Preferred Language
Articles
/
ijs-9879
Electrochemical Study for the Effect of Simvastatin and Atorvastatin on Coenzyme Q10 by Differential Pulse Polarography Using Mercury Drop Electrode
...Show More Authors

Statin drugs act by inhibiting the enzyme HMG-CoA reductase which is responsible for manufacture of cholesterol and the biosynthesis essential energy production Co-factor (Coenzyme Q10). The aim from this research includes study the effect of statin drugs (Simvastatin and Atorvastatin) on the Coenzyme Q10 using differential pulse polarographic technique at a dropping mercury electrode (DME) and in a mixture of [4:1] methanol-phosphate buffer of pH7.0 as supporting an electrolyte. Prior to this, the behaviors of Simvastatin, Atorvastatin and Coenzyme Q10 were studied separately in their solvents. The half-wave potential (E1/2) of Co Q10 were -0.31volt and -1.37Volt, -1.33 Volt for simvastatin and atorvastatin respectively. A mixture of Coenzyme Q10 with Simvastatin and Atorvastatin in the same solvent shows a shift in their peak potential (Ep) toward more negative potentials values by (-0.06volt) for Simvastatin and by (-0.09volt) by Atorvastatin.

View Publication Preview PDF
Quick Preview PDF
Publication Date
Thu Nov 21 2019
Journal Name
Al-kindy College Medical Journal
Magnetic Resonance Venography Findings In A Group Of Patients With Multiple Sclerosis
...Show More Authors

Background: Multiple sclerosis is a chronic heterogeneous demyelinating axonal and inflammatory disease involving the Central Nervous System [CNS] white matter with a possibility of gray matter involvement in which the insulating covers of nerve cells in the brain and spinal cord are damaged. This damage disrupts the ability of parts of the nervous system to communicate, resulting in a wide range of signs and symptoms. Cerebral venous insufficiency theory was raised as a possible etiology for the disease at 2008 by Zamboni an Italian cardiothoracic surgeon. This theory was defeated by Multiple Sclerosis[ MS] researchers and scientists who thought that the disease is an autoimmune rather than vascular.

Obj

... Show More
View Publication Preview PDF
Crossref
Publication Date
Thu Jun 30 2022
Journal Name
Iraqi Journal Of Science
Radioactivity Levels in Water Samples of Tigris River in Baghdad City, Iraq
...Show More Authors

   The natural radioactivity levels in water samples along the Tigris river (one of the major rivers of the world) within Baghdad city were investigated to determine and evaluate the radioactivity risks in the water of the river. The specific activity of the radionuclides (238U, 232Th, 40K, and 137Cs) for thirty different water samples from Tigris river within Baghdad city were measured using gamma-ray spectrometer, employing a NaI(Tl) scintillation detector. The results showed that the average value of the specific activity for 238U, 232Th, 40K, and 137Cs were (24.20, 16.70, 329.22, and 19.40) Bq/l, respectively. The calculated average annual effec

... Show More
View Publication Preview PDF
Scopus Crossref
Publication Date
Thu Mar 30 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Formulation of Metoprolol Bilayer Tablets as an Oral Modified Release Dosage Form
...Show More Authors

Metoprolol is a β1 adrenergic blocker used in treatment of heart diseases. Metoprolol (100mg) tablets was formulated as a modified release oral system utilizing the concept of bilayer system, first layer contained (30mg) as immediate release and the other (70mg) in the sustained release matrix.  The immediate release layer consisted of lactose or microcrystalline cellulose as diluents with sodium starch glycolate or sodium croscarmellose as disintegrants. The result showed that the layer contains microcrystalline cellulose and 2% sodium starch glycolate gave disintegration time similar to that of conventional metoprolol tartrate tablet. This result was subjected in the subsequent preparation of the bilayer tablet. The

... Show More
View Publication Preview PDF
Crossref
Publication Date
Tue Jul 30 2024
Journal Name
Iraqi Journal Of Science
Diversity of Hard Ticks (Acari, Ixodidae) Infestion in Arabian Camel in Iraq
...Show More Authors

      A total of 1346 hard ticks (863♂ and 483 ♀) infested 104 camels, 60 alive camels with 93.33%  infestation rate and 44 carcasses of camels had 79.54% infestation rate The total infestation rate was 87.5 %. The current study results revealed ten species of hard ticks family Ixodidae Koch, 1844 related to genus Hyalomma as following: H. dromedarii Koch, 1844, H. schulzii Morel, 1969, H. turanicum Pomerantsev, 1946, H.  excavatum Koch, 1844, H. truncatum Koch, 1844, H. scupense Schulzii, 1919, H. marginatum Koch, 1844, H. anatolicum Koch, 1844, H. rufipes Koch, 1844, H. impeltatum Schulze & Schlottke, 1930 from camel Camelus dromedarius Linnaeus, 1758 collected from 21 regions belonging to six provinces in middle, w

... Show More
Scopus Crossref
Publication Date
Wed May 01 2019
Journal Name
Iraqi Journal Of Science
Detection of Sabin Poliovirus Serotypes among Vaccinated Iraqi Children with AFP Syndrom
...Show More Authors

Poliomyelitis is a viral disease caused by an enterovirus known as poliovirus and is well known for its role in causing paralysis in children, the virus is only infectious in humans and does pass into the central nervous system and cause various degrees of paralysis, poliovirus passes newcomer disabuse of suppliant to alms-man thumb the fecal-oral route infected persons still shed the virus in their stool allowing the virus to infect others. The main aim of this study was isolating and differentiation of poliovirus strains (Sabin virus) from the stool samples of children received polio vaccine TOPV and suffering from acute flaccid paralysis.

