Osteoarthritis (OA) is a disease of human joints, especially the knee joint, due to significant weight of the body. This disease leads to rupture and degeneration of parts of the cartilage in the knee joint, which causes severe pain. Diagnosis of this disease can be obtained through X-ray. Deep learning has become a popular solution to medical issues due to its fast progress in recent years. This research aims to design and build a classification system to minimize the burden on doctors and help radiologists to assess the severity of the pain, enable them to make an optimal diagnosis and describe the correct treatment. Deep learning-based approaches, such as Convolution Neural Networks (CNNs), have been used to detect knee OA using transfer learning with fine-tuning. This paper proposed three versions of pre-trained networks (VGG16, VGG19, and ResNet50) for handling the classification task. According to the classification results, The proposed model ResNet50 outperformed the other models a validation accuracy of 91.51% has been obtained.
