Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC-SIGN based on demographic characteristics. Fifty Iraqi RA patients were enrolled in the study, and a control sample of 38 healthy individuals (ascertain by laboratory and clinical tests) were included and matched by gender, age, and ethnicity with the patients. The DC-SIGN concentration was calculated in the patients’ serum and compared to control using the ELISA assay and the results revealed significantly increased serum level of DC-SIGN (12.047 ± 1.114 vs. 6.863 ± 0.806 ng/ml) was recorded in RA patients compared to controls. When correlating results, it was shown that the concentration of DC-SIGN in the serum did not record a significant difference between gender and age, as well as the blood groups. To determine the impact of the therapeutic status in RA patients on the DC-SIGN level, it was found that the concentration of DC-SIGN level was higher in untreated patients compared to treated patients. Regarding viral infection, when an investigation was conducted in RA patients infected with SARS-CoV-2, the serum level of DC-SIGN in RA patients with COVID-19 showed no change in concentrations compared to uninfected RA patients.
يتناول البحث حماية المستهلك في التعاقد الالكتروني
الانتصار في الحروب الحديثة
كان من مظاهر تأثير اللغة العربية في الفارسية بعد الفتح الإسلامي، القرآن الكريم والحديث الشريف، فتأثر الشعراء والأدباء الإيرانيون بهما وبفنون أقوال العرب عموماً، فاقتبسوا في أشعارهم وكتاباتهم الفارسية أو العربية منها، كثيراً من الآيات والأحاديث والمصطلحات العربية، وهذا الاقتباس هو فنّ أدبي ينتمي الى المحسنات اللفظية والتي تشكّل مع المحسنات المعنوية عُنصُري علم البديع الذي هو فرع من ثلاثة علوم الى جانب عل
... Show Moreأهمية البحث والحاجة أليه
لماذا الأهتمام بالشخصية ؟
- بسبب الواقع العالمي المنكوس حيث بات الأنسان يعيش غريباً معزولاً عن أعماق ذاته ، ويحيا مقهوراً من أجل الوسط المادي الذي يعيش فيه .
- أن خلاص الأنسانية الأكبر لن يكون ألا بالنمو الروحي والعقلي للأنسان ، وتحسين ذاته وأدارتها على نحو أفضل ، وليس في تنمية الموارد المحدودة المهددة بالهلاك .
- أن ت
الانتخابات والتحول الديمقراطي في العراق
The Internet makes the world like a small village. It has the ability to make groups of the same ideas, thoughts, and identity close to each other by gathering them in one place. It is a way to communicate and share information and opinion; shaping and sharing of comprising individuals with common interests and the participation of individuals in a fruitful dialogue results in achieving a set of goals promote ideas and mobilizing people about issues and events of common interests.
To address the relationship of the internet via interactive communication and its ability to achieve social capital and discuss issues and various social events, the study sees that the problem of the study could be formulated as follows:
Consid
... Show More That it is essential to be for us to recognize is that the phenomenon of poverty are addressed most of the doors of Arab countries in general and Iraq in particular, with the contrast between Qatar and another, and that the deteriorating situation of developing countries it is clear that poor people are victims of exploitation and inequality.
That dealing with the phenomenon of poverty should be more present in mind, especially since the Arab world that enters the era of so-called globalization, as more people poor, and the increase of the utilization of materials Arab interests abroad under the competition is unequal and the impoverishment of deliberate environmental and resource Arab
ضمانات الاستثمار في حقول الغاز
Özet
Türkiye türkçesinde ''Anlam bilimi (Semantik)'' tezin ana konusu ve dilin adlandırma ve sınıflandırma incelemesini ele alır. Türk dilbilimcilerine göre bu dilbilimlerin şubesine bir tanım sunar. Semantik, tarih bakımından başlanlangıcı, oluşunu ve geliştirmesini de inceleniyor.
Bu konu ile ilgili yayınlanmış olan bazı tezlerin de alındı. Türk dilbilimcilerin görüşünu Mehmet Hengirmen, Konay Karaağaç, Sezai Güneş, Fuat Bozkurt ve Hüseyin Atay ve diğerlerdir.
Bu tez anlam bilimi dalların özellikleri ve anlam değiştirmesi
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