Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC-SIGN based on demographic characteristics. Fifty Iraqi RA patients were enrolled in the study, and a control sample of 38 healthy individuals (ascertain by laboratory and clinical tests) were included and matched by gender, age, and ethnicity with the patients. The DC-SIGN concentration was calculated in the patients’ serum and compared to control using the ELISA assay and the results revealed significantly increased serum level of DC-SIGN (12.047 ± 1.114 vs. 6.863 ± 0.806 ng/ml) was recorded in RA patients compared to controls. When correlating results, it was shown that the concentration of DC-SIGN in the serum did not record a significant difference between gender and age, as well as the blood groups. To determine the impact of the therapeutic status in RA patients on the DC-SIGN level, it was found that the concentration of DC-SIGN level was higher in untreated patients compared to treated patients. Regarding viral infection, when an investigation was conducted in RA patients infected with SARS-CoV-2, the serum level of DC-SIGN in RA patients with COVID-19 showed no change in concentrations compared to uninfected RA patients.
The presence of the other representations in the story of modern Arabic
The other who seek to discuss his presence is the other west, and is nothing new to bring the other whatever, especially the Western literature, especially after the opening of the East West and the occurrence of encounters many Whatever the reasons for them or their causes, and the prevalence of the phenomenon influenced by this Western, and therefore his presence in this literature of any had sex. And certainly our presence (we) also in the literature of the other, and this is very natural, created by the convergence of intellectual, cultural and human, which led to the emergence of the cultural theme of conflict between East and West, and these conflicts take d
This paper generalizes and improves the results of Margenstren, by proving that the number of -practical numbers which is defined by has a lower bound in terms of . This bound is more sharper than Mangenstern bound when Further general results are given for the existence of -practical numbers, by proving that the interval contains a -practical for all
جاءت هذه الورقة البحثية لتبين اهمية التلفزيون في حياة النشىء من حيث بناء شخصيته واكسابه مايلزم من المهارات التي تعدهم الاعداد الافضل للحياة في حاضرها ومستقبلها ولتظهر دوره كوسيلة تعليمية معينة يمكن الاستفادة منها في العملية التربويةفي البيت والروضة والمدرسة ولتواكب مراحل حياة الاطفال وخصائص النمو العقلي والجسمي والانفعالي في كل مرحلة
دور المنظمات الدولية في تفسير معاهداتها المنشئة
Academic libraries characterized from other libraries in the groups of literacy acquired, and
ways to retrieve this information, where it is supposed supply of various combinations of traditional
sources, electronic information, such as books and references, maps and indexes, CD-ROMs and
service-line and so on, via electronic mediator or via the Internet instead of the mediator paper. The
digital technology has changed the way you work by academic libraries, where confined to the
primary mission of these libraries to provide prompt services to the needs of researchers, professors
and students, and the provision of reading different materials, including electronic sources that
support the curriculum and research in el
The research aims at showing the media awareness for Students, especially for the students of the preparatory schools through their following the mass media in forming the cultural, educational and political database. It also aims at building a content and prospectives that make them a wide awake stratum that safeguard the society which has faced huge effects of terrorist actions.
Furthermore, it aims at knowing to what extent that students have been acquainted with the printed and electronic newspapers. Finally, it aims at knowing to what extent that they are content with the mass media in covering and
... Show Moreاهتمت دول العالم بدول الساحل الإفريقي لمِا عرفته من ثروات معدنية كثيره فيها، وإن دول الساحل الإفريقي تقع في وسط القارة الإفريقية وإنها تمتد من البحر الأحمر أي مطلة على البحر الأحمر مما يجعلها ذات أهمية ملاحية. والذي زاد في أهميتها مواردها الطبيعية إذ أنها ذات موارد اقتصادية متنوعة وكثيرة لا سيما وأنها قليلة الاستهلاك لهذه الموارد فهذا أدى إلى أهتمام الدول التي يكثر استهلاكها لهذه الموارد فيها، ومن هذه الموا
... Show Moreأساس انتقال المخاطر في عقود التجارة الدولية
Islam was keen to get every man and woman a share of those benefits and wanted to marry and urged him. In order to unite efforts and articulates the arrow and clarifies the goal and I have a share in building a sober Islamic society, for all this and other research title is ((modern or planting and its impact on marital happiness)).