Enhancing the therapeutic potential of curcumin: a novel nanoformulation for targeted anticancer therapy to colorectal cancer with reduced miR20a and miR21 expression
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(3)
Publication Date
Thu Feb 16 2023
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
A Novel Single Nucleotide Polymorphism of Interleukin-10 Gene is Linked to Type 2 Diabetes Mellitus in Iraqi Patients with Toxoplasmosis(Conference Paper )#
Interleukin 10
type 2 diabetes mellitus
IL10 gene polymorphism
Toxoplasma gondii
Type 2 diabetes mellitus (T2DM) is a chronic disorder that is a serious health concern all over the globe, it is linked to Interleukin-10 (IL-10) single nucleotide polymorphisms (SNPs) at the promoter region. On the other hand, diabetes influences the cellular and humoral immunity predisposing the patient to a variety of opportunistic parasites one of them is Toxoplasma gondii (T. gondii), which may infect any nucleated cell, including pancreatic cells. The purpose of this research was to explore the association of IL-10 genetic polymorphisms with T2DM and latent toxoplasmosis among Iraqi patients with T2DM. Fifty-five and fifty-eight venous blood samples were taken from T2DM patients and age-matched non-diabetic person
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Publication Date
Sat Sep 01 2018
Journal Name
King's College London
A novel sol-gel silica formulation for management of methadone hydrochloride abuse
Introduction: Methadone hydrochloride (MDN) is an effective pharmacological substitution treatment for opioids dependence, adopted in different countries as methadone maintenance treatment (MMT) programmes. However, MDN can exacerbate the addiction problem if it is abused and injected intravenously, and the frequent visits to the MMT centres can reduce patient compliance. The overall aim of this study is to develop a novel extended-release capsule of MDN using the sol-gel silica (SGS) technique that has the potential to counteract medication-tampering techniques and associated health risks and reduce the frequent visits to MMT centres. Methods: For MDN recrystallisation, a closed container method (CCM) and hot-stage method (HSM) were conduc
... Show MorePublication Date
Mon Jun 09 2025
Journal Name
Journal Of Discrete Mathematical Sciences And Cryptography
A novel improvement of skew tent map for generating Pseudo random numbers
An encryption system needs unpredictability and randomness property to maintain information security during transmission and storage. Although chaotic maps have this property, they have limitations such as low Lyapunov exponents, low sensitivity and limited chaotic regions. The paper presents a new improved skewed tent map to address these problems. The improved skew tent map (ISTM) increases the sensitivity to initial conditions and control parameters. It has uniform distribution of output sequences. The programs for ISTM chaotic behavior were implemented in MATLAB R2023b. The novel ISTM produces a binary sequence, with high degree of complexity and good randomness properties. The performance of the ISTM generator shows effective s
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Publication Date
Thu Feb 16 2017
Journal Name
Signal, Image And Video Processing
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Publication Date
Mon Nov 25 2019
Journal Name
Alustath Journal For Human And Social Sciences
Barbara Kingsolver: Evaluating Her Contribution to the Eco-Feminist Novel
Climate change, together with terrorism, economic depressions, and mass-destructive weaponry, is a source of international phobia for many people. The advancement in technology increases the competition among world powers and economic systems to develop their industrial enterprises. The smoke that emits from the factories, the pollution caused by the industrial projects, the excessive use of green gas result in the increase of global warming and have catastrophic effects on the ecosphere of the planet. Besides, man’s wrong practices even in agricultural matters are exhausting the natural resources of the lands, and they badly affect the ecological diversity and the wellbeing of the humans and non-humans alike. Contemporary feminis
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(1)
Publication Date
Tue Dec 05 2023
Journal Name
Baghdad Science Journal
A Novel System for Confidential Medical Data Storage Using Chaskey Encryption and Blockchain Technology
Blockchain
BFlow
Chaskey
Healthcare
IoT
Security
Secure storage of confidential medical information is critical to healthcare organizations seeking to protect patient's privacy and comply with regulatory requirements. This paper presents a new scheme for secure storage of medical data using Chaskey cryptography and blockchain technology. The system uses Chaskey encryption to ensure integrity and confidentiality of medical data, blockchain technology to provide a scalable and decentralized storage solution. The system also uses Bflow segmentation and vertical segmentation technologies to enhance scalability and manage the stored data. In addition, the system uses smart contracts to enforce access control policies and other security measures. The description of the system detailing and p
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Publication Date
Wed Jul 01 2020
Journal Name
International Journal Of Drug Delivery Technology
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Publication Date
Fri May 24 2013
Journal Name
American Journal Of Pharmacological Sciences
Publication Date
Fri Jul 29 2022
Journal Name
Journal For Vascular Ultrasound
A Comparative Study of the Right and Left Carotid Arteries in Relation to Age for Patients With Diabetes and Hypertension
Introduction:
Introduction: Age
hypertension
and diabetes can cause significant alterations in arterial structure and function
including
changes in lumen diameter (LD)
intimal-medial thickness (IMT)
flow velocities
and arterial compliance. These are also considered
risk markers of atherosclerosis and cerebrovascular disease. A difference between right and left carotid artery blood flow and
IMT has been reported by some researchers
and a difference in the incidence of nonlacunar stroke has been reported between
the right and left brain hemispheres. The aim of this study was to determine whether there are differences between the right and
left common carotid arteries and internal carotid arteries in patients with hypertension and diabetes for 2 age groups.
Methods: We studied 250 patients with both diabetes and hypertension. Patients were divided into 2 age groups with the
old age group being 56 to 75 years and the young age group 35 to 55 years. The bilateral common carotid and internal carotid
arteries were evaluated with B-mode ultrasound and Doppler examinations. The LD and IMT were measured for both common
carotid arteries
and spectral waveform parameters and indices were recorded for both internal carotid arteries.
Results: The difference in LD between the left and right common carotid arteries for the old age group was 11.64% and for the
young age group was 6.42%
with significant P values of <.05 for both age groups. The difference in IMT between the left and
right common carotid arteries was 18.27% in the old age group compared with 15.38% in the young age group
with significant
P values of <.05. There was a difference in peak systolic velocity between the left and right internal carotid arteries of 4.85%
in the old age group which was not significant
compared with 14.28% in the young age group with a significant P value <.05
whereas the difference in end-diastolic velocity between the left and right internal carotid arteries was not significant for both
age groups. Differences between the right and left internal carotid arteries for resistive index
pulsatility index
and pressure
gradient were significant only in the young age group.
Conclusion: We found significant differences between the right and left common carotid and internal carotid arteries in
patients with diabetes and hypertension which were more prominent in the young age group. Values for common carotid IMT
and LD were significantly higher in the left common carotid artery versus the right common carotid artery in both age groups.
Differences between the 2 carotid sides may be attributed to anatomic variations in the common carotid artery origins which
lead to differences in stress between the 2 sides
Age, hypertension, and diabetes can cause significant alterations in arterial structure and function, including changes in lumen diameter (LD), intimal-medial thickness (IMT), flow velocities, and arterial compliance. These are also considered risk markers of atherosclerosis and cerebrovascular disease. A difference between right and left carotid artery blood flow and IMT has been reported by some researchers, and a difference in the incidence of nonlacunar stroke has been reported between the right and left brain hemispheres. The aim of this study was to determine whether there are differences between the right and left common carotid arteries and internal carotid arteries in patient
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(5)
Publication Date
Mon Apr 01 2019
Journal Name
Ieee Transactions On Information Forensics And Security
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