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A Comparative Study of Serum Amyloid A2 with Anti-cyclic Citrullinated Peptide antibody in the prognosis of a Group of Rheumatoid Arthritis Patients in Iraq

Background: Rheumatoid arthritis (RA) is an inflammatory disease of unknown etiology characterized by joint inflammation and the presence of autoantibodies, mostly Anti-cyclic citrullinated peptide antibody (ACCP) which are released when the body loses its ability to distinguish between self and foreign molecules. Serum amyloid A2 (SAA2) is an acute phase protein produced in response to inflammatory conditions including RA.

Objectives: To investigate the prognostic ability of SAA2 in comparison with ACCP and the prediction of disease activity and response to treatment by Methotrexate and Etanercept in Iraqi RA patients.  

Patients and methods: A case control study, on a total of 150 individuals; 100 patients and 50 healthy controls. The study was carried out between November 2021 to February 2022 in Baghdad Teaching Hospital. The patients were recruited according to the American College of Rheumatology 2010 criteria. The biomarkers’ levels were measured by enzyme-linked immunosorbent assay.

Results: The levels of ACCP and SAA2 in RA patients were significantly higher compared to healthy controls (p<0.001), and were higher among patients with active disease than those with inactive disease, with the levels being higher in both categories than the healthy controls (p<0.00). Highly significant ACCP levels were found in patients without treatment than those who have received treatment (methotrexate or etanercept) (p<0.00). SAA2 level in patients without treatment were not significantly different from those of patients who have received methotrexate (p>0.05) but significantly from those who have received etanercept (p≤0.02). A significant positive correlation was found between ACCP and SAA2 (r=0.553, p<0.001), with the sensitivity being (72%, 97%) and the specificity being (98%, 84%) respectively.

Conclusion: ACCP and SAA2 have promising prognostic ability and disease activity prediction of RA with response to treatment (Methotrexate, Etanercept).

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Publication Date
Sun Mar 01 2015
Journal Name
Baghdad Science Journal
Determination of Serum CA125 and evaluate its efficiency as screening tool For Early Detection of Ovarian Tumors

Epithelial ovarian cancer is the leading cause of cancer deaths in women. To date, an effective screening tool for ovarian cancer has not been identified Several clinical and biological factors including serum cancer antigen 125 (CA- 125) have been assessed for prognostic and predictive relevance CA-125 is an epithelial marker derived from coelomic epithelium. It is elevated in 90% of advanced ovarian cancers and in 50% of early ovarian cancers while 20% of ovarian cancers have low or no expression of CA- 125 CA-125 concentrations were measured by Mini Vidas test (VIDAS CA125 II / BIOMERIEUX / France). The median CA-125 levels were significantly higher in the sera of ovarian cancer patients than in those with benign tumors an

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Publication Date
Mon Jan 28 2019
Journal Name
Journal Of The College Of Education For Women
The statistic structure of the title in the poetry of Muhammed Ali Kazim Haider

In this research, we attempt to show the extent of harmony in an aspect of the text according to the stylistics for the Knowing of the stylistic value of the title threshold, and the pathways of titles that suggest and support the meaning when the recipient reads the literary text, in addition to the interpretations that reflect the purposes of the poet who contributed to the drawing of his poetic achievement. The research presented a brief about the poet and his most important works, because they are the text which will be studied according to the stylistics. The research also explained the concept of style and the stylistics in the preface , because of the stylistic is the method adopted by the research to study the title thresholds in

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Publication Date
Tue Nov 19 2024
Journal Name
Journal Of Baghdad College Of Dentistry
The Electrophoretic Deposition of Nano Al2O3 and AgNO3 on CpTi Dental Implant (An in vitro and in vivo study)

Background: Even the wide use of dental implants, still there is a proportion of implants are failed due to infection. Much considerable attention has been paid to modify the implant surface. Coating of dental implant with a biocomposite material of suitable properties can improve osseointegration. And this is the main concern of this study. The aim of present study was to evaluate the use of a biocomposite coating of dental implant with (ceramic nano Al2O3 and metalic AgNo3) on the bond strength at bone – implant interface and tissue reaction. Materials and methods: A total number of forty-eight screws, CpTi dental implant used in this study. Half of these screws were coated with a biocomposite material of nano (Al2O3and AgNo3), thi

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Publication Date
Tue Apr 01 2008
Journal Name
Journal Of The Faculty Of Medicine Baghdad
efficacy of measles vaccine in study among primary school children during measles outbreak in Iraqi for the year 2004

Background: progress towards the control of measles require a national capacity to measure program affectiveness.

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Publication Date
Sun Jan 01 2017
Journal Name
البحوث التربوية والنفسية
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Publication Date
Thu Oct 01 2020
Journal Name
The Asian Efl Journal
The Effect of Flow as a Strategy on EFL Student-teachers' Performance and their Flow

This study aims at suggesting flow as a strategy for training female EFL student-teachers in the teaching training course and finding out the effect of this strategy on their performance and their flow state. The training course syllabuses will be constructed according to the flow nine factors and the teaching skills. The measurement tools are the student-teacher performance checklist that has already been used by the department of English language and SHORT Flow State Scale (S FSS-2). The study population is represented with the (60) female student-teachers/ fourth stage/ evening studies at theEnglish department /college of education for women/the University of Baghdad. The study is used the experimental design in that (30) of the student-

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Publication Date
Fri Sep 24 2021
Journal Name
Applied Sciences
The Impact of Calcitriol on Orthodontic Tooth Movement: A Cumulative Systematic Review and Meta-Analysis

A cumulative review with a systematic approach aimed to provide a comparison of studies’ investigating the possible impact of the active form of vitamin D3, calcitriol (CTL), on the tooth movement caused by orthodontic forces (OTM) by evaluating the quality of evidence, based on collating current data from animal model studies, in vivo cell culture studies, and human clinical trials. Methods: A strict systematic review protocol was applied following the application of the International Prospective Register of Systematic Reviews (PROSPERO). A structured search strategy, including main keywords, was defined during detailed search with the application of electronic database systems: Medline/Pubmed, EMBASE, Scopus, Web of Science, and

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Publication Date
Sun Sep 30 2018
Journal Name
Scientific Journal Of Silesian University Of Technology. Series Transport
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Publication Date
Fri Oct 24 2014
Journal Name
Journal Of Religion And Health
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Publication Date
Fri Jan 01 2021
Journal Name
Desalination And Water Treatment
Electrosorption of cadmium ions from the aqueous solution by a MnO2/carbon fiber composite electrode

The nanostructured MnO2 /carbon fiber (CF) composite electrode was prepared using the anodic electrodeposition process. The crystal structure and morphology of MnO2 particles were determined with X-ray diffraction and field-emission scanning electron microscopy. The electrosorptive properties of the prepared electrode were investigated in the removal of cadmium ions from aqueous solution, and the effect of pH, cell voltage, and ionic strength was optimized and modeled using the response surface methodology combined with Box–Behnken design. The results confirm that the optimum conditions to remove Cd(II) ions were: pH of 6.03, a voltage of 2.77 V, and NaCl concentration of 3 g/L. The experimental results showed a good fit for the Freundli

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