This study was performed to assess the correlation of serum interleukins (ILs) levels with anthropometric data and lipid profile status in blood samples obtained from 100 Iraqi obese women with polycystic ovary syndrome PCOS. Obese non PCOS healthy women (n=75) matching in age (19-38 years) and body mass index(29.9-33.4kg/m2) served as a control group. The samples were collected from Kamal Al-Samurai Teaching hospital during the period of December 2017- June 2018.ELISA kits were used to measure serum levels of IL-6,IL-10,IL-18, IL-29,IL-33,tumor necrotic factor (TNF-α),high sensitive C-reactive protein (hsCRP), insulin, total testosterone, and sex hormone binding globulin(SHBG).The biochemical measurements of blood glucose and lipid profile were performed by conventional colorimetricmethods. The results demonstrated significant differences(P < 0.01) in serum levels of all interleukins and lipid profile parameters in obese PCOS in comparison with obesenon PCOS control women.In addition, PCOS women had higher insulin and FAI levels in comparison to non PCOS women. The findings suggest that androgen excess, indicated by high free androgen index (FAI),might serve as an indicator of a prediabetic status, as it might promote insulin resistance and ð›½-cell dysfunction in PCOS women. Circulatory interleukin levels in obese PCOS women may act on the development of insulin resistance and androgen oversupply in PCOS,suggesting that high serum ILs levels were related to insulin resistance (IR) and androgen excess but not to body mass index. A high IL level is not an elemental characteristic of PCOS, but it may act in promoting IR and hyperandrogenism of PCOS.
Background: Diabetes mellitus is a major health issue that is one of the leading causes of cardiovascular disease. Recent studies have found a link between uncontrolled diabetes and cardiovascular disease, with dyslipidaemia predicting glycated-hemoglobin (HbA1c), which could be a major contributor to type 2 diabetes complications and etiology.
Objectives: The objective of present study was estimate lipid profiles among control and uncontrolled type 2 diabetic patients.
Subjects and Methods: Analytical case control based study, One hundred twenty participate were included in study, 70 patients with DM as case group refer to Abuagala Center and difference follow up diabetic center and 50 non diabetic subjects taken as
... Show MoreBack ground: Chronic hepatitis C (HCV) is the most common chronic liver disease at present, and HCV infection is found with variable prevalence in dialysis populations in different parts of the world.
Objective: The aim of this study was to determine the concentration of sialic acid and immunoglobulins level in the sera of patients with chronic renal failure whom infected with Hepatitis C virus, and the effect of hemodialysis on them.
Patients&Methods: Regarding to this aim, total sialic acid levels (TSA) and immunoglobulins level were studied on the blood samples of 20 patients with chronic renal failure + Hepatitis C virus (positive group) and 20 patients with chronic renal failure (negative group) and 20 healthy volunteers.
Background: Prostaglandin D2 (PGD2) is a lipid mediator appeared as a powerful activator that regulates the T-helper2 (TH2) and Type-2 innate lymphoid cells (ILC2), and functions as diagnostic marker and it has probable therapeutic targets for asthma.
Objectives: To define the role of Prostaglandin D2 biomarkers in disease severity, and to forecast disease risk and progression.
Patients and methods: A case control study was conducted on Forty four Iraqi asthmatic patients and 44 apparently healthy controls who were age and sex matched. Four ml of blood samples was taken from the study groups for the detection PGD2 using ELISA.
Results: The se
... Show MoreBackground: Chronic leg ischemia commonly affects the arteries supplying the leg and mostly caused by atherosclerosis. Triplex ultrasound scanning is useful for delineating the anatomic site of disease in the lower limb in addition to the grading of the stenosis and evaluation of post-stenotic flow.
Objectives: To determine the extent of vasculopathy in patients with chronic leg ischemia by using triplex ultrasound scanning and match the sonographic findings with the clinical signs and symptoms.
