This study aimed to determine the effects of alcoholic and aqueous extracts of caper (Capparis Spinosa) and acetic acid on serum lipid profile and proteins levels in mice. Sixty adult mice with an average weight of 24±4 g grams were divided into four groups (15 mice for each). The first group (G1) was administrated daily with an oral dose of caper alcoholic extract (200 mg/kg) for 28 days. The second group (G2) was administrated daily with an oral dose of caper aqueous extract (200 mg/kg) for 28 days. The third group (G3) was administrated with a daily dose of 10 % acetic acid (2 ml/kg) for 28 days. The fourth Group (G4) was administrated daily with distilled water for 28 days, as a control group. The levels of lipid profile parameters, blood urea, total protein, albumin, and globulin were determined. The results showed a significant reduction (P≤0.05) in cholesterol and triglyceride levels in mice that were treated with alcohol or aqueous extracts of caper compared with acetic acid-treated and control groups. On the other hands, the results showed a significant reduction (P≤0.05) of blood urea levels in mice that were treated with alcohol or aqueous extracts of caper compared with acetic acid-treated and control groups. While the results recorded non-significant differences in the levels of total protein, albumin, and globulin in the serum of mice of different treatment groups. From the results, it can be concluded that caper has protective effects via acting to improve the lipid profile and urea level in the blood of mice.
This study was aimed to investigate the effects of Cuminum cyminum seed aqueous extract on the function and histological structure of rat kidney treated with dibutyl phthalate (DBP). Eighteen albino rats weighing 190-240g and aged 10-12 weeks were used for this study which went on for 28 days. The rats were divided into three groups (each with six animals): 1st group: control rats were given food and tap water, 2nd group was given DBP (420mg/Kg. B.W.) with tap water and diet, 3rd group were fed cumin plant orally at a daily dose of (200 mg/kg B.W.) and DBP (420mg/kg. B.W.) was given with drinking water and fed with diet daily. Kidney and liver function parameters were measured and hi
... Show MoreExposing the dorsal superficial skin of rats to partial-depth burn leads to bacterial and microbes Invasion. Topical treatment is required in most superficial burn cases Moist exposed burn ointment (MEBO) protects wounds from infection and enhances healing without any harmful effects of purified chemicals is caused. The topical using of HA gel in rat models with full and partial thickness surgical wounds shows enhancement in wound repair. In this study, we compared the healing efficacy of topical use of hyaluronic acid gel products with MEBO as standard management in rats that were exposed to a partial-thickness burn. The experiment included twenty-four (24) adult albino rats of male sex with weight (150-220 gm) of 3 months’ age divided i
... Show MoreIn this study, effects of shisha smoking on some blood components were evaluated in (120) male adult mice. The animals were divided into four groups according to smoke types (cigarette, shisha, cigarette +shisha) in addition to control groups which exposed to fresh air only. A special inhalation chamber designed locally has been used to expose the animals. Exposed to cigarette smoke was done for 5 min/day while exposed to shisha smoke for 15 min /day /7days/weeks for 4,8,12 weeks. Blood samples were collected to evaluate some hematological variables. The results showed that RBC, WBC count, Hb, PCV, differential leukocyte (Lymphocyte, Monocyte, Neutrphils) were significantly high (P≤0.001) in groups which exposed to shisha smoke as comp
... Show MoreThe present study was carried out to investigate the effect of oral administration of hot aqueous extract of beetle cocoon Larinus maculatus Faldermann, in a two doses 50 and100mg/Kg/Bw for 25 and 45days respect- tively on some organs such as liver, lung, kidney, intestine, heart, spleen, and brain in male mice Mus musculus. The results indicated that there were toxicopathological changes in many tissues of experimental animals. Histo -pathological changes was dose and period dependent . It was found that the aqueous extract of beetle cocoon has undesirable effect at the administered doses, since the raw extract of this cocoon is currently being used in Folk medicine as treatment for cough, bronchitis in Iraq. This study revealed that the l
... Show MoreSteps were taken to obtain the Kojic acid crystals from local fungal isolation A. flavus WJF81 by separating the fermentation products from the fungus mycelium from the production plant at the centrifuge at a speed of 5000 cycles for 10 minutes. The extraction was followed by ethyl acetate then supernatant concentrate by using rotary evaporator, and dried with heat oven 37ºC. Long, yellowish, pristine acid crystals were obtained that examined the optical microscope with a magnification force of 10x and 40x. The melting point of kojic acid was determined between 152.9-153.5 °C Results of the diagnosis of Kojic acid by applying High pressure liquid chromatography HPLC technique showed that the acid was at one peak, which was close to the
... Show MoreTraditional folk medicine is applied in the treatment of diversity chronic and acute conditions all over the worlds. This study was carried out to assess the capability of aqueous beetle cocoon extract (Lorinus maculates F.) commonly known as (Tihan) in stimulating immune response. Adult mice (5 in each group) were divided into two groups: the first one orally administered with 150 mg/kg and the second group received normal saline as a control group for 14 days. Bone marrow and spleen were proceed for mitotic index and phagocytosis estimated. The results showed a significant increase in mitotic index and phagocytosis in treaded mice in comparing with the negative control. These results concluded that Tihan has a
... Show MoreBackground: Diabetic retinopathy is an important complication of diabetes mellitus. It is supposed that elevated sialic acid in diabetes mellitus plays an important role in diabetic retinopathy. This study investigated serum total sialic acid levels related to glycemic control, blood pressure, retinopathy, and serum lipid level in diabetic retinopathy patients.
Patients & Methods: Type 2 diabetic patients aged (56.47±10.68) years were recruited for the study. Fasting venous blood samples were collected from 132 diabetic subjects of whom 79 without retinopathy and 53 were diabetic with retinopathy. All the blood samples were processed for serum total sialic acid (TSA), fasting serum glucose (FSG), HbA
The quantitative determination of the estrogen E2, Progestron P4 & follicle stimulating hormones FSH in the serums of Albino mice used in the experiments & treated by crude alcoholic extracted 95% of the seeds & leaves of Apium graveolens was a significant increase in the concentration of estrogen of different kinds of the extracted in comparison with the values of the coefficient of the control group, that is the study recorded a significant increase of the concentration of estrogen; it was the highest in the mice which was administrated by the methanolic extracted 95%, then it was less in the mouse which was administrated by the ethanolic extracted., and it was the least in the mice which were administrated by the crude ethanolic-methano
... Show MoreThe amount of protein in the serum depends on the balance between the rate of its synthesis, and that of its catabolism or loss. Abnormal metabolism may result from nutritional deficiency, enzyme deficiency, abnormal secretion of hormones, or the actions of drugs and toxins. Renal cancer is the third most common malignancy of the genitourinary system, and accounts for 3% of adult malignancies globally. Total serum proteins were measured in malignant kidney tumor, benign kidney tumors, and non tumoral kidney diseases patient groups, as well as in healthy individuals. A significant decrease (p< 0.001) of total serum protein levels in patients with malignant kidney tumors when compared with those of benign tumors, non tumoral diseases, and hea
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