Background: The median nerve in paraplegic patients, who must rely on increased hand activities including transfer and wheel-chair propulsion, may be subjected to increased pressure, so that the incidence of carpal tunnel syndrome (CTS) may be higher than that in the normal population.
Objectives: To study the prevalence and the severity of carpal tunnel syndrome in Iraqi paraplegic patients and to identify the effect of duration of the injury as a possible factor related to its occurrence to avoid any chronic problems which interfere with the hand functions since these patients are greatly dependent on their hands for their daily activities.
Patients and Methods: Fifty paraplegic patients (100 hands), whose level of spinal cord injury was below D2, and fifty normal control subjects were included in this study. All patients studied in this work had complete spinal cord injury and were stabled medically and neurologically.
Clinical examination for the signs and symptoms of CTS as well as nerve conduction studies were carried out in both median and ulnar nerves for their sensory and motor components eliciting values for distal latencies for all patients and the control groups.
Results: Thirty percent of the paraplegic patients (15 patients) had signs and symptoms consistent with carpal tunnel syndrome (CTS), and all of them had electrodiagnostic confirmation of this injury.
Seventy percent of these paraplegic patients (35 patients) had no signs and symptoms suggestive of CTS, and only nearly about forty eight percent (17 patients) of them had only electrodiagnostic confirmation of CTS. Overall, 64% of the 50 paraplegic patients had CTS (32 patients). Nine paraplegic patients (18%) exhibiting bilateral CTS. Eight paraplegic patients (16%) had abnormal electrophysiological findings involving the ulnar nerve at the wrist and all of them had electrophysiological findings of CTS.
There was a sharp increase in incidence of occurrence of CTS from 6.3% in the group 1 to 5 years from injury to 13.7% in the group 6 to 10 years, and to 25% in the group 11 to 15 years, and again a very big increase to 50% in the group 16 years and over from injury.
Conclusion: Early testing of the median and ulnar nerve function, even in asymptomatic patients within the first 5 years of the injury, is recommended so for early detection, preventive and/or curative measures to be undertaken considering the fact that these patients are greatly dependent on their hands for their daily activities.
The current study was designed to compare some of the vital markers in the sera of diabetic and neuropathy patients via estimating Adipsin, Fasting blood Glucose(FBG), Glycated(HbA1c) hemoglobin, Homeostasis Model Assessment Index (Homa IR ), Cholesterol, High density lipoprotein (HDL), Triglycerides (T.G), Low-density, and lipoprotein (LDL), Very Low Density Lipoprotein (VLDL), in sera of Iraqi patients with diabetes and neuropathy. A total of ninety subjects were divided into three groups: group I (30 diabetic with neuropathy males) and group II (30 diabetic males without neuropathy), and 30 healthy sujects were employed as control group. The results showed a significant decline in Adipsin levels (p>0.05) in neuropathy, T2DM g
... Show MoreVitamin K-dependent protein (VKDP) contributes to the development of lung cancer. The purpose of this research was to better understanding of the role of blood matrix Gla protein (MGP), VKDPs, Malondialdehyde (MDA), Superoxide dismutase (SOD) and Vitamin K (Vit K) in Iraqi patients with lung cancer before and after the first cycle of chemotherapy. Blood samples were collected from Al amal National Hospital for cancer treatment from October 2021 to May 2022, and a total of 80 samples were collected, divided into two groups (40 patient before taking a chemotherapy and 40 patients after taking chemotherapy), ranging in age from 20 to 45 years old. The results showed that although there were highly statistically significant differences in MD
... Show MoreBackground: Breast cancer is a complex, multifaceted disease encompassing a great variety of entities that show considerable variation in clinical, morphological and molecular attributes.
Objective: The aim of this study to evaluate patients’ molecular profile (Estrogen receptor, Progesterone receptor, HER2/neu and Ki-67).
Patients & Methods: This is a cross-sectional descriptive study was done in Baghdad oncology teaching hospital from December 2015 to April 2016, carried on 100 breast cancer female patients with their age range from 27 to 73 years old and with their histopathology reports and (IHC) results.
Results: The highest incidence of breast cancer among patients in 5th (40-49 years) and 6th (50-59 years) decades o
Background: Rheumatoid arthritis (RA) is an autoimmune disease that results in a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks flexible (synovial) joints. Many cases are believed to result from an interaction between genetic factors and environmental exposures. Epstein-Barr virus (EBV) is associated with several autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis and multip
... Show MoreBackground: Acute coronary syndrome refers to any group of clinical symptoms compatible with acute myocardial ischemia including unstable angina (UA), Non-ST-segment elevation myocardial infarction (NSTEMI) & ST-segment elevation myocardial infarction (STEMI).
Apelin is a novel endogenous peptide with inotropic and vasodilatory properties, it was recently reported that serum measurements of apelin were similar to its immunohistochemical data in vessels and heart tissues.
Objectives: This study aims to evaluate serum levels of apelin in patients with Acute Coronary Syndrome related to severity of presentation.
Patients and Methods: The present study was conducted during the period from September 2014 until March 2015. Fifty-n
Background: Multiple sclerosis (MS) is one of the increasing prevalent neurologic disorders. Epidemiologic and family studies implicate genetic and environmental factors in determining
susceptibility to MS. The exact effect of the former is intended for investigation in our study.
Objectives: The objective of the study is to compare the demographic features, clinical presenting features, and clinical course between familial and sporadic cases of MS.
Materials and Methods: this is a retrospective cohort study conducted in Multiple Sclerosis Center in the Medical City in Baghdad. The records of the MS center in Baghdad Teaching Hospital were surveyed, and data from 13 patients with positive family history of MS
Background: Multiple sclerosis (MS) is one of the increasing prevalent neurologic disorders. Epidemiologic and family studies implicate genetic and environmental factors in determining
susceptibility to MS. The exact effect of the former is intended for investigation in our study.
Objectives: The objective of the study is to compare the demographic features, clinical presenting features, and clinical course between familial and sporadic cases of MS.
Materials and Methods: this is a retrospective cohort study conducted in Multiple Sclerosis Center in the Medical City in Baghdad. The records of the MS center in Baghdad Teaching Hospital were surveyed, and data from 13 patients with positive family history of MS
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Background: rheumatoid arthritis (RA) is a systematic autoinmume disease with prevalence of 1% world wild, it is characterized by chronic inflammation of synovial joints, which commonly leads to progressive joints destruction and consequent disability with reduction in quality of life of life.
Background: Cognitive dysfunctions in epileptic patients may develop due to the neurophysiologic changes related to seizures or antiepileptic drugs.
Objectives: The aim of this longitudinal study was to evaluate the cognitive dysfunction in epileptic patients under antiepileptic drug therapy by the aid of event related potentials.
Patients & Method: P300 latencies were obtained from Fz, Cz and Pz electrodes positions from both epileptic patients (n = 224) and age and sex matched control group (n = 91). Epileptic patients were classified either having partial epilepsy, generalized epilepsy or both partial and generalized epilepsy (combined epilepsy). EEG and p300 test repeated for each patient every three months for one year. Th