Dysregulation of matrix metalloproteinases-9 (MMP-9) and tissue inhibitors of
matrix metalloproteinases-1 (TIMP-1) may contribute to the development of
cardiovascular diseases in type 2 diabetes mellitus (T2DM) patients. The aim of this
study was to determine the effects of chronic hyperglycemia on serum
concentrations of MMP-9 and TIMP-1of T2DM patients without dyslipidemia (one
of atherosclerosis risk factors) and with duration less than 5 years in comparison
with T2DM patients with dyslipidemia and with duration more than 10 years and
controls. Also to investigate if serum levels of MMP-9 and TIMP-1 could be
potential markers for early detection of the development of cardiovascular
complications in T2DM patients without dyslipidemia. This study consisted of 24
T2DM patients without dyslipidemia, 30 T2DM patients with dyslipidemia, and 26
healthy subjects. A variety of inflammatory markers including: MMP-9, TIMP-1,
IL18 and hs-CRP were compared among the three groups. The BMI was similar
among the three groups. A significant increase of WHR, WHtR, FPG, TC, TG,
LDL-C, VLDL-C, AIP, atherogenic ratio-1, atherogenic ratio-2, hs-CRP, MMP-9,
TIMP-1 and IL-18 with a significant decrease of HDL-C, β Cell% and S% among
the three groups. MMP-9 of T2DM patients without dyslipidemia and with duration
less than 5 years showed a significant positive correlation with FPG and a
significant negative correlation with TC. MMP-9 of T2DM patients with
dyslipidemia and with duration more than 10 years showed significant negative
correlation with LDL-C. TIMP-1 of T2DM patients with dyslipidemia and with
duration more than 10 years showed a significant negative correlation with TC, TG,
VLDL-C and atherogenic ratio-1. The significant increased levels of both MMP-9
and TIMP-1 in T2DM patients without dyslipidemia and with duration less than 5
years compared to controls showed that those patients have risk factor for
cardiovascular complications. This study suggests that MMP-9 and TIMP-1 may be
potentially useful as markers in T2DM patients at risk of progression of
cardiovascular diseases.
A new class of thiadiazole /silica nanocomposites with chemical bonds between thiadiazole monomers and modified nanosilica surface were synthesized by free radical polymerization. Presence silica nanoparticles in the structure of nanocomposite showed effectively improve the physical and chemical properties of Producing polymers. A nanocomposite material with feature properties comparison with their polymers, The structure and morphology of the synthesis materials were investigated by FT-IR spectrum which display preparation new thiadiazole compounds and polymerization monomers. FT-IR showed disappeared double bond (C=C) of monomers, due to produce long chains of thiadiazole polymers and nanocomposite. X-ray diffraction gave idea ab
... Show MoreThe study aims to identify the level of cognitive beliefs, as well as to identify the level of self-organized learning strategies among intermediate school students. The study also aims to identify the differences in the level of self-organized learning strategies among intermediate school students in term of gender, branch (scientific, literary). In order to achieve the research objectives, the researcher designed a scale to measure the cognitive beliefs. As for the scale of self-organized learning strategies, the researcher adopted a scale of (Pintrich et al. 1991), which was translated by (Izzat Abdelhamid, 1999) , For self-organized learning strategies, the sample consisted of (400) students from the research population, whic
... Show MoreThe most important topic for psychologist generally is factor of education and it's active tools because learning needs active perception for stimulus that recived by the educator and give it avalue and meaning , Need for cognition is
very important in the various daily fields of life , especially in learning and teaching and the academy work , it help with shifting the learning level for people , and icreas the intense and challenge between them
The research endeavored to achieve the following aim :
1- Measuring the level of peripheral perception for the university student .
2- Measuring the level of need for cognition for the university student .
3- Measuring the level of peripheral perception for the university student
The availability of low- cost adsorbent namely Al-Khriet ( a substance found in the legs of Typha Domingensis) as an agricultural waste material, for the removal of lead and cadmium from aqueous solution was investigated. In the batch tests experimental parameters were studied, including adsorbent dosage between (0.2-1) g, initial metal ions concentration between (50-200) ppm (single and binary) and contact time (1/2-6) h. The removal percentage of each ion onto Al-Khriet reached equilibrium in about 4 hours. The highest adsorption capacity was for lead (96%) while for cadmium it was (90%) with 50 ppm ions concentration, 1 g dosage of adsorbent and pH 5.5. Adsorption capacity in the binary mixture were reduce at about 8% for lead a
... Show MoreAnalysis the economic and financial phenomena and other requires to build the appropriate model, which represents the causal relations between factors. The operation building of the model depends on Imaging conditions and factors surrounding an in mathematical formula and the Researchers target to build that formula appropriately. Classical linear regression models are an important statistical tool, but used in a limited way, where is assumed that the relationship between the variables illustrations and response variables identifiable. To expand the representation of relationships between variables that represent the phenomenon under discussion we used Varying Coefficient Models
... Show MoreLet be an n-Banach space, M be a nonempty closed convex subset of , and S:M→M be a mapping that belongs to the class mapping. The purpose of this paper is to study the stability and data dependence results of a Mann iteration scheme on n-Banach space
Data security is a significant requirement in our time. As a result of the rapid development of unsecured computer networks, the personal data should be protected from unauthorized persons and as a result of exposure AES algorithm is subjected to theoretical attacks such as linear attacks, differential attacks, and practical attacks such as brute force attack these types of attacks are mainly directed at the S-BOX and since the S-BOX table in the algorithm is static and no dynamic so this is a major weakness for the S-BOX table, the algorithm should be improved to be impervious to future dialects that attempt to analyse and break the algorithm in order to remove these weakness points, Will be generated dynamic substitution box (S-B
... Show MoreOffline Arabic handwritten recognition lies in a major field of challenge due to the changing styles of writing from one individual to another. It is difficult to recognize the Arabic handwritten because of the same appearance of the different characters. In this paper a proposed method for Offline Arabic handwritten recognition. The proposed method for recognition hand-written Arabic word without segmentation to sub letters based on feature extraction scale invariant feature transform (SIFT) and support vector machines (SVMs) to enhance the recognition accuracy. The proposed method experimented using (AHDB) database. The experiment result show (99.08) recognition rate.
A proposed feature extraction algorithm for handwriting Arabic words. The proposed method uses a 4 levels discrete wavelet transform (DWT) on binary image. sliding window on wavelet space and computes the stander derivation for each window. The extracted features were classified with multiple Support Vector Machine (SVM) classifiers. The proposed method simulated with a proposed data set from different writers. The experimental results of the simulation show 94.44% recognition rate.
Objective: We hypothesized that attacking cancer cells by combining various modes of action can hinder them from taking the chance to evolve resistance to treatment. Incorporation of photodynamic therapy (PDT) with oncolytic virotherapy might be a promising dual approach to cancer treatment. Methods: NDV AMHA1 strain as virotherapy in integration with aminolaevulinic acid (ALA) using low power He-Ne laser as PDT in the existing work was examined against breast cancer cells derived from Iraqi cancer patients named (AMJ13). This combination was evaluated using Chou–Talalay analysis. Results: The results showed an increased killing rate when using both 0.01 and 0.1 Multiplicity of infection (MOI) of the virus when combined with a dose of 617
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