Background: Peripheral blood lymphocytes (PBL)of Rheumatoid arthritis (RA)patients have a property of phenotypic and functional activation. Glutathione S- transferase pi (GSTπ) has been implicated in playing an important role in the initiation and progression of cellular activation.
Objectives: To determine the percentage of cellular expression of GSTπ in the lymphocytes of RA patients in comparison with controls and to explore the relation between its cellular expression and disease activity pattern.
Patients and Methods: This prospective study included46 RA patients and 17 healthy controls. Blood samples were taken and from all subjects PBL were isolated and then smeared on slides. The cellular reactivity for GSTπ was determined by immunocytochemistry technique.
Results: This study found lower expression of GSTπ in the RA patients with a statistical significant difference with control group, while no statistical difference was found in RA with high and minimum disease activity groups. No correlation was observed between GSTπ with Disease Activity Score (DAS).
Conclusion: Although the decrease in the expression of GSTπ in PBLs was pronounced in RA patients, however it doesn’t correlate with disease activity state.
This research represents outcrops of rocks at Cliffs of Tigris river ( Terraces ), most are Conglomerate, Sandstone, Siltstone and Clay stone. The research covers several aspects ; it includes a collection of field information from unstable rock slopes at (6) stations representing all the rock failure types that happened or likely to happen . In each station rock slopes are completely surveyed ; also the rocks are described in an engineering way and a complete discontinuity survey is carried out according to Anon (1972,1977) and their relationship with the rock failure is established. The field study shows that rock failures include toppling (mostly insecondary type ), rock fall. Point load test shows t
... Show MoreZG Abdulrazaq, MR Younus, Nasaq, 2023
Perceptions of deity have practical effects in a person’s life, especially in his attitudes toward natural things since nature was created, in which man has treated it as something sacred. The Greek philosophers before Plato and Aristotle did not find in them the idea of divinity clear. Rather, they all searched for the first substance or the first cause of existence, and then gave it all the attributes of God from eternity and eternity, and considered it a first reason without which the universe would not have existed. knowledg
SKF Dr. Abbas S. Alwan, Dhurgham I. Khudher, INTERNATIONAL JOURNAL OF ENGINEERING SCIENCES & RESEARCH TECHNOLOGY, 2015
Pseudomonas aeruginosa and Klebsiella pneumoniae appears good growth when replicate to culture with heavy crude oil. K. pneumoniae was less ability to biodegrade the heavy crude oil (66.22 wt.%) compare with P. aeruginosa 74 wt.%). Also the emulsion percent were about 64.8 % and 62.5 % for K. pneumoniae and P. aeruginosa, respectively. The results showed that the emulsions produced from both the strains decrease the surface tension of the media from 68.43 Mn/m (for control sample) to 44.50 and 43.30 Mn/m for P. aeruginosa and K. pneumoniae, respectively. The optimum temperature and pH for the hydrocarbons biodegradation were 28 ºC and 7, respectively. The incubation period of 28 days of the isolated increased hydrocarbons biodegradation
... Show MoreIn this work, new kinds of blocking sets in a projective plane over Galois field PG(2,q) can be obtained. These kinds are called the complete blocking set and maximum blocking set. Some results can be obtained about them.
ABSTRACT Background: Neuropilin 1(NRP1) is considered a novel non - tyrosine kinase co- receptor for the vascular endothelial growth factors (VEGF). First discovered on migrating neurons. NRP1is suggested to be up-regulated in cells of different types of cancer and implicated with advanced disease. The aim of this study was to investigate the variation in expression of NRP1 in oral, laryngeal and skin squamous cell carcinoma. Materials and methods: Tissue sections from 120 formalin fixed- paraffin embedded blocks histopathologically diagnosed as oral, laryngeal and skin SCC (40 blocks for each),immunohistohemically stained in immunoperoxidase method with monoclonal antibodies to NRP1, the localization of expression was examined and the res
... Show MoreEnergy Loss Function (ELF) of 2 5 Ta O derived from optical limit
and extended to the total part of momentum and their energy
excitation region ELF plays an important function in calculating
energy loss of electron in materials. The parameter Inelastic Mean
Free Path (IMFP) is most important in quantitative surface sensitive
electron spectroscopies, defined as the average distance that an
electron with a given energy travels between successive inelastic
collisions. The stopping cross section and single differential crosssection
SDCS are also calculated and gives good agreement with
previous work.
The purpose of this research was to examine the impact of varying doses of ginger powder on broiler productivity. There were 180 commercial strain Ross 308 day old chicks utilized in the experiment, and each chick was weighed and allocated randomly among four treatments. Three different treatments were tested, each with a replication of 15 chicks. The diet was supplemented with 0.5, 1.0 and 2.0g/kg of ginger powder, respectively, as a control. As compared to the other treatments, the control group had considerably higher body weights, weight growth, feed intake, and feed conversion ratio. Ginger powder use was shown to have a detrimental impact on growth in this investigation.
The effect of crude colicin extracted from E. coli isolated from
urinary tract infection patients on phagocytosis in vitro was studied . Results showed that the effect of crude colicin on phagocytic cells and their activities were concentration dependent. Low concentration (50
Mg/ml) have no significant effect (p>O.OS) on shape, size, migration and engulfment activity of phagocytic cells, while (50, 100 Mg/ml)
enhanced killing activity and increase superoxide ( 02 ) production as indicated by (NBT) test. But high concentration (500 mg/ml) of crude colicin caused inhibition of phagocytic cel
... Show More