
In this study miconazole nitrate was formulated as topically applied emulgel; different formulas were prepared using sodium carboxymethylcellulose (SCMC) and carboxypolymethylene (carbomer 941) as gelling agents. The influence of type of gelling agent and concentration of both oil phase and emulsifying agent on drug release was studied and compared with commercially available miconazole nitrate cream (Mecozalen®). The results of in vitro release showed that SCMC emulgel bases gave better release than carbomer 941 bases and the release of drug increase from both bases as a function of increasing the concentration of emulisifying agent. The oil phase had retardation effect when
... Show MoreThis study was aimed to one of the most prevalent causes for endodontic treatment failure is the presence of Enterococcus faecalis bacterium within teeth root canals. To achieve successful treatment, it is so important to study E. faecalis behavior. The aim of study was to investigate biofilm production and antibiotic sensitivity of E. faecalis isolated from root canals. Results showed isolation of E. feacalis (65%) of samples, identified by specific gene by PCR technique. Most isolates were sensitive to Imipenem and resistant to Erythromycin, Clindamycin, Tetracycline and Trimethoprim. Strong biofilm production was detected among 29.5% of highest antibiotic resistant isolates. The results may indicate that infected root canals with E. feac
... Show MoreRefractories are mineral and chemical-, based, materials with excellent heat resistance, making them ideal for use in the construction of ovens, furnace walls industries. According to this our research is concerned to study the effect of addition of (4% CaO) and (5% graphite) on the silica brick properties. Different amounts of CaO and Graphite were included in the white sand (raw ingredients) of silica bricks as a binder to prepare the composition then the composition were sintered using Different sintering temperatures ranging from (1000–1400)𝛐C under static air. Density, thermal conductivity, porosity, and water absorption Compression there was power tested after sintering. XRD analysis was used to identify raw materials’
... Show MoreNew derivatives of the anti-inflammatory, leprostatic drug dapsone 4 are synthesized, characterized and biologically screened by the treating the drug dapsone with chloroacetyl chloride in the presence of base. Both amino groups are acylated to give compound 6. The symmetrical acylated product then treated with Phenol, N-Acetyl-p-aminophenol, p-Chlorophenol, m-Chlorophenol, o-Hydroxybezoic acid and m-Hydroxybezoic acid to give compounds 8(a-f). The antimicrobial activity was tested for the synthesized compounds; activates were good compared to the parent drug. All the new compounds have scanned for their biological activities toward gram ‒ve and gram +ve (M. tuberculosis, S. pneumoniae, E. coli and P. mirabilis) bacteria, the synthesized
... Show MoreA stylistic study in the poetry of Hafiz Ibrahim, praise be to God, Lord of the worlds, and prayers and peace be upon his best messengers, and the seal of his prophets, Muhammad and his good and pure family, and after ...
The poet Hafez Ibrahim is considered one of the well-known poets in the modern era, and his language was distinguished by sobriety, eloquence in expressions, and beautiful meanings And he had my journey in the study of his poetry a stylistic study, and the research came with an introduction in which the concept of stylistics was briefly explained, since it was studied by many researchers, then divided the research into three topics: I studied in the first the construction of the poem, and I stood at the most importan
Morinda citrifolia fruit have been used treatment numerous diseases such as dysentery, heart diseases, AIDS, cancers and others. The aim of this study was to determine the antibacterial and antioxidant activities of anthraquinones fractions from the fruits of Morinda citrifolia. Well diffusion assay, minimum inhibitory concentration and the minimum bactericidal concentration were used to test antibacterial activity against Staphylococcus aureus, Escherichia coli, Bacillus cereus, Pseudomonas aeruginosa MRSA and Helicobacter pylori. DPPH radical scavenging activity and Superoxide dismutase activity assays were used to evaluate their antioxidant activity. LC-MS analysis was used to identify anthraquinones and SEM studies that revealed mode of
... Show MoreThe purpose of the study was to isolate the anthraquinone fractions from the fruit, leaves and roots of Morinda citrifolia. Anthraquinones extracts from the fruit, leaves and roots of M. citrifolia exhibited six red bands for the fruit, five for the leaves and four for the roots under UV light at wavelength 245 nm and 356 nm exhibited strong absorption bands at 3408.83, 3275.52 and 3308.88 cm-1 for anthraquinone extract from the fruit, leaves and roots of M. citrifolia respectively identified by O-H stretching. C-H stretching groups were detected at the bands 2954.74 and 2857.38 cm-1 (fruit), 2928.13 cm-1 (leaf), 2922.31cm-1 and 2852.95 cm-1 (root). The C=O group of M. citrifolia fruit were detected at the band 1726.27 cm-1, leaves at 1600.
... Show MoreClerodendron inerme is used to treat asthma, inflammation, Parkinson’s diseases, and other diseases.This research is aimed to determine antibacterial and antioxidant effects in the anthraquinones’ fraction of Clerodendron inerme leaves.Well-diffusion agar, minimum inhibitory concentration, and minimal bactericidal concentration were used to test the antibacterial properties of the four types of bacteria.DPPH radical scavenging assay was used to evaluate their antioxidant activity.GC-MS and FTIR analysis were used to identify anthraquinones compounds of the leaves in the plant.Anthraquinones component from the leaves of C.inerme has shown significant inhibition against pathogenic bacteria, including Pseudomonas aeruginosa. The an
... Show MoreThis study was aimed to evaluate atotal phenolic content, antibacterial activity, and antioxidant activity of M. communis callus extracts were evaluated. Callus induction in general Murashige and Skoog (MS) media is completed by the Benzil adenine's unique knowledge of callus formation. A well diffusion experiment was used to examine antibacterial interest in Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia, and Pseudomonas aeruginosa. The DPPH radical scavenging activity test was used to measure antioxidant activity. FTIR and HPLC have been used to pinpoint the presence of polyphenol compounds in calluses. The total phenol content of plant leaves extract (0.1, 0.5, and 1) mg/ml was 42.12, 94.08, and 189 mg of Gallic ac
... Show MoreSixty four local isolated of Klebsiella spp. have been isolated from environment samples (soil and water). These isolates were identified and diagnosis according to phenotype and biochemical tests. These isolates were subjected to primary and secondary screening, to select the isolate with the highest laccase activity. Fifteen isolates chosen from primary screening for screening their enzyme activity in secondary screening. It has been found the Klebsiella(K7) has the highest productivity of the enzyme (12 Unit/ml).Klebsiella(K7) isolate was diagnosis by Vitak 2 system, it was identified asK. pneumonia. The laccase purified was characterization, the experiments showed that: The molecular weight of laccase was 120KD and the optimum pH for th
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