Patients and methods: A cross sectional study from October 2009 to September 2010 was performed on 56 patients with clinical suspicion of chronic leg ischemia referring to ultraso
... Show MoreAbstract Depending on their protective properties against different cases of Colorectal Cancer (CRC), vitamins C, D, and E are the main focus of this research. CRC is one of the global public health concerns. 30 healthy individuals provided serum samples, whereas the group of CRC patients was divided into three, totaling 90 individuals. Group I consisted of 30 newly diagnosed cases of CRC. Group II 30 consisted of consisted of 30 CRC patients who were administered three cycles of chemotherapy. Group III consisted of 30 diagnosed CRC patients who also have non-alcoholic fatty liver disease (NAFLD). The concentrations and groups of vitamins C, D, and E were evaluated using ELISA. The levels of Vitamin C were significantly lower (p &l
... Show MoreOtitis media with effusion (OME) is a common disease especially among young children (before school age) and it is one of the common causes of acquired hearing loss in childhood. Pediatric patients with OME are usually undernourished. The purpose of this study is to determine whether the serum levels of trace elements (zinc, copper, magnesium, iron) have a role in the development of OME in children. This study carried out on 55 children and subdivided them into two groups. Group 1 (patient group) consist of 30 children suffering from OME and group 2 (control group) included 25 apparently healthy children. Serum levels of zinc, copper, magnesium and iron were measured for both groups. Comparison the results between the two groups showed t
... Show MoreHealth literacy is an important method used by the authorities to strengthen the health system. The aim of this study is to assess the knowledge of some basic health principles among women of different educational states. This is a crosssectional study, performed from December 2014 until January 2016, Baghdad. All candidates were: females > 18 years, neither medical staff nor students. They were divided into two groups: educated and uneducated. The sample included 213 women, there were 112 educated and 101 uneducated women. Regarding educated group, accurate answers regarding route of transmission of typhoid fever was 73.2% in educated subjects vs. 49.5% in uneducated subjects. Main source of information for both groups was p
... Show MoreThis study aimed to determine the effects of alcoholic and aqueous extracts of caper (Capparis Spinosa) and acetic acid on serum lipid profile and proteins levels in mice. Sixty adult mice with an average weight of 24±4 g grams were divided into four groups (15 mice for each). The first group (G1) was administrated daily with an oral dose of caper alcoholic extract (200 mg/kg) for 28 days. The second group (G2) was administrated daily with an oral dose of caper aqueous extract (200 mg/kg) for 28 days. The third group (G3) was administrated with a daily dose of 10 % acetic acid (2 ml/kg) for 28 days. The fourth Group (G4) was administrated daily with distilled water for 28 days, as a control
... Show MoreBackground: Anemia is very common in patients with chronic kidney disease, and becoming almost universal in end stage renal disease, where dialysis or renal transplantation becoming the treatment of choice. High levels of hepcidin appear to accompany reduced renal function and serum ferritin may also be elevated.
Objectives: To classify anemia in hemodialysis patients and to display the correlations between the types of anemia and inflammatory parameters like hepcidin and ferritin according to vascular access of hemodialysis.
Patients and methods: This case-control study was conducted at Al-Hayat center for hemodialysis, and included 60 adult patients on hemodialysis. Also 20 healthy individuals were recruited as control group. Mea
Background: Studies discussing the correlation between biochemical markers of bone turnover and the diagnosis of osteoporosis in postmenopausal Iraqi women are rare. This study is devoted to find out the significance of serum osteocalcin (OC) and osteopontin (OPN) levels with the incidence of osteoporosis and its major complication (fracture).Objectives: to investigate the significance of bone turnover biochemical markers; serum osteocalcin and serum osteopontin in evaluating osteoporosis for postmenopausal Iraqi women with and without history of vertebral fracture, as well as to explore the relationship of these markers with bone mineral density (BMD).Methods: Fifty seven postmenopausal women whose ages are fifty years old and over, cat
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