Background: Ulcerative colitis is a chronic idiopathic inflammatory disorder that affects the rectum & extends proximally to affect variable extent of the colon. Autoimmune hemolytic
anemia had reported in few cases.
Objective: to determine the prevalence of autoimmune hemolytic anemia in Ulcerative colitis.
Patient & Methods: Fifty Iraqi patients having Ulcerative colitis attending the GIT Center in Baghdad during the period from March to August 2004 were interviewed, examined and
diagnosed according to pathological study done for colonic biopsies by the same centre. Blood was drown for the assessment of complete picture with blood film, reticulocyte
percent, erythrocyte sedimentation rate, Coombs test (direct, indirect), antinuclear antibody, immunoglobulin assay, serum iron and TIBC in the same laboratory unit.
Results: In our study, 18(36%) patients were anemic, fifteen of them had normal or low reticulocyte percent with normochromic normocytic RBC in blood film, probable causes of
anemia was either iron deficiency proved by low serum iron and high total iron binding capacity (TIBC), or anemia of chronic illness. The remaining three of eighteen patients with
reticulocytosis, two of them Coombs test were negative and normal film, but they were having acute bloody diarrhea which probably was the cause of reticulocytosis.
The third patient was Coombs positive with features of hemolytic anemia in the blood film (polychromic with spherocytosis), this patient had also a high titer of IGg, LDH, so that this
female had all the evidence of autoimmune hemolytic anemia which is a rare complication of Ulcerative colitis. Salfasalazine as a treatment of Ulcerative colitis can cause autoimmune haemolysis, but in this case the drug had stopped for one month before the development of autoimmune haemolysis. In our sample we had five patients with reticuloytosis but normal haemoglobin level and normal blood film with cooms negative (direct and indirect) those five patients might had nonimmune causes of hemolytic like G6PD deficiency which need further investigations, or might had bloody diarrhea which cause elevated reticulocyte as areaction to blood loss, or it may be due to salazopyrine effect which may lead to increase level of reticulocyte.
Conclusion:Most studies giving range of autoimmune haemolytic anaemia with Ulcerative colitis between 1%-2%, all these studies showed direct coomb's test positive, and our study
showed 2% incidence. So it is one of the rare manifestations of Ulcerative colitis. It does not depend much on severity, duration and degree of colonic involvement.
Background: Neudesin is a peptide secreted in brain and adipose tissues that has neural and metabolic functions. Its role as regulator of energy expenditure leads to assumption that its level may be regulated depending on thyroid gland pathology. Objective: This study aimed to investigate serum neudesin levels in patients with thyroidism and to evaluate1 any possible relationship between plasma neudesin levels and thyroid hormone levels. Methods: The study included 100 women with newly diagnosed thyroidisim were subdivided into two groups: hyperthyroidism group (50 female patients with age ranged from 18 to 60 years) and hypothyroidism group (50 female patients with age ranged from 18 to 75 years). A control group (30 healthy females with a
... Show MoreSource, sedimentation, coagulation, flocculation, filter, and tank are parts of a water treatment plant. As a result, some issues threaten the process and affect the drinking water quality, which is required to provide clean drinking water according to special standards and international and local specifications, determined by laboratory results from physical, chemical, and biological tests. In order to keep the water safe for drinking, it is necessary to analyze the risks and assess the pollution that occurs in every part of the plant. The method is carried out in a common way, which is monitoring through laboratory tests, and it is among the standards of the global and local health regulators
In this study, NaOH dissolution method was applied to dissolve cellulose fibers which extracted from date palm fronds (type Al-Zahdi) taken from Iraqi gardens. In this process, (NaOH)-solution is brought into contact with the cellulose fibers at low temperature. Experiments were conducted with different concentrations of NaOH (4%, 6%, 8% and12%) weight percent at two cooling bath temperatures (-15 oC) and (-20oC). Maximum cellulose dissolution was 23 wt% which obtained at 8 wt% concentration of NaOH and at cooling bath temperature of -20oC. In order to enhance the cellulose fibers dissolution, the sample was pretreated with Fenton's reagent which consists of hydrogen peroxide (H2O2), oxalic acid (C2H2O4) and ferrous sulfate (FeSO4). This
... Show MoreWisdom in the era before Islam is soo famous and so mature And Wisdom in the age of Islam {the holy quran and AI Hadeeth AI shareef }is dealt with by different meanings that agree with the contexts in which it occurs its contacs One of meanings is wisesaying that occuars in the Halal and Haram .As to the wisdom of the Amawy age ,it was some times absent since it was not dealt with by the great Poets of that age .In the Poetry of AL-FARAZDAK , Wisdom was little and it expressed religious and phsycological meanings because wisdom is amessage that has along –rang .
The study includes the epipelic algae in Hemren reservoir, for the period between Januarys to October 2000 .The samples were collected from three selected sites at north, middle and south of reservoir. A total of 96 taxa of epipelic algae were identified. The diatoms were the dominated by 82 taxa represented 85.4% of the total identified species, followed by blue-green algae (cyanophyta) of 6.3 taxa (6%), and then green algae (chlorophyta) of 5.2 taxa (5%). One species was recorded for each crysophyta, euglenophyta and pyrrophyta. The seasonal variation for the cell density showed two peaks during spring and autumn seasons. Few species were dominated during the most studied period such as Achnanthes minutissima, Navicula cryptocephala
... Show MoreA LiF (TLD-700) PTFED disc has adiameter of (13mm) and thickness of (0.4mm) for study the response and sensetivity of this material for gamma and beta rays by using (TOLEDO) system from pitman company. In order to calibrate the system and studying the calibration factor. Discs were irradiated for Gamma and Beta rays and comparing with the theoretical doses. The exposure range is between 15×10-2 mGy to 1000×10-2 mGy. These doses are within the range of normal radiation field for workers.