Back ground: nasopharyngeal carcinoma is rare in Iraq and the treatment of this tumor is usually by radiotherapy and chemotherapy.
Objectives: this study was conducted to estimate the effect of neoadjuvant chemotherapy in Iraqi patients with nasopharyngeal carcinoma
Patients and methods: This study included sixty patients already diagnosed with nasopharyngeal tumors who attended the department of oncology in Baghdad teaching hospital during the period from January 2009 to December 2010,50 patients of them were treated by using combination chemotherapy in the form of Paclitaxel,5Flurouracil and cisplatinol for 4 courses prior to radiotherapy. Neoadjuvant chemotherapy was given due to advanced stage at presentation and due to long waiting list for radiotherapy which takes at least 6 months.10 patients were excluded from the study due to different reasons.
Results: About half of the patients had partial response to neoadjuvant chemotherapy,only 8 patients (16%) had complete response, 12 patients (24%) did not show any response and 5 patients (10%) have progressive disease during the course of neo adjuvant chemotherapy.
Conclusion: Neoadjuvant chemotherapy is beneficial in the management of Nasopharyngeal Cancer regarding local control and overall response rate.
The expression of MUC5AC has been associated with the loss of the differentiation, TNM system, and nodal metastasis, in many cancers including gastric carcinoma (GC).Objective: To evaluate whether the MUC5AC could be used as a predictor in patients with GC and to assess the correlation between the expression of MUC5AC& the clinicpathological parameters as age, sex, histopathological subtypes, grade and stage of the tumor. This is a retrospective study conducted on 60 randomly selected patients (30 normal vs 30 GC), at the Pathology Department of the Gastroenterology and Hepatology Teaching Hospital&some private laboratories. They were collected and diagnosed during the period 2014-2018. Histological sections were stained wi
... Show MoreBackground: Squamous cell carcinoma (SCC) is the most prevalent malignant neoplasm of the oral cavity that exhibits certain histological variations. Verrucous carcinoma (VC) is an uncommon exophytic low-grade well-differentiated variant of SCC. Cellular differentiation and morphology play important roles in cell functions and maintenance of structural integrity .As the cancer is a malignant process in which disorder of the cell growth and behavior occurs, such changes may differ in different tumor types and within different grades of the same tumor. Materials and Methods:Forty two formalin – fixed, paraffin – embedded tissue blocks were included in this study (30 blocks were diagnosed as OSCC and 12 blocks were diagnosed as OV
... Show MoreThe research studies the synthetic sculpture techniques in the outputs of the students of the department of art education in terms of the shape, texture, content and technique, and employing this style by the students of the department of art education on the college of fine arts, university of Diyala. The research consists of four chapters: the first chapter: the research problem summarized by looking for the synthetic sculpture and its importance in the treatment the industrial wastes in our social life, according to modern synthetic techniques, in the American and European sculpture. This technique has been employed in more than one contemporary artistic direction and style.
This study is considered important for the students of t
Objective(s): to assess the effectiveness of educational program on nurses' knowledge concerning the side
effects of chemotherapy among children with leukemia.
Methodology: A descriptive analytic (quasi – experimental) design study was carried out at Baghdad City from
2
nd of October to 27th of June 2015. Non-probability sample of (35) male and female nurses was selected from
the Oncology Wards in Children Welfare, Child's Central and Baghdad Teaching Hospital. The study
instruments consisted of two major parts to meet the purposes of study. The first part is related to nurses'
demographic characteristics and the second part (four domains) is related to nurses' knowledge concerning the
side effects of chemothera
Background: Staging of primary carcinoma of the larynx play an important role in surgical management of the disease .This staging depends on the clinical finding and radiological examination , supported by pathological assessment of the excised tumor
Objectives: To evaluate the accuracy of clinical and radiological staging Patients’ and methods: Forty-two patients with laryngeal carcinoma were admitted to the ENT Department during the period from June 2009 through October 2010. Each patient was staged by clinical examination and computed tomography. Evaluation of the results compared to the final diagnosis of staging , based on the pathological staging of specimens of patients who underwent total l
Introduction: With the advent of era of targeted cancer therapy, the serious side effects of chemoradiotherapy have been minimised. Considering the success story of anti-HER2/neu drugs in breast cancer oncology, the present study was conducted. The study evaluates the immunohistochemical expression of HER2/neu in endometrioid cancer among Iraqi patients. Aim: To assess the immunohistochemical expression of HER2/neu in endometrioid carcinoma of uterus and to find the relationship of this expression with FIGO stage and grade and with patient age. Materials and Methods: In this cross sectional study, formalin-fixed, paraffin-embedded tissue blocks of 62 hysterectomy specimens that were diagnosed as endometrioid carcinoma in the teaching labora
... Show Moreولد ابو بكر محمد بن زكريا الرازي في الري سنة 250هـ (864م) وتعمق في الطب والكيمياء والفلك والأدب والفلسفة وهو أحد مشاهير الاطباء في زمانه وهذا هو السبب الذي دعاه لأن يتنقل من بلاط الى اَخر , ولم ينعم بالأستقرار في حياته بالنظر الى تقلب الأهواء والاُمراء وأضطراب الأحوال السياسية . قام برحلات كثيرة , وعهدت اليه ادارة بيمارستان ( مصح ومشفى ) الري ثم قام بهذه المهمة نفسها في بغداد.
لقب بـ( طبي
... Show MoreBackground: There are various secreted proteins affecting the prognosis of oral squamous cell carcinoma (OSCC) and one of them is Angiopoietin-2(Ang-2) which is thought to have an essential role in the development and progression of the tumor. Aim of the study: This study was conducted to determine the expression of (Ang-2) in (OSCC) to assess its correlations with clinicopathological parameters of the tumor. Material and Methods: 36 formalin- fixed, paraffin- embedded tissue blocks histologically diagnosed as OSCC were examined for Ang-2 immunohistochemical expression semi quantitively. Results: The expression of Ang-2 was significantly associated with histopathological grade (P value=0.023), while there is no significant association wi
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