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iqjmc-1888
Detection of BRAFV600E Biomarker In Patients With Colorectal Cancer Using Immunohistochemical Techniques / Clinico-Pathological Study
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Background :

Colorectal cancer (CRC) is the 4th common gastrointestinal cancer. (BRAFV600E) is a member of RAF family of serine/threonine protein kinases that function to regulate the (MAPK) / (ERK) pathway. BRAFV600E mutated CRC are associated with right-sided primary tumors, older women and high-grade tumors.

Aims of the study:

Study the immunohistochemical expression of BRAFV600E biomarker in a sample of Iraqi patients with colorectal cancer and the correlation of BRAFV600E expression with other clinicopathological variables such as patient's age and tumor grade.

 

Materials and Methods :

in this prospective study a total of 90 colorectal cases of a sample of Iraqi patients were collected from teaching labs of AL-Yarmouk Teaching Hospital including 60 cases of colorectal carcinoma and 30 cases of colorectal adenoma.

 

Result: BRAFV600E biomarker was positive in 16.6% of colorectal carcinoma group and negative in colorectal adenoma group.

 

Conclusions:

BRAF expression was higher in older patients ages & higher tumor stages and there is no expression of BRAFV600E in adenoma cases.

 

 

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Publication Date
Thu Jan 12 2023
Journal Name
Mathematics
Dynamical Behavior of a Cancer Growth Model with Chemotherapy and Boosting of the Immune System
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In this study, we set up and analyze a cancer growth model that integrates a chemotherapy drug with the impact of vitamins in boosting and strengthening the immune system. The aim of this study is to determine the minimal amount of treatment required to eliminate cancer, which will help to reduce harm to patients. It is assumed that vitamins come from organic foods and beverages. The chemotherapy drug is added to delay and eliminate tumor cell growth and division. To that end, we suggest the tumor-immune model, composed of the interaction of tumor and immune cells, which is composed of two ordinary differential equations. The model’s fundamental mathematical properties, such as positivity, boundedness, and equilibrium existence, are exami

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Publication Date
Wed Oct 01 2014
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Experience with feeding jejunostomy.
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Background: Enteral nutrition is a widely used, standard-of-care technique for nutrition support in critically ill and trauma patients.

Objective: to determine the role of feeding jejunostomy as a safe way for enteral nutrition in patients who meet the criteria for its use.

Method: prospective, comparative study done in the 3rd. surgical unit at Baghdad Teaching Hospital from 1st.of January 2003 till 1st. of April 2009, of 230 patients who fit the criteria for feeding jejunostomy insertion. The patients were divided into 2 groups (those with feeding jejunostomy 122 patients (53%) and without feeding jejunostomy 108 patients (47%)). We follow up these patients using the pa

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Publication Date
Fri Nov 24 2023
Journal Name
Iraqi Journal Of Science
Study of Epidemiology of Toxoplasmosis in Hemodialysis Patients in Baghdad Hospitals
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This study aims to assess some seroprevalence of toxoplasmosis in chronic renal failure (CRF) patients undergoing hemodialysis in dialysis centers in some Baghdad hospitals, by testing the blood samples with enzyme linked Immunosorbant assay (ELISA) IgG and IgM, to determine the incidence of toxoplasmosis in hemodialysis patients. Hemodialysis patients infected with Toxoplasma. gondii were appeared with 129(32.25%) seropositive anti-Toxoplasma IgG. The age groups (43-51) year and (52-60) years of hemodialysis patients showed the highest percentage of anti-Toxoplasma gondii antibodies. An increase of the seropositivity rate was detected with increasing length of time on hemodialysis treatment. Females had the highest significant percentag

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Publication Date
Mon Aug 26 2019
Journal Name
Iraqi Journal Of Science
Seroprevalence of Toxoplasmosis in patients with chronic liver disease in Baghdad
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The influence of Toxoplasma gondii in the pathogenesis of hepatic disease has lately  had considerable attention. The objective of this study is to assess the seroprevalence of T. gondii infection in patients with chronic liver disease from Baghdad-Iraq. All patients have attended Gastroenterology and Hepatology  Teaching Hospital, Medical city in Baghdad, Iraq An analytical case–control study was achieved from September to November 2018. Seventy male patients with chronic liver disease (CLD) and 70 control males  (free of chronic liver diseases) participated in this study, their ages were between (18-80) years old. Serum samples were taken from all subjects and were analysed with enzyme-linked imm