In this study use the cell culture system as the

... Show More
View Publication Preview PDF
Publication Date
Wed Jul 05 2017
Journal Name
International Journal Of Science And Research (ijsr)
Hyperglycosylated hCG in a Group of Iraqi Patients with Gestational Trophoblastic Disease
...Show More Authors

Background : Hyperglycosylated hCG a newly discovered variant of hCG which can be used as a predictor of invasion of trophoblastic cells in patient with gestational trophoblastic disease. Objectives : To measure hyperglycosylated human chorionic gonadotrophin and to assess how far it can be used as predictor of invasion in invasive mole and choriocarcinoma. Study design control study. Setting: : Case Gynecological department in Baghdad Teaching Hospital from January 2016 to January 2017. Patient and Methods : 60 women were enrolled in this study 30 of them were with gestational trophoblastic disease (no.= 30 ) the remainder were normal pregnancy (no. =30) , hCG –H level was measured in both groups. Results : Mean serum hCG-H le

... Show More
View Publication Preview PDF
Crossref (1)
Crossref
Publication Date
Sun Dec 30 2012
Journal Name
Al-kindy College Medical Journal
Incidence of Renal Injuries in Abdominal Trauma at Al-Kindi Teaching Hospital
...Show More Authors

Background : The kidneys may be injured in abdominal trauma, both blunt & penetrating. Renal trauma may manifest in a dramatic fashion for both the patient and the clinician. Objectives: To evaluate the incidence, management, morbidity &mortality of renal injury in blunt & penetrating abdominal trauma.
Results:The majority o f patients were males (35= 77.8%), the rest were females (10= 22.2%). The average age was 37 years (range= 18-56 years). The most common grades were grade1, grade2 and grade3 (40=88.9%), while 5 patients (11.1%) were grades 4 and 5.The most common associated injuries were liver, spleen, small & large bowels and diaphragm. The mortality was 20% (9 patients). The most common cause of death was multip

... Show More
View Publication Preview PDF
Publication Date
Wed Aug 30 2023
Journal Name
Iraqi Journal Of Science
Selective Extraction of Metformin in Pharmaceutical Preparation via Synthesized MIP-SPE Techniqu
...Show More Authors

       This work demonstrates the synthesis and storage of molecular-imprinted polymers (MIP) at room temperature using bulk polymerisation of Metformin (Met) characterized by high sensitivity, low cost, and high stability. To ensure an acceptable adsorption capacity, the research employed 0.8:4:20 mmol ratios of template, monomer, and cross-linking agents for the polymerization. A functional monomer, 2-acrylamido-2-methyl-1-propane sulphonic acid C7H13NO4S, was cross-linked with N,N-methylene bisacrylamide C7H10N2O2 to form Met-MIP, which could be characterized using a UV-VIS spectrophotometer at 236 nm, FT-IR spectroscopy, and scanning electron

... Show More
View Publication Preview PDF
Scopus (1)
Scopus Crossref
Publication Date
Tue Jan 30 2024
Journal Name
Iraqi Journal Of Science
Machine Learning Based Crop Yield Prediction Model in Rajasthan Region of India
...Show More Authors

     The present study investigates the implementation of machine learning models on crop data to predict crop yield in Rajasthan state, India. The key objective of the study is to identify which machine learning model performs are better to provide the most accurate predictions. For this purpose, two machine learning models (decision tree and random forest regression) were implemented, and gradient boosting regression was used as an optimization algorithm. The result clarifies that using gradient boosting regression can reduce the yield prediction mean square error to 6%. Additionally, for the present data set, random forest regression performed better than other models. We reported the machine learning model's performance using Mea

... Show More
View Publication Preview PDF
Scopus (2)
Crossref (1)
Scopus Crossref
Publication Date
Sun Dec 25 2022
Journal Name
International Journal Of Drug Delivery Technology
Synthesis of Few New Carrier Polymers Derived from 2-hydrazinylbenzo[d]thiazole
...Show More Authors

2-hydrazinylbenzo[d]thiazole compound [1] is produced from reaction of 2-mercapto-benzothiazole with hydrazine hydride in ethanol. Compound [1] reacted with maleic anhydride in DMF to produce (Z)-4-(2-(benzo[d] thiazol-2yl) hydrazinyl)-4-oxobut-2-enoic acid [compound (2)]. While the treatment of compound [2] with the ammonium persulfate (NH4)2S2O8 (as the initiator) in order to produce compound [3], then compound [3] reacted with thionyl chloride in benzene to produce compound [4], finally compound [4] reaction with various drugs: cephalexin, amoxicillin, sulfamethizole, elecoxib obtained polymers [5–8]. The structure of synthesized compounds identified by spectral data: fourier transform infrared (FTIR) and proton nuclear magneti

... Show More
View Publication Preview PDF
Scopus (1)
Crossref (1)
Scopus Crossref