Background:
Acute leukemias are clonal neoplastic proliferations of immature cells of the hemopoietic system. They are divided into acute myeloid leukemia (AML), acute
lymphoblastic leukemia (ALL) and acute undifferentiated leukemia (AUL). LDH has been suggested as a possible non-specific tumor marker for many years, and total serum LDH is
frequently elevated in neoplastic diseases. The aims of the study are to evaluate the significance of increased serum LDH levels in patients with acute leukemia and to
determine the importance of serum LDH level in the follow up and assessment of treatment responses.
Patients, Materials and Methods:
This study was conducted at Baghdad Teaching Hospital in Medical City during the period of October 2003 till October 2004. It included 108 patients with acute leukemias.
The patient groups were compared with 21 apparently healthy control subjects. All patients had full medical history, complete physical examination, and routine investigations and
other specific investigations e.g. BM aspiration and biopsy. Serum lactate dehydrogenase LDH level was estimated in all patients serially during diagnosis and after chemotherapy as
well as in control subjects.
Results:
Total serum LDH levels were significantly higher among patients with acute leukemias compared to that of the controls. Comparing the three types of leukemic patients, no
significant difference was observed in total serum LDH levels between AML, ALL and AUL patients. Regarding treatment, levels of total serum LDH were significantly decreased
in both remitter and non-remitter patients with acute leukemia with no significant difference between them.
Conclusion:
Although total serum LDH is higher in all acute leukemic patients, it is hardly discriminator between subsets of acute leukemia and is of little value in the prognosis and
prediction of treatment response and outcome.
The aim of this research was to study the concentrations of Uranium in the phosphorus fertilizers using Nuclear track detector (CR-39). Our present investigation is based on the study of 10 types samples for different kinds of phosphorus fertilizers which were available in the local market Some of them were Iraqi made and the others from different countries like, (Iran, Italy, Holland, Lebanon and Jordan) .. The result obtained shows that the Uranium concentration in phosphorus fertilizers samples varies from (3.59ppm) to(2.59ppm). Based on the radioactive concentration of Uranium in the samples all the results obtained between(3.59ppm) in the Iraqi super phosphate to (2.59ppm) in the mixture Iraqi phosphate fertilizer are withi
... Show MoreA simple , sensitive and accurate spectrophotometric method for the trace determination of bismuth (III) has been developed .This method is based on the reaction of bismuth (III) with arsenazo(III) in acid solution (pH=1.9) to form a blue water soluble complex which exhibits maximum absorption at 612nm .Beer's law is obeyed over the concentration range of 2-85 ?g bismuth (III) in a final volume of 20 mL( i.e. 0.1 – 4.25?g.mL-1) with a correlation coefficient of (0.9981) and molar absorptivity 1.9×104 L.mol-1.cm-1 . The limit of detection (LOD) and the limit of quantification (LOQ) are 0.0633 and 0.0847 ?g.mL-1 , respectively . Under optimum conditions,the stoichiometry of the reaction between bismuth (III) and arsenazo(III) r
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