Background: Palmoplantar psoriasis is a therapeutically challenging condition that can significantly impact patient quality of life as it directly affects activities. However, despite this impact, few clinical studies address treatment. Herbs and their extracts have been used for treatment of skin disease for centuries. One of the most popular herbs in our society is black cumin or seed of blessing oil (Nigella Sativa); this plant had diverse clinically useful activity.
Patients and Methods: This study was conducted in the Department of Dermatology and Venereology in Baghdad Teaching Hospital, Iraq during the period between January and October 2003. In this singleblind randomly controlled therapeutic study, thirty patients were enrolled, their ages ranged from 22-65 years. There were 18` females and 12 males. The patients were divided into 2 groups; group A (20 patient) instructed to use nigella sativa 10% ointment twice daily for 3 months, while group B (10 patient) used a control ointment(Vaseline) . Statistical analyses were carried out by computer using ttest, and chi-square when needed.
Results: twenty-four patients completed the study. In group A (18 patients), we noted a significantly reduction of the thickness and fissuring of the skin of the affected part which was also become very soft after 3 months of therapy. The response of patients to treatment was good in 50%, moderate in 27.8% and mild response in 22.2%. The satisfaction of patients with treatment was full in 61.1%, partial in 27.8%, and no satisfaction in 11.1%. In group B (6 patients), the lesions showed no significant reduction after 3 months and the response of patients to treatment was good in 16.6%, moderate in 33.4%, and mild response in 50%. The satisfaction of patients with treatment in this group was full in 16.6%, partial in 50%, and no satisfaction in 33.4%. The difference in outcome after 12 weeks between the 2 study groups was statistically significant.
Conclusion: The ointment of the black cumin is considered as a very good remedy for the palmoplantar psoriasis. This remedy is considered to be very safe, cheap and easy to prepare with no serious side effects as compared to the previous ointments for this type of psoriasis.
The study is focused on the modification of the standardized newspaper with natural polymers chitosan and keratin hydrolysate applied on the paper surface from polymer solution. This modification is based particularly on the formation of the complexes between acidic surface groups on cellulose fibers and the natural polymers which improved the mechanical properties of the paper and the positive results which were observed particularly in folding endurance of the newspaper.
An ingrowing toenail is a common problem affecting mainly adolescents and young adults, with a male predominance of 3:1. The disorder generally occurs in big toes. It is painful and often chronic and it affects work and social activities. Most patients initially complain of pain and later discharge, infection and difficulty in walking occur. The Objectives: The purpose of the study was to evaluate the efficacy and safety of (10600nm) CO2 laser in the treatment of ingrowing toe nail. Patients, Materials & Methods: This study was done in laser medicine research clinics from July 2013 to the end of December 2013; 10 patients including 7(70%) males and 3 (30%) females with age ranging from 18 years to 70 years with mean age of 44 years o
... Show MoreIn this paper, a discrete SIS epidemic model with immigrant and treatment effects is proposed. Stability analysis of the endemic equilibria and disease-free is presented. Numerical simulations are conformed the theoretical results, and it is illustrated how the immigrants, as well as treatment effects, change current model behavior
In this article, new Schiff base ligand LH-prepared Mn(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II), Hg(II), Pd(II), and Pt(II) materials were analyzed using spectroscopy (1 Metal: 2 LH). The ligand was identified using techniques such as FTIR, UV-vis, 1H-13C-NMR, and mass spectra, and their complexes were identified using CHN microanalysis, UV-vis and FTIR spectral studies, atomic absorption, chloride content, molar conductivity measurements, and magnetic susceptibility. According to the measurements, the ligand was bound to the divalent metal ions as a bidentate through oxygen and nitrogen atoms. The complexes that were created had microbicide activity against two different bacterial species and one type of fungus. DPPH techniques were bei
... Show MoreA new ligand (H4L) and its complexes with ( ZnII, CdII and HgII) were prepared. This ligand was prepared in two steps. In the first step a solution of terephthaldehyde in methanol was reacted under reflux with 1,2-phenylenediamine to give an precursor compound which reacted in the second step with 2,4-dihydroxybenzaldehyde to give the ligand. The complexes were then synthesized by direct reaction of the corresponding metal chloride with the ligand. The ligand and complexes were characterized by spectroscopic methods FT-IR, UV-Vis, 1HNMR, and atomic absorption, chloride content, HPLC, mole-ratio determination. in addition to conductivity measurement. The data of these measurements suggest a distorted tetrahedral g
... Show MoreThis research aims to predict new COVID-19 cases in Bandung, Indonesia. The system implemented two types of deep learning methods to predict this. They were the recurrent neural networks (RNN) and long-short-term memory (LSTM) algorithms. The data used in this study were the numbers of confirmed COVID-19 cases in Bandung from March 2020 to December 2020. Pre-processing of the data was carried out, namely data splitting and scaling, to get optimal results. During model training, the hyperparameter tuning stage was carried out on the sequence length and the number of layers. The results showed that RNN gave a better performance. The test used the RMSE, MAE, and R2 evaluation methods, with the best numbers being 0.66975075, 0.470
... Show MoreObjective: Synthesized a series of new thiourea (TU) derivatives, tested their antioxidant activity, and investigated their expected biological activity by theoretical study (computational methods). Methods: The derivatives were made using a one-pot reaction with two steps. Initially, succinyl chloride was mixed with KSCN to make succinyl isothiocyanate. Then, primary and secondary amines were used to make TU derivatives. The theoretical studies were done by Swiss ADME and molecular docking via Genetic Optimization of Linkage Docking (GOLD). Then evaluate antioxidant activity using the DPPH scavenging method. Results: FT-IR, 1H NMR, and 13C NMR spectroscopy show the verification of all the prepared derivatives. Compounds (II), (VIII),
... Show MoreThe Battle of Kadesh is replete with many military arrangements that reflect the tremendous development of war preparations in the thirteenth century BC; where the expressive pictures the Egyptians left on some of the walls of their temples show the tremendous ability to organize and divide the forces and the great development that affected the war machine. Furthermore, the text accompanied these pictures reveal some news about that battle, which is considered one of the most important wars in the ancient world. Thus, the importance of the study lies in the fact that it examines one of the most important battles of the ancient Near East, the results of which had great repercussions on the region. This is because it is the most abundant B
... Show MoreA new ligand complexes have been synthesis from reaction of metal ions of MnII , CoII , NiII , CuII , ZnII , CdII and PdII with schiff base [(E)-1-((2-amino-5-(3, 4, 5-trimethoxybenzyl) pyrimidin-4-ylimino) methyl) naphthalen-2-ol [HL)]. The prepared [HL] was characterized by FT-IR, UV-Vis spectroscopy, 1H13CNMR spectra Mass spectra and melting point. The compounds were characterized by techniques UV-Vis and FT-IR spectral studies, micro analysis (C.H.N), determination of atomic absorption, chloride content, molar conductivity measurements, magnetic susceptibility and melting point. The ligand acts as a monobasic tridentate, coordinating through deprotonated phenolic O and azomethine N atoms. The compounds are neutral electrolytic in dimeth
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