Rheumatoid arthritis (RA), is an autoimmune, and inflammatory disease that is closely related to the destruction of cartilage and bone. DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. Therefore, the purpose of this study is to determine the serum level of DC-SIGN in RA patients, as well as the level of DC-SIGN based on demographic characteristics. Fifty Iraqi RA patients were enrolled in the study, and a control sample of 38 healthy individuals (ascertain by laboratory and clinical tests) were included and matched by gender, age, and ethnicity with the patients. The DC-SIGN concentration was calculated in the patients’ serum and compared to control using the ELISA assay and the results revealed significantly increased serum level of DC-SIGN (12.047 ± 1.114 vs. 6.863 ± 0.806 ng/ml) was recorded in RA patients compared to controls. When correlating results, it was shown that the concentration of DC-SIGN in the serum did not record a significant difference between gender and age, as well as the blood groups. To determine the impact of the therapeutic status in RA patients on the DC-SIGN level, it was found that the concentration of DC-SIGN level was higher in untreated patients compared to treated patients. Regarding viral infection, when an investigation was conducted in RA patients infected with SARS-CoV-2, the serum level of DC-SIGN in RA patients with COVID-19 showed no change in concentrations compared to uninfected RA patients.
This study has pursued to identify the agricultural initiative (the independent variable) with all its subordinate variables in profits and bank lending activity (the dependent variable), as an applied study in cooperative agricultural bank, which stemms from a problem that includes:-
- The policy variance of agricultural initiative lending and variation of the cooperative agricultural bank lending policies.
- decreasing the demand on the loans of the cooperative agricultural bank and increasing the demand on the agricultural initiative by the individuals (citizens).
The purpose of the study is represented by clarifying the practical reality of applying the agricultural initiative and its
... Show MoreThe life insurance companies need a sound system to use it in selecting Insurable risks so they can avoid or reduce possible losses that may be insured to a minimum levels , But the application within IRAQI INSURANCE COMPANY reflects that it still depends on a traditional ways in the procedures used to select that risks .
This research represents an attempt to put acceptable suggestions about developing a system for selecting insurable risks which used now by iraqi insurance company by recognizing the risks of life insurance , determining kinds of risks which can difined as normal and upnormal risks , rectification of the
... Show MoreThe research aims to identify the academic problems of family counseling diploma students at Saudi Universities. In addition, to identify the differences in these problems according to gender, marital status, place of study, academic specialization, and GPA. The sample consisted of (491) students. The researcher has used one questionnaire for academic problems prepared by the researcher. The research revealed the following results: There were academic problems among family counseling diploma students at Saudi Universities, the most problems were related to the systems and administrations of the university, then the field training, the buildings, classrooms and campus facilities, then the academic courses, after that the exams, then
... Show Moreان المشكلة البحثية تتحدد في ان المهام والادوات التي تملكها السلطة التنفيذية، من الصعوبة تركها من دون رقابة، والرقابة والتقييد ياتي من اطراف عدة، واهمها: السلطة التشريعية، فالبرلمان في العراق منح اختصاصات للنظر في اعمال واداء السلطة التنفيذية بما يضمن تقيدها بالدستور الاتحادي. والهدف من هذا البحث هو الاشارة الى اهمية الاختصاصات الممنوحة للبرلمان العراقي، بما يضمن التاسيس لدولة القانون، اي وجود مرجعية قانو
... Show Moreمن الاهداف المهمة لتدريس الكيمياء في المرحلة الثانوية التعرف على الثروات الطبيعية وكيفية استغلالها والاستفادة منها (وزارة التربية والتعليم ,1970)ومن اهداف تدريس الكيمياء التي يشير اليها المختصون ,مساعدة الفرد على التكيف الايجابي والناجح مع بيئة بما يحدث لمكوناتها مع تغير وما يدخل على بنيتها من عوامل مستجدة (كاظم ,1973) على ان يتم ذلك من خلال الشعور الايجابي لدى الافراد بدفعهم للاسهام في تطوير البيئة من
... Show MoreThe research dealt with the financial policies adopted by Almurabitin (484-520 / 1092-1143) and Almuahadin (540-620 / 1145-1223) in Andalusia, their characteristics, and how they dealt with increasing the resources of Bayt Almal and organizing the spending process. The first axis of the research discussed the policies of the management of public funds in the provinces of Almurabitin and Almuahadin in Andalusia. While the second presented to the most prominent and most important resources of Andalusia financial in the era of these two countries such as Zakat, Alkhiraj, Alghanayim, confiscations and illegal taxes and others. The third axis reviewed the public spending policies of the two countries and the political and military conditions
... Show Moreشغلت الإشاعة حيزا مهما من اهتمام العلوم الاجتماعية وكانت مادة بحث في علم النفس الفردي وعلم النفس الاجتماعي وعلم الاجتماع والسياسة. ويأتي هذا الاهتمام الكبير والمتواصل بالإشاعة لآثارها الخطيرة على حياة الأفراد والمجتمعات في أوقات السلم والحرب.
النظام السياسي في تركيا وايران