Preferred Language
Articles
/
bsj-7064
A Theoretical Study of the Docking of Medicines with some Proteins
...Show More Authors

A set of ten drug compounds containing an amino group in the structure were determined theoretically. The parameters were entered into a model to forecast the optimal values of practical (log P) medicinal molecules. The drugs were evaluated theoretically using different types of calculations which are AM1, PM3, and Hartree Fock at the basis set (HF/STO-3G). The Physico-chemical data like (entropy, total energy, Gibbs Free Energy,…etc were computed and played an important role in the predictions of the practical lipophilicity values. Besides, Eigenvalues named HOMO and LUMO were determined. Linearity was shown when correlated between the experimental data with the evaluated physical properties. The statistical analysis was used to analyze the descriptors like multiple linear regression analysis performed to derive quantitative structure-activity relationship models which were further evaluated for the values of the prediction. The correlation coefficient gives an excellent relationship of more than (0.980, 0.980, and 0.978) for AM1, PM3, and HF/STO-3G respectively. A docking study was applied for the interaction of medicines with protein. All the drugs were connected with the protein to give the best energy stability for the docking mixtures. Nepafenac (compound No. 8) had the most stable energy with the protein compared with the 4-Aminosalicylic acid (compound No. 2) which had less energy stability.

Scopus Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Mon Apr 24 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
The Relationship between Interleukin-33(IL-33) and Oxidative Stress in Diabetic Patients with Cardiomyopathy
...Show More Authors

   Interleukin -33 (IL)-33 is among IL-1 cytokine superfamily , which shows promise as a biomarker predictive of mortality in diabetic and several cardiovascular disorders in vivo study.The objective of this study  is to investigate the differences in the levels of IL-33 between healthy controls and patients with type 2 diabetes and diabetic cardiomyopathy and to investigate the correlation of IL-33 with HbA1C (biomarkers of type 2 diabetes), hs-CRP  and oxidant –antioxidant status.    One hundred and fifty individuals (age 40-55) were enrolled in this study which was divided into three groups as follows: G1:50 healthy control,G2: 50 subjects with type 2 diabetes mellitus,G3: 50 patients with dia

... Show More
View Publication Preview PDF
Publication Date
Wed May 25 2022
Journal Name
Iraqi Journal Of Science
The Optimal Control Problem for Triple Nonlinear Parabolic Boundary Value Problem with State Vector Constraints
...Show More Authors

       In this paper, the classical continuous triple optimal control problem (CCTOCP) for the triple nonlinear parabolic boundary value problem (TNLPBVP) with state vector constraints (SVCs) is studied.  The solvability theorem for the classical continuous triple optimal control vector CCTOCV with the SVCs is stated and proved. This is done under suitable conditions. The mathematical formulation of the adjoint triple boundary value problem (ATHBVP) associated with TNLPBVP is discovered. The Fréchet derivative of the Hamiltonian" is derived.  Under suitable conditions, theorems of necessary  and sufficient conditions for the optimality of the TNLPBVP with the SVCs are stated and proved.    

View Publication Preview PDF
Scopus Crossref
Publication Date
Sat Mar 28 2020
Journal Name
Iraqi Journal Of Science
Least Squares Estimations for the General Linear Model Parameters with Epsilon Skew Normal Error Term
...Show More Authors

Examination of skewness makes academics more aware of the importance of accurate statistical analysis. Undoubtedly, most phenomena contain a certain percentage of skewness which resulted to the appearance of what is -called "asymmetry" and, consequently, the importance of the skew normal family . The epsilon skew normal distribution ESN (μ, σ, ε) is one of the probability distributions which provide a more flexible model because the skewness parameter provides the possibility to fluctuate from normal to skewed distribution. Theoretically, the estimation of linear regression model parameters, with an average error value that is not zero, is considered a major challenge due to having difficulties, as no explicit formula to calcula

... Show More
View Publication Preview PDF
Scopus Crossref
Publication Date
Thu Dec 01 2022
Journal Name
Ieee Transactions On Human-machine Systems
Myoelectric Control With Fixed Convolution-Based Time-Domain Feature Extraction: Exploring the Spatio–Temporal Interaction
...Show More Authors

