Background:
Angiogenic potential m most tumors; characterized by VEGF and vascular bed density around tumor islands, is believed to be an important marker in predicting tumor growth,
recurrence and metastasis.
Materials and Methods:
The study included 50 cases of ameloblastomas. From each case 4 μm sections were stained IHC with antivascular endothelial growth factor antibody- and endothelial lined
vessels anti CD34 antibody to evaluate their expression and intensity in relation to their Fac Med Baghdad clinicopathological features.
Results:
Generally, VEGF was significantly highly expressed with strong intensity in outer cell layer of tumor islands, and the newly formed blood vessels were significantly
predominantly rounded and small in size in comparison to dental folicale and papilla of tooth germ. Young aged patients (≤ 20yrs) had highest mean MvD around tumor islands
(35.9). Regarding WHO classification; follicular, plexiform and lining cells in UAB had higher expression then acanthomatous and types, but 67% of those in plexiform were of
moderate intensity. There was no significant differences in mean MvD in all histological solid subtypes, and characterized by round and small vessels. Except those in plexiform,
they were elongated and medium. UAB had significant lower microvessel count around lining tumor cells (but not around mural growth) and more percentage of elongated medium
sized vessels than follicular but less than plexiform. There was significant correlation between VEGF expression and the shape of microvessels. Considering different
morphological cellular pattern, basal cells showed the highest VEGF positivity and intensity (87.5).
Conclusions:
The present study indicate the usefulness of the VEGF expression and MvD in explaining the aggressive, locally invasive biological behavior of ameloblastoma. The high
angiogenic potential is enhancing tumor cell survival and the increase in the production of new blood vessels formation is facilitating tumor growth, and by time will enhance the
proliferation potential of the incompletely removed surviving tumor islands, so increasing the chance of ameloblastoma recurrence.
Bacopa monnieri L. (Scrophulariaceae), synoname is Herpestis monniera that provides bioactive compounds, especially triterpenoid saponins (Bacosides) which exhibits an important biological activities, like hypothyroidism, anticonvulsant, memory enhancing and antistress. Because there are no researches about B. monnieri L. plant that grow in Iraq, and there active compounds especially triterpenoid saponin (TS), and there effects. This study was detected the presence of (TS) in, and examined the cytotoxic and the antioxidant activity of these compounds in vitro. The study was included the extraction and identification of TS from the whole parts of B. monnieri L. by using three methods, and the best yield was analyzed by High Performance Liqui
... Show MoreThe pharmacist's role in the community is currently directed towards providing drug information and patient care rather than drug compounding and dispensing. Patient counseling is an essential skill for pharmacists. So as to improve the pharmacist role in the community and enhance the patient's education and counseling skills, many continuing education programs are established. The aim of this study is to assess the perceptions and tendency of community pharmacists in Iraq regarding patients counseling and continuing pharmacists’ educational programs.
The importance of the present work falls on the pitting corrosion behavior investigation of 304 SS and 316 SS alloys in 3.5 wt% of aqueous solution bearing with chloride and bromide anion at different solutions temperature range starting from (20-50)oC due to the pitting corrosion tremendous effect on the economic, safety and materials loss due to leakage. The impact of solution temperatures on the pitting corrosion resistance at 3.5wt% (NaCl and NaBr) solutions for the 304 SS and 316 SS has been investigated utilizing the cyclic polarization techniques at the potential range -400 to1000 mV vs. SCE at 40 mV/sec scan rate followed by the surface characterization employing Scanning Electron&nbs
... Show MoreBackground: The evaluation and staging of renal cell carcinoma (RCC) has dramatically changed with the introduction of cross-sectional imaging. Nowadays, small renal lesions are easily detected by computed tomography (CT) examination while missed by other modalities.
Objective: To determine whether ultrasound (US) or CT scan is the optimum imaging modality for the evaluation of the renal masses.
Patients and methods: This is a comparative study in which 30 patients with hematuria were attending the urological consulting clinic in Ghazzi Al-Harriry hospital, Baghdad, Iraq from May 2016 to July 2017 were subjected to abdominal US and CT scan.
Results:
... Show MoreThe target of this study was to study the natural phytochemical components of the head (capsule) of Cynara scolymus cultivated in Iraq. The head (capsule) of plant was extracted by maceration in70% ethanol for 72 hours, and fractioned by hexane, chloroform and ethyl acetate. Preliminary qualitative phytochemical screening was performed on the ethyl acetate fraction for capsule was revealed the presence of flavonoid and aromatic acids. These were examined by (high -performance liquid chromatography) (HPLC diodarray), (high- performance thin-layer chromatography)(HPTLC).
Flavonoids were isolated by preparative layer chromatography and aromatic acid was isolated by preparative high-
... Show MoreDesert truffle is considered as a type of Syrian wild fungi that spreads heavily, and it occupies important rank in folk medicine, where its aqueous extract is used for the treatment of some eye and skin illnesses, and people prefer the use of black truffle. This work interested in studying of the most available species; Terfezia claveryi (black) and Tirmania pinoyi (white). The extracts of the two species of truffle were prepared by maceration with water, methanol, and ethanol 70%. Their total phenolic contents (TPC) and total flavonoid contents (TFC) were analyzed using Folin-ciocalteu and Aluminum chloride methods respectively, and their antioxidant activities was tested using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and
... Show MoreIn the present work, the nuclear shell model with Hartree–Fock (HF) calculations have been used to investigate the nuclear structure of 24Mg nucleus. Particularly, elastic and inelastic electron scattering form factors and transition probabilities have been calculated for low-lying positive and negative states. The sd and sdpf shell model spaces have been used to calculate the one-body density matrix elements (OBDM) for positive and negative parity states respectively. Skyrme-Hartree-Fock (SHF) with different parameterizations has been tested with shell model calculation as a single particle potential for reproducing the experimental data along with a harmonic oscillator (HO) and Woods-Saxo
... Show MoreThe concept of rehabilitation provided an essential richness in the conservation philosophy through sustaining buildings life and adapting them to the contemporary use through a vision which looks at the present and future . In Iraq , the existence of historical buildings and the traditional fabric in the cities required the urban development which enhanced the interests of planning and architectural fields especially the building rehabilitation which requires the architectural intervention , and all that led to elaborate the problem of research which is " The confusion in the concepts of monumental, historical and traditional buildings in Iraq, As well as The insufficient knowledge about rehabilitation and the acts related to it through
... Show MoreTwo simple, rapid, and useful spectrophotometric methods were suggest or the determination of sulphadimidine sodium (SDMS) with and without using cloud point extraction technique in pure form and pharmaceutical preparation. The first method was based on diazotization of the Sulphdimidine Sodium drug by sodium nitrite at 5 ºC, followed by coupling with α –Naphthol in basic medium to form an orange colored product . The product was stabilized and its absorption was measured at 473 nm. Beer’s law was obeyed in the concentration range of (1-12) μg∙ml-1. Sandell’s sensitivity was 0.03012 μg∙cm-1, the detection limit was 0.0277 μg∙ml-1, and the limit of Quantitation was 0.03605μg
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