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Designing of Human Serum Albumin Nanoparticles for Drug Delivery: a Potential Use of Anticancer Treatment
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Human serum albumin (HSA) nanoparticles have been widely used as versatile drug delivery systems for improving the efficiency and pharmaceutical properties of drugs. The present study aimed to design HSA nanoparticle encapsulated with the hydrophobic anticancer pyridine derivative (2-((2-([1,1'-biphenyl]-4-yl)imidazo[1,2-a]pyrimidin-3-yl)methylene)hydrazine-1-carbothioamide (BIPHC)). The synthesis of HSA-BIPHC nanoparticles was achieved using a desolvation process. Atomic force microscopy (AFM) analysis showed the average size of HSA-BIPHC nanoparticles was 80.21 nm. The percentages of entrapment efficacy, loading capacity and production yield were 98.11%, 9.77% and 91.29%, respectively. An In vitro release study revealed that HSA-BIPHC nanoparticles displayed fast dissolution at pH 7.4 compared to pH 3.4. They have also showed a higher cytotoxic activity against MCF-7 human breast cancer cells. The possible binding of the BIPHC into the tyrosine threonine kinase (TTK) was studied using molecular modeling. The findings of this study introduced a promising candidate model of HSA nanoparticles for delivering of BIPHC anticancer drug. These novel nanoparticles are characterized by their ability to carry a hydrophobic BIPHC agent and control drug release with improved targeting of breast cancer cells.

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Publication Date
Thu Dec 29 2016
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Proposal for Exchange Text message Based on Image
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     The messages are ancient method to exchange information between peoples. It had many ways to send it with some security.

    Encryption and steganography was oldest ways to message security, but there are still many problems in key generation, key distribution, suitable cover image and others. In this paper we present proposed algorithm to exchange security message without any encryption, or image as cover to hidden. Our proposed algorithm depends on two copies of the same collection images set (CIS), one in sender side and other in receiver side which always exchange message between them.

      To send any message text the sender converts message to ASCII c

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Publication Date
Sun Apr 30 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Fast Training Algorithms for Feed Forward Neural Networks
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 The aim of this paper, is to discuss several high performance training algorithms fall into two main categories. The first category uses heuristic techniques, which were developed from an analysis of the performance of the standard gradient descent algorithm. The second category of fast algorithms uses standard numerical optimization techniques such as: quasi-Newton . Other aim is to solve the drawbacks related with these training algorithms and propose an efficient training algorithm for FFNN

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Publication Date
Mon Oct 30 2023
Journal Name
Iraqi Journal Of Science
Review on Hybrid Swarm Algorithms for Feature Selection
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    Feature selection represents one of the critical processes in machine learning (ML). The fundamental aim of the problem of feature selection is to maintain performance accuracy while reducing the dimension of feature selection. Different approaches were created for classifying the datasets. In a range of optimization problems, swarming techniques produced better outcomes. At the same time, hybrid algorithms have gotten a lot of attention recently when it comes to solving optimization problems. As a result, this study provides a thorough assessment of the literature on feature selection problems using hybrid swarm algorithms that have been developed over time (2018-2021). Lastly, when compared with current feature selection procedu

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Publication Date
Tue Mar 30 2021
Journal Name
Iraqi Journal Of Science
Weighted k-Nearest Neighbour for Image Spam Classification
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E-mail is an efficient and reliable data exchange service. Spams are undesired e-mail messages which are randomly sent in bulk usually for commercial aims. Obfuscated image spamming is one of the new tricks to bypass text-based and Optical Character Recognition (OCR)-based spam filters. Image spam detection based on image visual features has the advantage of efficiency in terms of reducing the computational cost and improving the performance. In this paper, an image spam detection schema is presented. Suitable image processing techniques were used to capture the image features that can differentiate spam images from non-spam ones. Weighted k-nearest neighbor, which is a simple, yet powerful, machine learning algorithm, was used as a clas

