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The expression of Matrix metalloproteinase-2 and cyclooxygenase-2 by immunohistochemistry in patients with colorectal carcinoma

Background: Human colorectal carcinogenesis is a complex, multistep and multigenetic process. Matrix metalloproteinase-2 and cyclooxygenase-2 are key enzyme in degradation of extracellular material, are over expressed in several epithelia like colorectal adenocarcinoma.
Objectives: This study was designed to detect the expression of matrix metalloproteinase-2 and cyclooxygenase-2 in patients with colorectal carcinoma and their correlation with age, gender, tumor grade and presence or absence of muscle invasion.
Materials and methods: Immunohistochemical staining of MMP-2 and COX-2 was determined in 40 tissue samples from colorectal patients, from teaching laboratories in Baghdad medical city. In addition twelve apparently normal colorectal autopsies were used as a control group.
Results: The expression of matrix metalloproteinase-2 was detected in 30 of 40 colorectal cancer cases (75%) while cyclooxygenase-2 was detected in 31 0f 40 colorectal cancer cases (77.5%). All normal colorectal specimens showed negative results. The incidence of both of them was higher for grade II than those in earlier grade.
Conclusion: Cancer cells to have a more aggressive behavior may show an up regulation of tumor cell derived matrix metalloproteinase-2 and cyclooxygenase-2.

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Publication Date
Mon Jun 28 2021
Journal Name
Journal Of The College Of Education For Women
The Effect of Natural Factors on the Cultivation and Production of Sesame Crop in Al-Qadisiyah Governorate: كوثر ناصر عباس

Sesame crop, one of the very important oily, industrial, and summer crops that is economically important, has been investigated. The plantation and production of this crop has been studied in Al-Qadisiyah governorate during 2003-218. This is because this governorate is well-known by sesame plantation. Such a study helps to know the geographical distribution of sesame agricultural season in 2017-2018, and explore the most important natural factors that affect its plantation. Different research approaches have been adopted based on that facts that need to be met. A field study approach has been used in studying sesame crop descriptively and conceptually, shedding light on its nutritional and economic importance. Moreover, a descriptive com

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Publication Date
Sun Dec 01 2019
Journal Name
Journal Of Accounting And Financial Studies ( Jafs )
Evaluation the Emotional Intelligence of Administrative and Audit leaderships in the Federal Board of Supreme Audit to achieve audit Effectiveness

The Psychologists have noticed, not long ago, that the man’s success and happiness in life do not only depend on his degree and education, which express on his mental intelligence but also they need another kind of intelligence called emotional intelligence. The research aims at identifying the emotional intelligence level of the top and administrative leaderships in the Federal Board of Supreme Audit by evaluating their emotional intelligence when the administrative and audit leaderships face emotional interactions by dealing with administrative and audit stuffs in the Board. The research problem is focused on the following question “Is the emotional intelligence of the top and administrative leaderships in the Fede

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Publication Date
Tue Jun 01 2021
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Notes on the ecology and distribution of the annual fern Anogramma leptophylla (L.) Link. (Pteridaceae) in Northern districts of Iraq

The study involved the description of the environmental characters and distribution of Anogramma  leptophylla  (Annual  Maidenhair fern)  in Erbil and Garmian districts during May- 2017 in Kurdistan of Iraq. The geographical distribution of the taxa was recorded in Bani Bee region for the first time within the Garmian district but it was recorded before in the Zar Gali region within the Erbil district. The climatic characters of the studied site in Erbil district were: moist, cold and the elevation was up to 560 m above sea level with sandy clay soil texture whereas in the Garmian district: dry, hot, and the elevation was only 330 m  above sea level with sandy stone soil. Plant up to 13 cm long, megaphyl

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Publication Date
Fri Dec 08 2023
Journal Name
Iraqi Journal Of Science
Use GIS to Draw the concentrations Maps of the Heavy Elements and Boron of Groundwater In Southwest Karbala Governorate/Iraq

