Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC-SIGN based on demographic characteristics. Fifty Iraqi RA patients were enrolled in the study, and a control sample of 38 healthy individuals (ascertain by laboratory and clinical tests) were included and matched by gender, age, and ethnicity with the patients. The DC-SIGN concentration was calculated in the patients’ serum and compared to control using the ELISA assay and the results revealed significantly increased serum level of DC-SIGN (12.047 ± 1.114 vs. 6.863 ± 0.806 ng/ml) was recorded in RA patients compared to controls. When correlating results, it was shown that the concentration of DC-SIGN in the serum did not record a significant difference between gender and age, as well as the blood groups. To determine the impact of the therapeutic status in RA patients on the DC-SIGN level, it was found that the concentration of DC-SIGN level was higher in untreated patients compared to treated patients. Regarding viral infection, when an investigation was conducted in RA patients infected with SARS-CoV-2, the serum level of DC-SIGN in RA patients with COVID-19 showed no change in concentrations compared to uninfected RA patients.
(لا مجتمــــع الا وبـــــه قـــــانو ن ) مقولـــــه اطلقهـــــا فقیـــــه رومـــــا القدیمـــــة ( شیشـرون ) فالقـانون لـیس ولیـد الیـوم وانمـا منـذ بـدء الخلیقـة بـدأت حاجـة الانسـان الـى قواعـد سـلوكیه یـنظم بهـا حیاتـه ویـرى بهـا حـدود حریتـه بحیـث لاتتجـاوز هـذه الحریة الى حدود حریة الاخرین٠واذا كانـــت المؤسســـیة ودولـــة القـــانون مـــن اهـــم معـــاییر الانتمـــاء الـــى العصر الحـدیث یـأت الخ
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او هو حسن الخلق وفعل المكارم
او الظرف وحسن التناول
او الالتزام لما يندب له الانسان(1) .
وقد كثر استخدام هذه اللفظة في التراث فقيل ادب الطبيب ، وادب الوزير، وادب القاضي ، وادب المائدة ، وادب الخط ، وادب المعلم والمتعلم ، وادب المعلم في نفسه وفي درسه ،وادب المتعلم مع استاذه وادب البحث والدرس.
The news of some of the Arab palaces that built in the Islamic cities were scattered in historical sources and references and was talking about the engineering and technical wonders that characterized these palaces, and Perhaps the purpose of mentioning its (often) was to show the extravagance and luxury that reached the palaces as a kind of condemnation of this act or to make visitors admire its masterpieces
Continued Ottoman rule in the Arab world until the end of World War I in 1918, and during the four centuries of Ottoman control, care of the Ottomans install and floating their rule, and to prevent the Arabs from the establishment of a political entity separate from the people to facilitate the rule of the Arab world and to ensure the
This paper deals with the meaning of cultural interaction in the hadith &also foundation that prophet (peace on him) followed through his invitation & rejecting all forms of injustice, oppression & racial discrimination.
The science of jurisprudence of the most honorable science, and engaged in the great reward with God Almighty; Today, they strive to highlight this tremendous wealth by searching for it, studying it, realizing it and presenting it to mankind for the purpose of benefiting from it.
It is a blessing to me that guided me to write in jurisprudence on the subject: (Delayed dowry in Islamic jurisprudence) Islamic law has preserved the rights of the wife to her husband, which is a financial and moral right. It is one of the provisions of the marriage contract and not a health condition and therefore marriage is held without mentioning in the contract.
This research aims to highlight the prophetic approach in civilized coexistence, and to show what society was like in the time of the Prophet, and specifically after the sakha and the writing of the newspaper (prophetic document) which established the rules of civilized coexistence, and there is no doubt that God almighty created all nations and different peoples according to Human nature, this difference has been recognized by the duty of coexistence and acquaintance without abolishing each other, coexistence and recognition of the other and respect for its particularities result in a state of dialogue between cultures and civilizations and paves the way for their meeting instead of clashing, as well as contributing coexistence to make
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