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Publication Date
Thu Jan 20 2022
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Birefringence for Elliptical-Core Fibers with Low Ellipticities
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Model birefringence was measured for elliptical-core fibers with low ellipticities, note the birefringence depends strongly on the frequency, especially when fiber is being operated near the higher mode cutoff where ν  for circular fiber of the single-mode type that correspond to the birefringence maximum. When ν  this also correspond to the birefringence maximum that can be introduced in an elliptical core fiber while still operating in the single-mode regime near the higher mode cutoff. Also the birefringence is proportional to the fiber core ellipticity when core ellipticity is much less than unity, but this birefringence deviates from the linear for the large core ellipticities.

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Publication Date
Wed Dec 30 2015
Journal Name
College Of Islamic Sciences
Phonological features   For spoken text in the language
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This research attempted to take advantage of modern techniques in the study of the superstructural phonetic features of spoken text in language using phonetic programs to achieve more accurate and objective results, far from being limited to self-perception and personal judgment, which varies from person to person.
    It should be noted that these phonological features (Nabr, waqf, toning) are performance controls that determine the fate of the meaning of the word or sentence, but in the modern era has received little attention and attention, and that little attention to some of them came to study issues related to the composition or style Therefore, we recommend that more attention should be given to the study of

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Publication Date
Fri Dec 31 2021
Journal Name
Journal Of Legal Sciences
International responsibility for damage caused by cyber attacks
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The research sheds light on a new topic of international law, the most important of which is, around which there are still question marks and differences in most of its aspects, especially with regard to international liability for damage caused by cyber attacks in the virtual space, the last is the fifth area that appeared alongside other area (Land, sea, air and outer space) and in addition to being a space on which states depend in the performance of their functions and international relations, it is a new arena for war and a source of danger to the security of states, As the security exposure to the secrets of states increased due to espionage and piracy, and the attacks on the infrastructure of countries increased, and the silence o

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Publication Date
Wed Jan 02 2019
Journal Name
Journal Of Educational And Psychological Researches
Parents Role in Social Personality Formation for Children
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Experts of Psychology and education emphasized that childhood is one of the most important stages in the formation of human personality, and the most influential in his public life, especially the stage in which he lives within his family, which must provide him with the requirements of healthy growth of physical, emotional, moral and social. Emotional-social connection of the child to his family, is especially important in determining the characteristics of his social character, in accordance with the norms and values ​​prevailing in society. This requires the child to be cared for and cared for, and to deal with him in a healthy social manner. So as to achieve positive growth and harmony in the process of social control in internal

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Publication Date
Tue Mar 31 2015
Journal Name
Al-khwarizmi Engineering Journal
Profiles and Geotechnical Properties for some Basra Soils
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 Abstract

Basra province is known for its logistic location for trading activity and oil industry. By geological point of view, Basra areas are believed to consist mainly of alternation of (clay, silty clay, clayey silt, silt and sand) type of soil. Any development of industry in this area should be affected by the occurrence of the clay soil. That is why the investigation to the soil is more than necessary. In this case, a vast testing program was carried out by the author to evaluate the various formations constituting the of some Basra soils. An attempt to characterize and discuss the nature, minerals, engineering behavior and field properties of soil samples extracted from more than one thousand and one

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Publication Date
Thu May 25 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Modulation Function Calculation For Optical Semiconductor Fractal Modulator
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   The research  includes the study and calculation of the modulation function of Optical Semiconductor Fractal  Modulator and spatial frequency for different values of Silicon modulator transmittance percentage(10%,35%,45%,58%),it found the relation between the modulation function of Silicon and spatial frequency, the exponential relation of all values of the transmittance , the best state of modulation function when the value of transmittance is T=58% ,also the research includes the study of the relation of transmittance with different values of refractive index of Silicon . So the research involves building a computer program of output data which would relate to fractal optical modulation made of semiconductor mate

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