Preferred Language
Articles
/
ijs-7538
Genetic Polymorphisms of Interleukin -1 beta Gene in Association with Multiple Sclerosis in Iraqi Patients
...Show More Authors

Interleukin-1 β (IL-1 β) is considered to be one of the most important mediators in the pathogenesis of inflammatory diseases, particularly in neurodegenerative diseases such as multiple sclerosis (MS). MS is a chronic inflammatory disease characterized with demyelination in central nervous system (CNS). There was believe that single nucleotide polymorphisms (SNPs) in IL-1β gene can alter the structure and function of the IL-1β and consequently may have play role in MS disease. In this this study the IL-1β gene polymorphism (rs16944, rs1143634) and their association with MS in Iraqi patients were investigated. Two SNPs including IL-1β-511 (rs16944) in promoter and IL-1B+3962 (rs1143634) in encoding region, were studied using Polymerase Chain Reaction- Sequence Specific Primer (PCR-SSP) technique. The results revealed that IL-1β-511 SNP has three genotypes (CC,CT, TT) with non- significant difference in the SNP genotype and allele frequencies of MS patients compare with control group, it was also noticed that the risk allele was (C) with relative risk (RR=1.55) and higher frequency (60.77%) than T (39.23%) allele in RRMS patients. On other hand the three genotypes (CC,CT, TT) of IL-1B+3962 SNP it seem to have the same picture, that mean there was no significant difference in their frequencies between RRMS patients and control group , and the highest genotype frequency was for (CC) genotype (68.92%) and the lowest frequency was for( TT) genotype (2.88%) in patients, it was also noticed that the risk allele was (C) with odd ratio (2.44) and that the (T) frequencies were (16.98%vs. 33.33%) while (C) frequencies were (83.02 vs. 66.67%) in patients and control group respectively. Concerning with these findings, one can suggest that interleukin-1β gene polymorphisms may not be relevant to susceptibility to MS in Iraqi patients, this is probably due to many reasons such as ethnic diversity, the relevant of haplotype for this gene with other haplotype of cytokine encoding genes and finally the limitation of sample size which play critical role in SNPs studies.

View Publication Preview PDF
Quick Preview PDF
Publication Date
Tue Sep 11 2018
Journal Name
Iraqi Journal Of Physics
Estimation of kidney tumor volume in CT images using medical image segmentation techniques
...Show More Authors

Kidney tumors are of different types having different characteristics and also remain challenging in the field of biomedicine. It becomes very important to detect the tumor and classify it at the early stage so that appropriate treatment can be planned. Accurate estimation of kidney tumor volume is essential for clinical diagnoses and therapeutic decisions related to renal diseases. The main objective of this research is to use the Computer-Aided Diagnosis (CAD) algorithms to help the early detection of kidney tumors that addresses the challenges of accurate kidney tumor volume estimation caused by extensive variations in kidney shape, size and orientation across subjects.
In this paper, have tried to implement an automated segmentati

... Show More
View Publication Preview PDF
Crossref
Publication Date
Mon Jan 20 2025
Journal Name
Journal Of Baghdad College Of Dentistry
Incidence of Cleft Lip and Palate in Al-Ramadi City (Descriptive Epidemiological Study)
...Show More Authors

Background Birth defects are one of the causes of pediatric disability and mortality in all around the world. Data on birth defects from population-based studies originating from developing countries are lacking. Cleft lip (CL), cleft lip and palate (CLP), and isolated cleft palate (CP), collectively termed oral clefts, occur in all races, both sexes, and all socioeconomic groups and vary internationally (1). The main aim of this research is to establish the frequency of cleft lip and/or palate in the population of the Al-Ramadi City, and to characterize the demographic features of affected individuals and find possible risk factors. Materials and methods We conducted a survey of the Educational Maternal and Pediatric Hospital in Al-Ramadi

... Show More
View Publication Preview PDF
Crossref (2)
Crossref
Publication Date
Tue Dec 29 2020
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Separation and Identification of Phenolic Acid from Borago officinalis (F:Boraginaceae) Cultivated in Iraq
...Show More Authors

    The plant Borago officinalis, which belongs to the Boraginaceae family and Celebrated as borage, is one of the useful medicinal plants cultivated in Iraq. It was used in olde medicine in Iraq, Irane, Syria and Europe for management of various diseases. It is commonly used as an atonic, tranquilliser, management of cough, sore throat, pneumonia, swelling, inflammatory diseases, antioxidant, and anticancer. This project provides the first comprehensive research done in Iraq to study the phytochemicals and the methods of extraction and isolation of active constituents from Borago officinalis cultivated in Iraq. The plant was harvested in spring from AL-Rifai, Nassiriyah city, IRAQ in February 2019.were w

... Show More
View Publication Preview PDF
Scopus (2)
Crossref (1)
Scopus Crossref
Publication Date
Sat Jun 19 2021
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Possible Protective Effects of Lutein against Ciprofloxacin Induced Bone Marrow Toxicity in Rats
...Show More Authors