The area of study is located at southern east of Karbala governorate, in basin of Dibdiba formation (upper Miocene-Pliocene), between longitudes (43ο 57' 34.2" & 44ο 09' 49.2ʺ) and latitudes (32ο 23' 16.4" & 32ο 36' 03.2"), this area about ( 336 ) km2. It is consists the geochemical and hydrochemical studies of heavy elements (Co, Ni, Mn, Cd, Pb, Zn, Fe) and (B+3) and measure the concentration of elements from samples of groundwater of 16 wells. After data collection from the analysis of the samples of water we are saving the results on the computer, with GIS software techniques, and draw different maps which represent the zones of the distribution of concentrations the metals. From the maps we are seen the zone of higher co

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Publication Date
Fri Mar 01 2019
Journal Name
Journal Of Accounting And Financial Studies ( Jafs )
Evaluation of accounting procedures for joint arrangements in the Iraqi environment and their reflection on the quality of financial reporting

The research aims to assess the local accounting procedures related in one of developments that have taken place, and largely on the structure of the Iraqi economic activity. But a partnership between the (public and private sector), or one of the types of joint arrangements, and through the use of the analytical method and extrapolate the reality of the accounting treatments in Company research sample. Research found to a number of conclusions that the unified accounting system applied in the economic units that deal with contracting joint arrangements formula suffers from obvious shortcomings, and reflected the common arrangements suffer from obvious shortcomings. and reflected on the quality of financial reporting, and the urgent need

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Publication Date
Wed Aug 30 2023
Journal Name
Al-kindy College Medical Journal
The Impact of using the Internet and Social Media on Sleep in a group of Secondary School Students from Baghdad

Background: Insufficient sleep due to excessive media use is linked to decrease physical activity, poor nutrition, obesity, and decreased overall health-related quality of life.

Objectives: To assess the effect of using the internet and social media on the sleep of 4th-stage secondary school students.

Subjects and Methods: Cross-sectional study with the analytic element; for 500 secondary school students, obtained by choosing two schools randomly from each of the six educational directorates, by using a structured questionnaire.

Result: Secondary scho

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Publication Date
Wed Mar 30 2011
Journal Name
التربية نبض حي وفعل إنساني متجدد / المؤتمرالعلمي الثالث عشركلية التربية الأساسية / الجامعة المستنصرية
Publication Date
Sat Mar 26 2022
Journal Name
مجلة نسق
أنماط الشخصية الإنيكرام (مركز الغريزة) لدى طلبة قسم التربية الخاصة

استهدف البحث الحالي تعرف أنماط الشخصية الإنيكرام السائدة ضمن مركز الغريزة لدى طلبة قسم التربية الخاصة، وكذلك تعرف أنماط الشخصية الإنيكرام السائدة ضمن مركز الغريزة لدى طلبة قسم التربية الخاصة وفقاً لمتغير النوع (ذكور، إناث)، ولتحقيق هذه الأهداف تم اعتماد الصورة المختصرة لمقياس أنماط الشخصية الإنيكرام المُعد من قبل (ريسو-هيودسن، 1995)، ترجمة (الياسري، 2004)، (تقنين: السلطاني، 2007)، وقد تم التحقق من الخصائص السيكومت

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Publication Date
Sun Mar 10 2019
Journal Name
مجلة علوم الانسان والمجتمع
قياس الشخصية الاستغلالية لدى طلبة الجامعة في ضوء بعض المتغيرات

دف البحث إلى قياس الشخصية الاستغلالية لدى طلبة الجامعة على وفق متغيرات: الجنس والتخصص والمرحلة الدراسية ، تكونت عينة البحث من (200) طالباً وطالبة من طلبة جامعة بغداد، قامت الباحثة ببناء مقياس الشخصية الاستغلالية وبعد تطبيقه على العينة وتحليل البيانات بالوسائل الاحصائية المناسبة ، اظهرت نتائج البحث عن شيوع الشخصية الاستغلالية لدى الطلبة ، وان الذكور لديهم شخصية استغلالية اكثر موازنة بالاناث كما اظهرت نتائج ا

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Publication Date
Sun Jan 01 2017
Journal Name
كلية التربية للبنات
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