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bsj-6431
Predictive Significance of Interleukins 17A and 33 in Risk of Relapsing–Remitting Multiple Sclerosis
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Cytokines are signaling molecules between inflammatory cells that play a significant role in the pathogenesis of a disease. Among these cytokines are interleukins (ILs) 17A and 33, and accordingly, the current case-control study sought to investigate the role of each of the two cytokines in the risk of developing multiple sclerosis (MS). Sixty-eight relapsing-remitting MS (RRMS) Iraqi patients and twenty healthy individuals (control group) were enrolled. Enzyme linked immunosorbent assay (ELISA) kits were used to determine serum levels of IL-17A and IL-33. Results revealed that IL-17A and IL-33 levels were significantly higher in MS patients than in controls (14.1 ± 4.5 vs. 7.5 ± 3.8 pg/mL; p < 0.001 and 65.3 ± 16.3 vs. 49.3 ± 20.0 pg/mL; p < 0.001, respectively). Receiver operating characteristic (ROC) curve analysis demonstrated that IL-17A was a very good predictor of MS (area under curve [AUC] = 0.869; 95% CI = 0.779 - 0.960; p < 0.001; cut-off value = 10.2 pg/mL; sensitivity = 80.8%; specificity = 75.0%). A similar prediction was presented by IL-33, but the AUC value was lower (AUC = 0.762; 95% CI = 0.63 - 0.89; p < 0.001; cut-off value = 56.4 pg/mL; sensitivity = 70.6%; specificity = 70.0%). Multinomial logistic regression analysis confirmed the significance of IL-17A and IL-33 in MS risk, and under three models of analysis, the estimated odds ratios for IL-17A (1.50, 1.49 and 1.50, respectively) and IL-33 (1.05, 1.05 and 1.06) were above 1.0. Patients stratified by gender (male and female), expanded disability status scale (EDSS: < 3 and ≥ 3) or medication (pre- and post-medication) showed no significant differences in serum levels of IL-17A and IL-33 for each stratum. However, with regard to response to medication, it was found that responding patients showed significantly higher levels of IL-33 than non-responders (70.9 ± 12.2 vs. 57.2 ± 18.2 pg/mL; p = 0.018). This difference was not observed when considering IL-17A. Pearson correlation analysis between IL-17A and IL-33 revealed that both cytokines were not significantly correlated. In conclusion, the study indicated that IL-17A and IL-33 were up-regulated in serum of MS patients, and this up-regulation was not influenced by age, gender, EDSS or medication status, but the elevated level of IL-33 was more pronounced in patients who responded to medication.

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Publication Date
Wed Jun 22 2022
Journal Name
Arab Science Heritage Journal
الإمام علي الهادي(ع) دراسة تحليلية في السيرة والمنهج
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God bestowed upon the Imams of the Ahl al-Bayt (peace be upon them) knowledge and wisdom, in addition to give them virtue as long as it was not given to anyone from the worlds. knowledge have been enriched from them that cause pride.

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Publication Date
Sat Jan 01 2000
Journal Name
مجلة العلوم الزراعية العراقية
تاثير بعض اوساط النمو في نمو وتزهير نبات الراننكيل
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Publication Date
Thu Sep 30 2021
Journal Name
College Of Islamic Sciences
Islam's position on freedom according to John Stuart Mill
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The issue of freedom is the most prominent and distinctive issue of Western thought, which it reached after a long struggle. The English thinker John Stuart Mill is considered the most prominent Western thinker who elaborated on the issue of freedom, until his ideas on the issue of freedom became the semi-final formula for issues of freedom in Western thought, which revolve in their entirety on The individual has complete freedom as long as it does not harm others, and this freedom is controlled by law.