Ciprofloxacin, which is a second generation of fluoroquinolone and one of the most effective and widely used drugs within fluoroquinolone. Unfamiliar adverse effects of ciprofloxacin such as bone marrow (BM) suppression, thrombocytopenia, anemia, agranulocytosis, renal failure, and others observed. Lutein, is a xanthophyll (an oxygenated carotenoid), was focused by most studies as it has a strong antioxidant activity in vitro; and also, it has been associated with reducing the risk of the age-related disorders. The current study was designed to describe the role of apoptosis through the measurement of Bcl-2 associated X protein (Bax) marker, as mechanisms of bone marrow toxicity induced by ciprofloxacin and to find whether lutei

... Show More
View Publication Preview PDF
Scopus (3)
Crossref (1)
Scopus Crossref
Publication Date
Wed Jan 01 2014
Journal Name
Journal Of The College Of Languages (jcl)
Females' Journey into Finding the Self in Beth Henley’s Crimes of the Heart
...Show More Authors

Writing as a female playwright in theatre gives a deeper depiction of woman’s real- self. Beth Henley has succeeded in providing a new realist vision of women’s abilities to face their inevitable tragic fates and how to conquer their despair. In Crimes of the Heart, the playwright uses certain method to present the development of the heroines’ characters through blending the tragic events with a comic frame. In fact, Henley focuses on the simple humorous activities more that the importance of the tragic event to present her vision of how to survive and face the crisis of life.

Crimes of the Heart is a play that is concerned about three sisters whose lives are headed in distinctly different directions; howe

... Show More
View Publication Preview PDF
Publication Date
Sun Feb 10 2019
Journal Name
Journal Of The College Of Education For Women
A Study of Person Deixis in J. M. Singe's Riders to the Sea
...Show More Authors

This study deals with an important area in the field of linguistics, namely person deixis.
The study aims at: (1) Describing the notion of deixis, its importance, and its place in the field
of linguistics, (2) Presenting a detailed illustration of person deixis, and (3) Conducting an
analysis of person deixis in one of Synge‟s plays Riders to The Sea according to Levinson‟s
model. The most important aim of these three is the third one (the analysis). To achieve this
aim, the researcher depends on Levinson‟s (1983) descriptive approach. According to the
descriptive approach of deixis, the category of person deixis can be defined as the encoding of
the participant roles in the speech situation. This encoding is r

... Show More
View Publication Preview PDF
Publication Date
Sat Dec 01 2012
Journal Name
Journal Of Economics And Administrative Sciences
The Concept of Fairness Accounting and its Role in Reducing Earnings Management Practices
...Show More Authors

The aims of research is diagnose and indicate the role of fairness in the work of accounting, which is important in reducing the unacceptable practices to manage earnings by economic units, As well as the interpretation and indicate Ethical inside in the accounting and accountants in particular practices in the area of ​​earnings management to reduce the negative effects of the practice and display the results mentioned acts according to what is supposed to be for the purposes of service users, Researchers have identified that one hypothesis, that "Fairness of accountants in of their work accounting lead to a reduction of earnings management practices". The results suggest that the accounting practices that lead to the manipu

... Show More
View Publication Preview PDF
Crossref
Publication Date
Fri Nov 24 2023
Journal Name
Iraqi Journal Of Science
Antibiogram of Escherichia coli Isolated from different Hospitals Wastewater in Erbil City, Iraq
...Show More Authors

Three hospitals were chosen for the present (Maternity hospital, Raperin hospital and Rhizgari hospital) survey within Erbil city, 36 water samples were collected at regular monthly interval periods beginning at January to December 2012. Microbial analysis was done by selective medium and biochemical tests and the isolated bacteria from those hospitals were Eshcerichia coli, Acinetobacter lowffii, Klebsiella pneumoniae, Moraxilla spp., Salmonella Typhi, Citrbtobacter freundii, Vibrio fluvials, Acinetobacter haemolyticus, Weeksella zoohelcum, Pasteurella multicida, and Pseudomonas aeroginosa. E. coli isolates were subjected to antimicrobial susceptibility testing. In vitro activities of 10 different antibiotics against E. coli isolates we

... Show More
View Publication Preview PDF
Publication Date
Wed Dec 30 2020
Journal Name
Iraqi Journal Of Science
Expansion Velocities of Elementary Gas in Comet Panstarrs Above 30000 Km from Nucleus
...Show More Authors

The coma gasses consist of molecules liberated from the nucleus by solar heating and relative sublimation. Once they have left the nucleus, these molecules in the coma are exposed to direct solar radiation and can be damaged in various ways due to the combined action of these reactions.

   One of some complex problems facing the research in this field is that the Maxwell-Boltzmann equation gives distribution function for one kind of particles which have same masses, but the gas has multi-groups of particles (Carbon, Neon, Sodium … etc.), where all these components must be in one program to extract average velocity of all and calculate particles velocity to each band. This problem is solved here by Matlab program a

... Show More
View Publication Preview PDF
Scopus (3)
Crossref (1)
Scopus Crossref
Publication Date
Thu Sep 26 2013
Journal Name
Astronomy & Astrophysics
High-resolution observations of SDSS J080800.99+483807.7 in the optical and radio domains
...Show More Authors

View Publication
Scopus (13)
Crossref (5)
Scopus Clarivate Crossref