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sibs of Iraqi families affected by congenital adrenal hyperplasia

Background:

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Publication Date
Sun Jul 03 2011
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Congenital adrenal hyperplasia: hospital based study

Background: Congenital adrenal hyperplasia is a family of autosomal recessive disorders of cortisol biosynthesis. Depending on the enzymatic step that is deficient, there may be signs, symptoms, and laboratory findings of mineralocorticoid deficiency or excess; incomplete virilization or premature puberty in affected males; and virilization or sexual infantilism in affected females. The most frequent is 21-hydroxylase enzyme deficiency, accounting for more than 90% of cases.
Objectives: to review cases of congenital adrenal hyperplasia registered in children welfare teaching hospital- medical city- Baghdad.
Patients and method: This study included all patients who were presented and registered in the e

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Publication Date
Thu Sep 29 2016
Journal Name
Enzyme Research
Molecular Analysis of CYP21A2 Gene Mutations among Iraqi Patients with Congenital Adrenal Hyperplasia

Congenital adrenal hyperplasia is a group of autosomal recessive disorders. The most frequent one is 21-hydroxylase deficiency. Analyzing CYP21A2 gene mutations was so far not reported in Iraq. This work aims to analyze the spectrum and frequency of CYP21A2 mutations among Iraqi CAH patients. Sixty-two children were recruited from the Pediatric Endocrine Consultation Clinic, Children Welfare Teaching Hospital, Baghdad, Iraq, from September 2014 till June 2015. Their ages ranged between one day and 15 years. They presented with salt wasting, simple virilization, or pseudoprecocious puberty. Cytogenetic study was performed for cases with ambiguous genitalia. Molecular analysis of

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Publication Date
Mon Jul 19 2021
Journal Name
Challenges In Disease And Health Research Vol. 10
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Publication Date
Tue Jul 01 2008
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Congenital coronary anomalies in Iraqi adult population

Background: Geographic variations in the incidence of different congenital coronary anomalies are well known, but infrequently studied in the Iraqi population.
Recognition of coronary anomalies is important in patients undergoing coronary arteriogrphy; coronary interventions and cardiac surgery .Variation in the frequency of primary congenital coronary anomalies may possibly have a genetic background. 
Patients and methods: Three thousands adult patients underwent diagnostic coronary angiography at two cardiac centers in Baghdad between January 2003 to March 2006. Their angiographic films were reviewed by at least two experts in coronary angiographic study.
Results: Among 3000 adult patients wh

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Publication Date
Mon Jul 01 2013
Journal Name
Journal Of The Faculty Of Medicine Baghdad
Congenital Anomalies among Newborns Admitted in Tertiary Hospital; Iraqi Experience

Background: Congenital anomaly is any alteration present at birth of normal anatomic structure and has cosmetic, medical or surgical significance
Objective: To determine the pattern of congenital anomalies in neonates admitted to tertiary neonatal care unit and to determine the impact of some factors related to congenital anomalies with and without congenital anomalies.
Patients and methods: A case control study was carried out during 6 months period (1St of January to 30th of June 2011). Neonates with and without congenital anomalies admitted to Children Welfare Teaching Hospital were included in the study as a case and control group. Demographic characteristics of both parents and neonates, Consangui

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Publication Date
Wed Feb 08 2023
Journal Name
Iraqi Journal Of Science
Morphological Description and Histological Structure of Adrenal Gland in Black Iraqi Partridge Francolinus francolinus

The objective of this study was to investigate the morphological description and histological structure of adrenal gland in Iraqi black partridge Francolinus francolinus from Iraqi environment. Twenty adult healthy birds (male and female) were used in present study. They were measured and adrenal glands were removed, measured and fixed by 10% formalin and formalin and chromate fixative then stained with rotein histochemical stain (Harris hematoxylin and eosin stain (H&E), periodic acid Schiff (PAS), Azan and Mallory stain). The partridge had a small couple of adrenal glands of yellow colour they are located in abdominal cavity nearby the margin of superior kidney lobe. These are small, ovoid glands lying just cranial to the kidneys a

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Publication Date
Sat Dec 31 2022
Journal Name
Al-kindy College Medical Journal
Prevalence of Congenital Toxoplasmosis and Congenital Rubella among Suspected Infants in Baghdad

Congenital toxoplasmosis (CT) and congenital rubella (CR) infections are well-known causes potentially leading to devastating consequences. This report aims to address the prevalence of each of these infections among suspected infants in a pediatric hospital in Baghdad.

The study sample includes 120 blood samples of suspected infants consulting Al-Alwyia pediatric teaching hospital over one year. This report represents an extension of a previous article published in Al-Kindy College Medical Journal KCMJ about cytomegalovirus infection (CMV). Using the enzyme-linked immunosorbent assay (ELISA) method, the results show that 5.8% and 5% were positive for specific IgM antibodies for rubella and toxoplasmosis respectively. Results also

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Publication Date
Thu Jun 15 2023
Journal Name
Journal Of Legal Sciences
Estimating Compensation Due to those Affected by Terrorist Acts

      The research aims to study the estimation of compensation due to those affected by terrorist acts, guided by the legal systems in the Kingdom of Saudi Arabia and the experience of the French and Egyptian legislators, beginning with the dispute over the definition of terrorist act, and analyzing the extent of countries’ commitment to compensating those injured by terrorist acts, the legal basis for compensation for damage, and how the injured person is entitled to compensation and its relationship to standards Compensation and how to estimate it.

              The research reached several results, including the multiplicity of legal t

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Publication Date
Sun Dec 01 2013
Journal Name
Baghdad Science Journal
Estimation of Testosterone, Estradiol and some Markers in Sera of Iraqi Patients with Benign Prostatic Hyperplasia.

Benign prostatic hyperplasia (BPH) is one of the most common disease and major cause of morbidity in elderly men which may lead to bladder outflow obstruction and lower urinary tract symptoms (LUTS). Although sex steroid hormones play fundamental roles in prostate growth, their clinical significance is not completely clear. In the present study we assessed whether serum hormones levels as markers of prostate disease. This study includes (40) patients with benign prostatic hypertrophy and (40) control group with age rang (41-79) and (42-71) years respectively. The following biochemical investigations have been studied: Testosterone, Estradiol (E2), and Prostatic Specific Antigen (PSA) levels using ELISA method which correlated with t

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Publication Date
Sun Oct 29 2023
Journal Name
Iraqi National Journal Of Nursing Specialties
Effect of Iodine Overdose on Thyroid Hyperplasia

Objectives: study the relation between the effect of time (long time duration) with high concentration of iodine
and study its effect on the activity of the thyroid gland (homonal and histological changes).
Methodology: An experimental study was done on (30) albino rats (8 weeks of age) to know the effect of high
concentration of iodine on the activity of the thyroid gland aiormonal and histological changes) related with
time. The study last for six months for the period of I/2/2007 to 31/7/2007, the experiment was carried out in the
research lab. of pathology deparment, College of Medicine, University of Baghdad.
Results: The study shows changes in homonal levels of thyroid hormones (T3 & T4) and also histological<

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