View Publication
Scopus (13)
Crossref (11)
Scopus Clarivate Crossref
Publication Date
Tue Aug 01 2023
Journal Name
Baghdad Science Journal
Phytochemical composition, total phenolic content and antioxidant activity of Anadara granosa (Linnaeus, 1758) collected from the east coast of South Sumatra, Indonesia
...Show More Authors

Anadara granosa is a species of the class bivalve commonly found on the east coast of South Sumatra as a fishery commodity. This species has not been widely studied as a source of new bioactive compounds that have antioxidant abilities. This study aims to analyze the antioxidant ability of A. granosa against DPPH radicals and its phytochemical profile qualitatively. Samples were taken at the fishing port of Sungsang Village, South Sumatra, Indonesia. Furthermore, the samples were extracted using ethanol as a solvent and tested for antioxidants against DPPH radicals, total phenol analysis, and preliminary phytochemical test. Based on the antioxidant test results, the IC50 value of the ethanolic extract of

... Show More
View Publication Preview PDF
Scopus (6)
Crossref (1)
Scopus Crossref
Publication Date
Thu Jun 30 2022
Journal Name
Journal Of Economics And Administrative Sciences
Examining the Asymmetric Impacts of Interest and Exchange Rate on Investment in Egypt for the Period 1976-2020: Applying NARDL Model
...Show More Authors

Most of the studies conducted in the past decades focused on the effect of interest rates and exchange rates on domestic investment under the assumption that the independent variables have the same effect on the dependent variable, but there were limited studies that investigated the unequal effects of changes in interest rates and exchange rates, both positive and negative, on domestic investment.  This study used a nonlinear autoregressive distributed lag (NARDL) model to assess the unequal effects of the real interest rate and real exchange rate variables on domestic investment in Egypt for the period 1976 - 2020.  The results revealed that positive and negative shocks for both exchange rates have unequal effects on

... Show More
View Publication Preview PDF
Crossref
Publication Date
Fri May 18 2018
Journal Name
Thesis
The Arabian killifish (Aphanius dispar) as a novel model for mycophysiological studies.
...Show More Authors

Abstract Candida albicans is a commensal fungal pathogen that grows in yeast and hyphal forms in the human gut. C. albicans causes mucosal and cutaneous diseases that can result in significant mortality following systematic infections and it also exhibits drug resistance. Zebrafish have been an excellent model to investigate C. albicans infections because of their transparency and the availability of many transgenic lines. However, there is a limitation in using zebrafish as a model because the fish embryos cannot survive at 37°C therefore it is not suitable for studying Candida infections at physiological relevant human body temperature. In this thesis, the normal embryonic development of Arabian killifish (A. dispar) is investigated, rev

... Show More
Publication Date
Tue Mar 31 2020
Journal Name
College Of Islamic Sciences
(Novelist character in the Iraqi press criticism – Fadhil Thamir as a model))
...Show More Authors

Novel has recently  received the attention of readers and writers greatly, because of the role they play, and this indicates an important rule, which is whenever there is an art or creativity, there must be a respective criticism, and this criticism is certainly not less important than the author. So there are critics who have a prestigious literary position in the follow-up story development, and trying to describe the transformation of its elements. One of these critics is professor Fadhel Thamer, and who wants to approach one of the elements of the novel exploring, must stop on the visions of this critic about it , and that’s why we take the (character) element following the most important opinions of this critic about

... Show More
View Publication Preview PDF
Publication Date
Wed Oct 09 2019
Journal Name
Journal Of The College Of Education For Women
Naber and toning in the modern Arab poetry Mahmoud Darwish, a model
...Show More Authors

Naber and toning in the modern Arab poetry Mahmoud Darwish, a model

View Publication Preview PDF
Publication Date
Wed Jun 01 2011
Journal Name
Journal Of Al-nahrain University Science
A Lexical and Syntax Checker Tool for the Hyper Text Markup Language
...Show More Authors

View Publication
Crossref