Background:
Angiogenic potential m most tumors; characterized by VEGF and vascular bed density around tumor islands, is believed to be an important marker in predicting tumor growth,
recurrence and metastasis.
Materials and Methods:
The study included 50 cases of ameloblastomas. From each case 4 μm sections were stained IHC with antivascular endothelial growth factor antibody- and endothelial lined
vessels anti CD34 antibody to evaluate their expression and intensity in relation to their Fac Med Baghdad clinicopathological features.
Results:
Generally, VEGF was significantly highly expressed with strong intensity in outer cell layer of tumor islands, and the newly formed blood vessels were significantly
predominantly rounded and small in size in comparison to dental folicale and papilla of tooth germ. Young aged patients (≤ 20yrs) had highest mean MvD around tumor islands
(35.9). Regarding WHO classification; follicular, plexiform and lining cells in UAB had higher expression then acanthomatous and types, but 67% of those in plexiform were of
moderate intensity. There was no significant differences in mean MvD in all histological solid subtypes, and characterized by round and small vessels. Except those in plexiform,
they were elongated and medium. UAB had significant lower microvessel count around lining tumor cells (but not around mural growth) and more percentage of elongated medium
sized vessels than follicular but less than plexiform. There was significant correlation between VEGF expression and the shape of microvessels. Considering different
morphological cellular pattern, basal cells showed the highest VEGF positivity and intensity (87.5).
Conclusions:
The present study indicate the usefulness of the VEGF expression and MvD in explaining the aggressive, locally invasive biological behavior of ameloblastoma. The high
angiogenic potential is enhancing tumor cell survival and the increase in the production of new blood vessels formation is facilitating tumor growth, and by time will enhance the
proliferation potential of the incompletely removed surviving tumor islands, so increasing the chance of ameloblastoma recurrence.
Emotional exhaustion considered one of the critical factors in the formation and composition of organizational behavior of individuals within organizations, as well as social behavior and psychological, and emotional exhaustion is one of the three components of burnout, as well as depersonalization (cynicism) and low achievement, the emergence of research relevant to this concept began at the beginning of the seventies of the twentieth century, then started to become clear features in the eighties it. This research aims to build intellectual framework for draining emotional exhaustion through highlight on most important philosophical contents, as well as review and analysis of some models associated with this concept, and then a
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In The Name of Allah Most Gracious Most Merciful
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... Show MoreFoliar application and seed soaking has been used as a means of supplying supplemental doses of nutrients, plant hormones, stimulants, and organic components. the effects of these applications have included yield increases, and improved drought tolerance, and enhanced crop quality, so A field experiment was carried out during spring seasons in 2019 and 2020 for styding Seed soaking and Foliar Application of Ascorbic acid, Citric acid and Humic acid on Growth, Yield and Active Components IN Maize. Randomized complete block design in split plots arrangement was used with three replicates. Main-plots were for seeds soaking with ascorbic, citric (100 mg l-1) frequently and humic at (1 ml l-1). Sub-plots were for vegetative parts nutrition with
... Show MoreBackground: Brush cytology is an accepted technique that gets renewed interest. It is now used as an aid for the diagnosis and observation of possible epithelial changes that could be associated with oral mucosal diseases. This study aimed to evaluate the cytomorphometric changes in gingiva and buccal mucosa of type II diabetics and to assess their relation to oral symptoms and glycemic status. Materials and methods: Cytological Papanicolaou stained smear were prepared from cheek and gingiva of 20 non treated cases, 20 treated diabetics and 20 healthy persons of both sex after measuring their HbA1c and recording their oral symptoms. Hundred unfolded epithelial cells were evaluated qualitatively using MCID software to measure nuclear and cy
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