Background: The plant (Khat) contains at least 40 types of alkaloids. It has an adrenergic like effect especially on the heart one of these alkaloid is cathedulins group which has molecular height of 600- 1200mm.I/L. it is used frequently mainly at the African horn region (e.g. yemen). This plant alkaloids used by people in form of bands (each band is about 50gm, two bands 100gm and so on).
Patients and methods: Three groups of Patients have been included in this study. Group A: (30) patients with dilated cardiomyopathy, Group B: (50) patients with history of ischemic heart disease with clinical presentation of ischemic cardiomyopathy and Group C: (80) cases (50 cases of ischemic cardiomyopathy, 30 cases dilated cardiomyopathy). Used as control group to see the difference from stopping the Khat without adding any medication during the follow up peroid this was over a year with monthly checkup. The place of this was Yemen-Sannaa general hospital and Sannaa private international clinic.
Results: This study showed that the age range of patients and volunteers was similar, mean age (35- 65 years), all were male because this plant is used by most of the males and there was difficulty in discussing this problem with the female these three groups were categorized into two groups according to the amounts of all khat bands consumed. Group1: people using about 50gm of this plant and did comprise 75% of all the cases. Group2: people using about 50-150gm of this plant and comprising 25% of all the cases. This study did not show any significant correlation between the incidence of dilated cardiomyopathy and the chronic use of this plant alkaoild, also there was no correlation between the duration of using this alkaloid and probability of getting these cardiac disorders. Stopping consuming this alkaloid did not change the clinical feature dramatically except reduction of liver enzymes elevation.
Conclusion: No significant correlation between using the plant khat and development of ischemic and non ischemic dilated cardiomyopathy.
The research examines the extent to which government spending decisions can affect the level of the financial performance of the directorate. The research problem was based on the financial reality of the Directorate of Sewerage of Diyala province. Spending on the Directorate of the research area. To achieve a set of objectives: indicate the impact of government spending decisions on financial performance, the use of financial analysis to assess the performance of the Directorate. The research adopted financial analysis tools, a set of financial ratios, through which the spending decisions taken by the Directorate of the field of research will be evaluated, and during the period (2014-2018). The research also adopted statistical
... Show MoreThe purpose of this study is to investigate the capability of bacterial DNA compared to bacterial lysate in stimulating arthritis using rat model. One hundred mid-stream urine specimens were collected during November 2012 to January 2013, from patients suffering from urinary tract infections attending hospitals in Baghdad, Iraq. Susceptibility of Staphylococcus aureus isolates to antibiotics was examined. Twenty five isolates were identified as S. aureus and they developed multi drug resistance. S. aureus S1 lyaste and its DNA were intra-articulary injected in rats. The levels of IL-6, anti-ds DNA Ab and leukocytes count were measured. In general, IL-6, anti-ds DNA Ab and leukocytes count were significantly higher in sera of rats injecte
... Show MoreA simple, fast, and sensitive batch and flow injection spectrophotometric
methods have been developed for the determination of clonazepam(CZP) in pure
form and in pharmaceutical preparations. The proposed methods are based on the
oxidative coupling reaction of the reduced clonazepam using Zn powders and conc.
HCl with payrocatechol and in the presence of ferric sulphate. The resulting reddish
colored product had a maximum absorbance at 515 nm. The optimum reaction
conditions and other analytical parameters have been evaluated . The linear ranges
for the batch and FI methods determination of CZP were 0.5-32, 50-400 μg mL-1
and the detection limits were 0.193, 22.60 μg mL-1 for both methods respectively.
Statis
Background: Growth hormone has multiple effects on the overall form and function of growing body. Aside from these growth stimulating functions, it has marked effects on energy metabolism, it acts on fat cells to reduce the amount of stored fats, promotes protein synthesis in cells and plays a role in regulating the sugar levels in the blood.
Objective: to investigate the effect of growth hormone replacement on lipid profile, insulin level, glucose and calcium level in patients with growth hormone deficiency (GHD).
Method: A prospective study of 49 children; 37 boys and 12girls with a mean age(13.5±3.3)years attending the Children Welfare Te
... Show MoreThis study aimed to identify attitudes towards mental illness in pregnant female clients to clinics women in the province of Ramallah and Al Bireh, for this purpose applied to study procedures on a sample of (200) of pregnant mothers were selected a sample available, have reached results no statistically significant differences in the level of attitudes towards mental illness due to the variable age in mothers pregnant female clients to clinics for women. Ther were astatistically significant differences in the level of these trends depending on the variable-level scientific research for the benefit of pregnant class university students and older and then high school and so on all areas except the area of social interaction, The results a
... Show MoreBackground: One of the most common complications of dentures is its ability to fracture, so the aim of this study was to reinforce the high impact denture base with carbon nanotubes in different concentrations to improve the mechanical and physical properties of the denture base. Materials and methods: Three concentrations of carbon nanotubes was used 0.5%, 1%, 1.5% in a pilot study to see the best values regarding transverse strength, impact, hardness and roughness test, 1 wt% was the best concentration, so new samples for control group and 1wt% carbon nanotubes and the previous tests were of course repeated. Results: There was a significant increase in impact strength and transverse strength when we add carbon nanotubes in 1wt%, compared
... Show MoreSwimming has now become the focus of attention of specialists, which has led to the search for the best methods and various methods of training, which rely heavily on scientific research and studies, through the use of proper planning and a comprehensive scientific and practical vision in the preparation and training process for this game. Some studies have proven that The use of training methods has a positive role in the athletic training of the swimmer, provided that these methods are used in the correct way according to the scientific principles of training and with the loads and stresses that serve the specialized activity, i.e. the swimming distance. The study aimed at the follow 1- Preparing exercises using elastic ro
... Show MoreEndothelin-1 (ET-1) is a potent vasoconstrictor hormone that has been identified as an important factor
responsible for the development of cardiovascular dysfunctions. ET-1 exerts its vasoconstrictor activity
through two pharmacologically distinct receptors, ETA and ETB that are found in vascular smooth muscle
cells (VSMCs) and the vasodilator activity through an ETB receptor located on endothelial cells. This study
aimed to show the impact of 1µM L-arginine (LA), 100µM tetrahydrobiopterin (BH4), and their combined
effect on ET-1 activity in both lead-treated and lead-untreated rat aortic rings. This means, investigating how
endothelial dysfunction reverses the role of nitric oxide precursor and cofa
The objective of this study was to determine the concentration of trace element chromium(III) and thyroid peroxidase activity in human serum , and to find a relationship between the concentration of chromium(III) and thyroid peroxidase activity in serum of patients with hypothyroidism, hyperthyroidism and healthy subjects. Serum thyroid peroxidase was measured by enzyme linked radioimmunoassay(ELISA) method and chromium determination was by atomic absorption spectrophotometer .Comparing the values of chromium concentration and thyroid peroxidase activity in both samples showed that there were significant positive correlations between chromium levels and thyroid peroxidase activity(P<0.01, r=0.11).
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