Schizophrenia (SZ) is severe mental disorder and characterized by fundamental disturbances in thinking, perception and emotions. Immune deregulation has been postulated to be one of the mechanisms underlying the pathogenesis of schizophrenia. This study hypothesized that interleukins would have a link with schizophrenia patients. The serum IL-2 and IL-10 levels were examined by enzyme-linked immunosorbent assay (ELISA) in schizophrenia patients (n=60) and healthy controls (n = 30). The results showed that serum IL-2 and IL-10 levels were significantly different among schizophrenia patients. The observations indicate a significant decrease (P < 0.05) in schizophrenic patients serum levels of IL-2 compared with healthy control. Whereas detection of IL-10 in the schizophrenic patients serum showed significantly increase level (P < 0.05) compared with healthy control. The results supported that immune disturbance is related to the schizophrenia patients and might play an important role in the pathophysiology of schizophrenia.
Altered IL-2 and IL-10 serum levels in schizophrenic patients
Schizophrenia
IL-2
IL-10
ELISA
Publication Date
Thu Apr 27 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
On A Bitopological (1,2)*- Proper Functions
(1
2)*-proper functions
(1
2)*-perfect functions
(1
2)*-compact functions
(1
2)*-cluster points
(1
2)*- 2 T -spaces
(1
2)*-compactly closed sets and (1
2)*-K-spaces .
In this paper, we introduce a new type of functions in bitopological spaces, namely, (1,2)*-proper functions. Also, we study the basic properties and characterizations of these functions . One of the most important of equivalent definitions to the (1,2)*-proper functions is given by using (1,2)*-cluster points of filters . Moreover we define and study (1,2)*-perfect functions and (1,2)*-compact functions in bitopological spaces and we study the relation between (1,2)*-proper functions and each of (1,2)*-closed functions , (1,2)*-perfect functions and (1,2)*-compact functions and we give an example when the converse may not be true .