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Publication Date
Sat Jan 30 2021
Journal Name
Iraqi Journal Of Science
Detection of Road Traffic Congestion Using V2V Communication Based on IoT
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Intelligent Transportation Systems (ITS) have been developed to improve the efficiency and safety of road transport by using new technologies for communication. Vehicle to Vehicle (V2V) and Vehicle to Infrastructure (V2I) are a subset of ITS widely used to solve different issues associated with transportation in cities. Road traffic congestion is still the most significant problem that causes important economic and productivity damages, as well as increasing environmental effects. This paper introduces an early traffic congestion alert system in a vehicular network, using the internet of things (IoT) and fuzzy logic, for optimizing the traffic and increasing the flow. The proposed system detects critical driving conditions, or any emerge

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Publication Date
Tue Dec 01 2020
Journal Name
Baghdad Science Journal
Detection of Suicidal Ideation on Twitter using Machine Learning & Ensemble Approaches
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Suicidal ideation is one of the most severe mental health issues faced by people all over the world. There are various risk factors involved that can lead to suicide. The most common & critical risk factors among them are depression, anxiety, social isolation and hopelessness. Early detection of these risk factors can help in preventing or reducing the number of suicides. Online social networking platforms like Twitter, Redditt and Facebook are becoming a new way for the people to express themselves freely without worrying about social stigma. This paper presents a methodology and experimentation using social media as a tool to analyse the suicidal ideation in a better way, thus helping in preventing the chances of being the victim o

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Publication Date
Sat Dec 03 2011
Journal Name
Ibn Al-haitham Journal For Pure And Applied Science
Detection of shoreline change in AL-Thirthar Lake using remotely sensed imagery and topography map
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Publication Date
Wed Oct 17 2018
Journal Name
Journal Of Economics And Administrative Sciences
comparison between the methods estimate nonparametric and semiparametric transfer function model in time series the Using simulation
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 The transfer function model the basic concepts in the time series. This model is used in the case of multivariate time series. As for the design of this model, it depends on the available data in the time series and other information in the series so when the representation of the transfer function model depends on the representation of the data In this research, the transfer function has been estimated using the style nonparametric represented in two method  local linear regression and cubic smoothing spline method The method of semi-parametric represented use semiparametric single index model, With four proposals, , That the goal of this research is comparing the capabilities of the above mentioned m

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Publication Date
Mon Sep 23 2019
Journal Name
Baghdad Science Journal
Hazard Rate Estimation Using Varying Kernel Function for Censored Data Type I
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     In this research, several estimators concerning the estimation are introduced. These estimators are closely related to the hazard function by using one of the nonparametric methods namely the kernel function for censored data type with varying bandwidth and kernel boundary. Two types of bandwidth are used:  local bandwidth and global bandwidth. Moreover, four types of boundary kernel are used namely: Rectangle, Epanechnikov, Biquadratic and Triquadratic and the proposed function was employed with all kernel functions. Two different simulation techniques are also used for two experiments to compare these estimators. In most of the cases, the results have proved that the local bandwidth is the best for all the

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Publication Date
Sun May 02 2021
Journal Name
Journal Of Accounting And Financial Studies ( Jafs )
Rationalization of costs by using the tool of the quality function deployment: / applied research in the State Company for Textile and Leather Industries
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The research aims to apply one of the techniques of management accounting, which is the technique of the quality function deployment on the men's leather shoe product Model (79043) in the General Company for Textile and Leather Industries by determining the basic requirements of the customer and then designing the characteristics and specifications of the product according to the preferences of the customer in order to respond to the customer's voice in agreement With the characteristics and technical characteristics of the product, taking into account the products of the competing companies to achieve the maximum customer satisfaction, the highest quality and the lowest costs. Hence, the importance of research has emerged, which indicat

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