And if the freedoms he offered were not considered an achievement in Western thought; Freedom in Islam is a central and fundamental issue, and the details of freedoms in Islam have not been accomplished by anyone, but rather came

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Publication Date
Sun Jul 07 2013
Journal Name
Journal Of Educational And Psychological Researches
دور الاسرة العراقية في غرس المنظومة القيمية لدى ابنائها
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The family is e Social first come into contact with filial friction direct and continuing as is the social environment the first to grow the patterns of socialization that make up the life of the individual in the future , especially in forming the personality of both social and cultural , the family's work to lay the foundations of standards called the system value , which is ( religious teachings - customs - traditions - norms ) and is on its way interaction values ​​between family members as well as the transfer of expertise , knowledge and models of behavioral by parents to their children , which will be in accordance with the type of interactions and social relations is also affected dev

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Publication Date
Wed Mar 30 2022
Journal Name
Arab Science Heritage Journal
الري والإصلاح الزراعي في العراق (1-132هـ/ 622-750م)
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The organization and development of the irrigation system and agrarian reform in Iraq had an impact on the diversity of its methods and uses.

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Publication Date
Mon Jan 23 2023
Journal Name
Arab Science Heritage Journal
ظاهرة المفارقة في كتاب بلاغات النساء دراسة بلاغية اسلوبية
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The Arab woman expressed the life of oppression that she suffers from in her masculine environment, as she expressed her linguistic abilities with eloquence and intelligence, as she did not neglect philosophy, wisdom,

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Publication Date
Sun Oct 01 2006
Journal Name
Journal Of Educational And Psychological Researches
الكفايات التدريسية اللازمة لمدرسي التربية الإسلامية في المرحلة الإعدادية
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مشكلة البحث :

إن القرآن الكريم هو النور المبين والذكر الحكيم يحتوي على الغاية الأسمى التي تهدف اليها الإنسانية ، فهو روح التربية الإسلامية وهو المنهج القديم الذي تستمد منه فلسفتنا التربوية واتجاهاتها ،                                        (الزوبعي ، 1974: 18)

إن الدين الإسلامي هو نظام الهي

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Publication Date
Sun Oct 02 2011
Journal Name
Journal Of Educational And Psychological Researches
صلابة الشخصية وعلاقتها بتقدير الذات لدى التدريسيين في الجامعة
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     يتركز محور مشكلة البحث الحالي حول مفاهيم أساسية تعكس مكامن القوة في الشخصية الإنسانية وما لها من دور مؤثر على الواقع النفسي والمادي للفرد عموماً وهذه المفاهيم هي صلابة الشخصية، وتقدير الذات,ويتحدد مفهوم الصلابة من خلال مظاهر الشخصية وأسلوبها الذي تتميز به في التعامل مع الواقع وكيفية إدراكها وما تتمتع به من خبرات نفسية وتجارب حياتية داخلية تعكس مدى الوعي بالمستجدات الموقفية التي تصادفها

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Publication Date
Thu Oct 01 2015
Journal Name
Journal Of Educational And Psychological Researches
دور الإرشاد النفسي في تحقيق جودة الحياة بالمجتمع المعاصر
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     Psychological Counseling Services occupies a high position in the developed countries and that for its psychologist services for different sectors of the community members, and has been popularized until recently the wrong concept of the effect, that the psychological service is provided only to the owners of behavior is normal only, Vantage him neglect to provide psychological services a large segment of the community members who are in dire need of these services.

      The counseling service is part of a global social movement seeking to emphasize the quality of life of the human and the emphasis on the value and dignity and the need to live a quiet lif

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Publication Date
Wed Nov 28 2018
Journal Name
Arab Science Heritage Journal
بابل بابل في العصر الشبيه بالكتابي وعصر فجر السلالات
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This study deals with the region of the Babylon governorate in Iraq during the Proto-Literate and Early Dynastic periods. It is the region of the well- known ancient capital Babylon. The earlier period includes Late Uruk, Jamdat nasr, and the first epoch of the Early Dynastic period. The latter includes the second and third epochs of the Early Dynastic period. The both periods had lasted more than one thousand years (3500-2334 BC

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