injected group(19.05± 1.166) pg ?ml when compared to its mean concentration in non injected group (27.25±7.371) pg ?ml ,also a highly significant decrease in the mean concentration of IL-1ß in sera of fucose injected group(34.19 ± 3.1)pg ?ml as compared to its mean concentration in sera of non injected group (38.86 ±4.565)pg?ml. Conclusion: both proinflammatory cytokines were influenced and inhibited by local fucose injection
Cytokines are polypeptides with several functions that are produced by a variety of bodily cells. They are clinically significant for illness diagnosis, treatment, and prevention. Interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) are the most important cytokines for cell division and proliferation. Vascular endothelial growth factor (VEGF) is produced in excess in mesenchymal, epithelial, and especially in tumor cells. In this study the serum levels of IL-6, TNF-α and VEGF were detected for 41 colorectal cancer patients and 41 healthy control group at Nanakaly Hospital by comparing their serum concentrations for patients paining from colorectal carcinoma (CRC) with those of the control subjects. The result shows a s
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Background: Orthodontic tooth movement is characterized by tissue reactions, which consist of an inflammatory response in periodontal ligament and followed by bone remodeling in the periodontium depending on the forces applied. These processes trigger the secretion of various proteins and enzymes into the saliva.The purpose of this study was to evaluate the activity of alkaline phosphatase (ALP) in saliva during orthodontic tooth movement using different magnitude of continuous orthodontic forces. Materials and Methods: Thirty orthodontic patients (12 males and 18 females) aged 17-23 years with class II division I malocclusion all requiring bilateral maxillary first premolar extractions were randomly divided into three groups according to t
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In this study, only four isolates produce CNF1 from 76 isolatesof uropathogenic Escherichia coli.cnf1 gene was detected by using PCR technique, while cytotoxic necrotizing factor 1(CNF1) was determined by Immunoblotting assay.
This study was conducted to determine the relationship between two most common diseases in Iraqis patients , which are Diabetic mellitus (DM) and Rheumatoid Arthritis (RA); seeking rheumatoid factor in hyperglycemic sera. The results revealed that ; 62.5% of hyperglycemic (HG) patients had positive rheumatoid factor (RF) . No difference in number between both gender of HG patients (20 males and 20 females ) , RF reaction was nearly similar in males and females of HG patients ( 12 &13 respectively ) . Only 40% out of patient controls had positive RF . None of the apparently healthy subjects had positive RF .
Alpha shape theory for 3D visualization and volumetric measurement of brain tumor progression using magnetic resonance images
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Back ground: Gastrointestinal Stromal Tumors (GISTs), although are rare, are the most common mesenchymal tumors of the digestive system. Vascular endothelial growth factor(VEGF) is associated with the malignant potential of several types of carcinomas.
Patients, material, and methods: This is a retrospective study including thirty two randomly selected cases of GISTs collected from the pathology laboratory of the gastroenterology and hepatology teaching hospital and from private laboratories from the period January 2010 to December 2013. VEGF immunohistochemical marker was applied to the tumor tissue sections to evaluate its expression and to correlate it with other parameters.Objectives<
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This study was conducted in the specialized center of endocrinology and diabetic (AlKindy hospital from June 2004 to April 2005). Sera of 80 women (include 40 diagnosed Hyperprolactinemia (HPro) and 40 healthy women as control) were used to estimate some biochemical parameters which include prolactin (PRL),total fucose (TF), total protein (TP) and protein bound fucose (PBF), and protein bound hexose (PBHex), also TP TF , TP PBF and TP PBHex ratios. A significant elevation in TP and PBHex, in sera of HPro patients compared to control was found while PBHex/TP ratio showed a slight non significant increase in sera of patients compared to control. On the other hand a significant decrease in TF, TF/TP and PBF/TP in ser
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