Background: Human colorectal carcinogenesis is a complex, multistep and multigenetic process. Matrix metalloproteinase-2 and cyclooxygenase-2 are key enzyme in degradation of extracellular material, are over expressed in several epithelia like colorectal adenocarcinoma.
Objectives: This study was designed to detect the expression of matrix metalloproteinase-2 and cyclooxygenase-2 in patients with colorectal carcinoma and their correlation with age, gender, tumor grade and presence or absence of muscle invasion.
Materials and methods: Immunohistochemical staining of MMP-2 and COX-2 was determined in 40 tissue samples from colorectal patients, from teaching laboratories in Baghdad medical city. In addition twelve apparently normal colorectal autopsies were used as a control group.
Results: The expression of matrix metalloproteinase-2 was detected in 30 of 40 colorectal cancer cases (75%) while cyclooxygenase-2 was detected in 31 0f 40 colorectal cancer cases (77.5%). All normal colorectal specimens showed negative results. The incidence of both of them was higher for grade II than those in earlier grade.
Conclusion: Cancer cells to have a more aggressive behavior may show an up regulation of tumor cell derived matrix metalloproteinase-2 and cyclooxygenase-2.
أستأثر الاتجاه نحو مفهوم العولمة اهتمام العديد من الباحثين والدارسين رغم حداثته نسبياً ، فهي كظاهرة ما زالت في طور التكوين ، الا انها غزت كل المجالات وتناولها الجميع بمختلف اهتماماتهم فتصدى للحديث عنها المثقفون والسياسيون والاجتماعيون والاقتصاديون الا انه في الوقت نفسه الكتابات والبحوث المعمقة في هذا الجانب ما زالت قليلة ويظل بذلك هذا المفهوم من اكثر المفاهيم المتداولة جاذبية واثارة للجدل عند العام
... Show MoreThe childhood period includes nursery period is the most period that the child wants to discover and knowledge and that we see it in daily and normal activity that he does it. And after creating the science aspects and growth it by children and that is one of goals the Education and this goal is requested a style education includes a corrective scientific aspects and creating them and getting them by experience that getting it by visits many places of nurseries and meeting some of teachers and search about the program working and application it and notes a problem that summarized that is not found a science program used by teacher to teach the science aspects for children that realized her goals and needs to gro
... Show MoreThe aims of the research have been determined as:
1- Creative personality according to the students of the Fine Arts Institute.
- 2- Indication of variances in the creative personality , the manner depending upon the variables of person (males, females).
- The research sample consisted of (400) students of Fine Arts Institute for (Boys and Girls)/ Baghdad
- The Scientific Research concluded the following:
- 1-The students of the Fine Arts Institute have a high from the creative personality .
- 2- There is a different in the creative personality according to the &
Sought Current search to know the concepts of modern literature theoretical educational, psychological and social are thinking double and tolerance and the definition of them in the theoretical frameworks of religious, social and psychological to clarify their role in life in general and in university life private and to understand their respective roles in the promotion of the other, and research has included a chapter first to identify the importance and the objectives and terms Search in detail, and a chapter of a second frameworks and theoretical literature of concepts ranging from religious heritage in Islam and other religions, especially the concept of tolerance, then look at social, psy
... Show MoreHere’s a research about epistemology including answer for the most essential questions those which associate with human knowledge, It’s the sources of knowledge and it's pathways depending on showing and criticizing the empirical doctrine represented by John Locke, David Hume and others, not only the empirical doctrine but also the contemporary scientism doctrine the one that characterized by science abilities glorification which is represented by contemporary scientists such as: Stephen Hawking and some few others .The common points between both of the doctrines (scientism and empirical) will be clarified for the reader and also the uncommon ones, ultimately, we will briefly spotlight on the basics of the Islamic vision about knowle
... Show MoreThe current research aimed to identify:
- Social perception among university students.
- Differences in social Perception according to the variables:
Gander` (male, female) b- theme (scientific, humanitarian(
- Moral judgments among university students.
- Differences in moral judgments according to two variables:
A-type (male, female) b- theme (scientific, humanitarian)
- Emotional tranquility among university students.
- Differences in emotional tranquility according to two variables:
A-type (male, female) b- theme (scientific, humanitarian)
- Contributio
يرى الباحثون في علم النفس إن السنوات الأولى من حياة الطفل هي من أهم السنوات في تكوين شخصيته وتوجيهها وتنشئتها النشأة التي تبنى عليها أصولها من خلال مراحل النمو التالية. ( الطحان، 1987، ص 17)
إن من أهم أنواع السلوك التي يتعلمها الطفل في بداية السنة الأولى من حياته هي الاستجابات الاجتماعية للناس نتيجة تفاعله مع أمه وان هذه الاستجابات للام أو لمن ينوب عنها يتسع مجالها كل
... Show Moreأولاً: مشكلة البحث:
على الرغم من أن كل شخص هو كائن متفرد بحد ذاته ، إلا أن هناك تشابهات مشتركة بين كثير من الناس ، وتشكل هذه التشابهات أنماطآ شخصية يهدف علم النفس إلى دراستها وفهمها.
وقد حاول علماء النفس والمنظرون في مجال الشخصية بناء أنظمة نظرية لتغطية التباين الواسع بين الأفراد في السلوك ضمن المواقف المختلفة. وهدفت جهودهم إلى فهم الدافعية البشرية ، والسلوك عن طريق عملية النمو
... Show MoreThe research aimed at revealing the relation between Independency and The
Concept of self of The Children Who have Working and not Working Mothers,
and to accomplish the aim of the research, the researcher built two measures, the
first was to measure Independency and the second was to measure Concept of self
. after Appling them on the sample of the research which consists of Children
(males and females ) Working and not Working Mothers . the following result
appeared :
The difference in the degrees of independency was in favor of the males
who have working mothers and the females who have not Working Mothers .
The difference in the degrees of Concept of self was in favor of the males
who have work
The objective of this research to identify the level of job satisfaction among lecturers Iraqi universities on the Law of University Service has determined the research community in the teaching staff or lecturers University (Baghdad, Mustansiriya, Technology, Al-Nahrean) were selected the same of them with a volume of (400) teaching (male and female) to complete the research has been prepared to identify composed of (49) items distributed on four axes and Search Results indicated that the level of job satisfaction among the teaching Iraqi university courses on the law of service is characterized by the presence of positive and job satisfaction and the law in general.