Backgrounds: Despite advances in management of diabetes mellitus, it remains one of the major causes of morbidity and mortality, yet diabetic nephropathy is one of the main complications of diabetes mellitus. .Microalbuminuria is the beginning to the renal complications of diabetes mellitus; it is a significant index of early detection as well as monitoring the progression of diabetic nephropathy.                                                       

The (CTLA-4) encodes of the T cell receptor involved in the control of T cell
proliferation and mediates T cell apoptosis. The contribution of CTLA-4 gene
variants to type 1 diabetes has been analyzed in several ethnic groups. In this study,
the association of CTLA-4 +49 A/G polymorphism with type 1 diabetes was
investigated in Egyptian patients. Sixty type 1 diabetic patients (25 males and 35
females) and 60 healthy individuals (33 males and 27 females) subjects formed the
studied populations. CTLA-4 A/G polymorphism at position 49 in exon 1 was
identified using allele specific methods. Patient numbers with A/G, A/A and G/G
genotypes were 45 (75.0 %), 6 (10.0 %) and 9 (15.0%) while in healthy controls,
these w

Background: Diabetic patients with accompanied dyslipidemia are soft targets for cardiovascular diseases. An early intervention to normalize circulating lipids has been shown to reduce
cardiovascular complications and mortality. Glycated hemoglobin (HbA1c) is a routinely used marker for long-term glycemic control.
Objective: to investigate the role of HbA1c as a marker of circulating lipids in type 2 diabetic patients
Subjects and Methods: A total of 450 type 2 diabetic patients (214 males and 236 females), mean age was 55.5 ± 9.35. who attended the National Diabetic Center, Al-Mustansiria university during the period from December 2010 to May 2011 were included in this study Fasting venous blood sample

Background: Diabetic nephropathy is a common complication of diabetes mellitus type2. The neutrophil gelatinase Associated lippocallin (NGAL) is an ubiquitous protein consist of 178 amino acid. NGAL can be identified in plasma and urine starting 2- 4 hours after a kidney injury resulting changes in glomerular filtration and tubular reabsorption and with increased secretion in tubular epithelial cells.
Objective: This study aimed to evaluate the role of serum Neutrophil Gelatinse Associated Lipocallin (NGAL) in early detection nephropathy.
Method : This study was conducted in Medical City, Baghdad Teaching Hospital during the period from December 2015to June 2016.The study included (90) subjects with age range between (30 – 56)yea

Background: Diabetes is a serious risk factor for atherosclerotic cardiovascular disease and an important cause of mortality. Dyslipidemia is commonly related to type 2 diabetes, and the atherogenic index of plasma is a strong marker to predict the risk of atherosclerosis and coronary heart disease.

Objective: To study the association of atherogenic indices lipids in type 2 diabetic Iraqi patients with cardiovascular disease.

Patients and Methods: This clinical study was conducted at Baghdad Teaching Hospital/ Medical City-Baghdad from October 2022 to February 2023. Sixty type 2 diabetic patients were recruited for this study: 30 patients with cardiovascular disease and 30

Back ground:  Peripheral   neuropathy is a common complication of diabetes mellitus. However, patients with diabetes are more vulnerable to develop chronic inflammatory demyelinating  peripheral  polyradiculoneuropathy (CIDP) which is an  acquired immune mediated disorder.

Subjects and methods: Three groups of subjects of either sex involved in this study; fourty one (41) patients with diabetic CIDP, fourty six (46)patients  with diabetic peripheral  polyneuropathy and fourty one (41) control subjects. Sensory and motor nerve conduction study (NCS) and electromyography (EMG) of both upper and lower limbs were performed for each subjects. This study was cond

Background: Type 2 diabetes mellitus (T2DM) is a chronic disorder that constitutes a major health problem worldwide. Toxoplasma gondii is an intracellular parasite that may infect any nucleated cell. Toxoplasmosis is becoming a worldwide health threat, infecting 30–50% of the world’s human population. The studies that have been undertaken to investigate the link between T. gondii infection and diabetes have shown contradictory fi ndings. This research aimed to look at the possible link between T2DM and T. gondii infection. Methods and Subjects: The enzyme-linked immunosorbent assay (ELISA) approach was used to screen for T. gondii IgM and IgG antibodies in 69 patients with T2DM and 92 seemingly healthy persons as controls. Resul

Background: Frozen shoulder affects 2-5% of the
general population, and around 10-30% of diabetic
patients. It affect mainly the non-dominant shoulder,
and has more incidence in patients with poor
glycemic control.
Objective: To detect the incidence of frozen
shoulder in type 2 diabetic patients attending the
Specialized Center for Endocrinology and Diabetes
in Baghdad.Patients and methods: One hundred
patients with frozen shoulder were included in the
study from a total number of 580 type 2 diabetics
over a period of six months. 70 patients were
females and 30 patient were males. All were
investigated for fasting blood
glucose and HbA1c.
Results: The non-dominant shoulder was
involved in

Type 2 diabetes mellitus (T2DM) became the most prevalent health problem. Almost half of the world's people are ignorant that have diabetes. Menopause occurs as an important alteration in women through which take place the change in sex hormones, distribution in fat،s body, and metabolism, altogether which participate in the metabolism disease such as type 2 diabetes mellitus. Several studies have appeared the association between the TCF7L2 gene and different diseases like type 2 diabetes mellitus (T2DM). This study aimed to detect the relation of the genetic variation polymorphism for the TCF7L2 gene (rs12255372 G/T) in Iraqi women menopausal with T2DM. The outcomes indicated the increased levels of biochemical characteristics including H

Background: Cigarette smoking is the leading avoidable cause of morbidity and mortality in the general population; however its effects on people with diabetes are even more profound. The adipocytokines  leptin and  adiponectin  play an important role in regulating glycemia, lipidemia, endothelial dysfunction, and proinflammatory mechanisms .

Objective: We aimed to investigate the profile of  adiponectin and leptin in type 2 diabetic smokers and non- smokers.

Patient and Methods: Ninety overweight males attending the Teaching Laboratories, Medical City were enrolled in this study, they were arranged as 30 diabetics non smoker, 30 diabetics smokers and 3