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bsj-6431
Predictive Significance of Interleukins 17A and 33 in Risk of Relapsing–Remitting Multiple Sclerosis
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Cytokines are signaling molecules between inflammatory cells that play a significant role in the pathogenesis of a disease. Among these cytokines are interleukins (ILs) 17A and 33, and accordingly, the current case-control study sought to investigate the role of each of the two cytokines in the risk of developing multiple sclerosis (MS). Sixty-eight relapsing-remitting MS (RRMS) Iraqi patients and twenty healthy individuals (control group) were enrolled. Enzyme linked immunosorbent assay (ELISA) kits were used to determine serum levels of IL-17A and IL-33. Results revealed that IL-17A and IL-33 levels were significantly higher in MS patients than in controls (14.1 ± 4.5 vs. 7.5 ± 3.8 pg/mL; p < 0.001 and 65.3 ± 16.3 vs. 49.3 ± 20.0 pg/mL; p < 0.001, respectively). Receiver operating characteristic (ROC) curve analysis demonstrated that IL-17A was a very good predictor of MS (area under curve [AUC] = 0.869; 95% CI = 0.779 - 0.960; p < 0.001; cut-off value = 10.2 pg/mL; sensitivity = 80.8%; specificity = 75.0%). A similar prediction was presented by IL-33, but the AUC value was lower (AUC = 0.762; 95% CI = 0.63 - 0.89; p < 0.001; cut-off value = 56.4 pg/mL; sensitivity = 70.6%; specificity = 70.0%). Multinomial logistic regression analysis confirmed the significance of IL-17A and IL-33 in MS risk, and under three models of analysis, the estimated odds ratios for IL-17A (1.50, 1.49 and 1.50, respectively) and IL-33 (1.05, 1.05 and 1.06) were above 1.0. Patients stratified by gender (male and female), expanded disability status scale (EDSS: < 3 and ≥ 3) or medication (pre- and post-medication) showed no significant differences in serum levels of IL-17A and IL-33 for each stratum. However, with regard to response to medication, it was found that responding patients showed significantly higher levels of IL-33 than non-responders (70.9 ± 12.2 vs. 57.2 ± 18.2 pg/mL; p = 0.018). This difference was not observed when considering IL-17A. Pearson correlation analysis between IL-17A and IL-33 revealed that both cytokines were not significantly correlated. In conclusion, the study indicated that IL-17A and IL-33 were up-regulated in serum of MS patients, and this up-regulation was not influenced by age, gender, EDSS or medication status, but the elevated level of IL-33 was more pronounced in patients who responded to medication.

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Publication Date
Sat Aug 10 2013
Journal Name
Journal Of Accounting And Financial Studies (jafs)
التهرب الضريبي واثره على التنمية الاقتصادية في العراق
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Highlights the role of taxes in being a major source of funding sources internal economic and social development, and then, any decrease in tax revenue caused by tax evasion, for example, would weaken the government's ability to finance their investments and core financing private sector investment as a result of reduced ability to increase their reserves's cash banks, as well as the weakening of the effectiveness of tax evasion taxes as a tool to guide economic activity in the framework of service for development, and to achieve justice. And the statement of the reasons for and methods of evasion mandated to pay the tax due on them, whether legitimately or illegal with the statement of the proposed methods to tackle tax evasion and elimina

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Publication Date
Sat Jan 01 2005
Journal Name
Journal Of The College Of Languages (jcl)
LA TRANSGRESSION CHEZ RIMBAUD Lecture de I' aspect de Transgression dans Marine
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LA TRANSGRESSION CHEZ RIMBAUD Lecture de I' aspect de Transgression dans Marine

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Publication Date
Tue Oct 23 2018
Journal Name
Journal Of Planner And Development
اساسيات (التنظيم المكاني –الاجتماعي ) في تخطيط المجمعات السكنية
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Publication Date
Mon Jul 22 2019
Journal Name
Arab Science Heritage Journal
سة الشخصيات في رواية القضية تنتصر"لبنت الهدى
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قسّم الباحث الشخصيات في هذ ا البحث إلى أقسام: اإيجابية والسلبية
والسطحية...ثم تطرقا إل خصوصياتها النفسيّة وبينا مقصود الكاتبة، وتطرّقا إلی الغزو
الثقافي الغربي ،

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Publication Date
Sun Aug 30 2020
Journal Name
Arab Science Heritage Journal
حرية المرأة في فكر نزيهة الدليمي (دراسة تاريخية)
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    This research discussed the freedom of Iraqi women in the thought of Dr. Nazeeha Al-Dulaimi.

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Publication Date
Sun Jul 03 2016
Journal Name
Journal Of Educational And Psychological Researches
توظيف الشخصية في القصيدة الجديدة/ حميد سعيد انوذجا
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This poem is regarded an important Harmonized structure in modern and Contemporary Culture to achieve aqualitative poem Comported with the other cultural structures inorder to discover the ego and aspiration in shaping distinctive voices.
The Iraqi poetry is affected tangibly by this poem because of the intellective vaccinating between Iraqi and Arab poets ingeneral and western cultures in particular as a result of the tranplahin movement and other important means.
The modern poet wood to ask some important characters to enrich his technician text inspite the fact that this is not a new way in Arab poetry but it takes avarant – criented to become outside the limits of rigid description within ongoing kinematic structure to be in

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Publication Date
Wed Jan 02 2008
Journal Name
Political Sciences Journal
اثر المحددات الخارجية والداخلية في بناء االدولة لعراقية
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اثر المحددات الخارجية والداخلية في بناء الدولة العراقية

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Publication Date
Sun Jan 02 2005
Journal Name
Political Sciences Journal
واقع ومستقبل الصراعات الدولية والاقليمية في البحر الاحمر
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واقع ومستقبل الصراعات الدولية والاقليمية في البحر الاحمر

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Publication Date
Sun Oct 06 2019
Journal Name
دار الضياء للطباعة والتصميم
موسوعة الدراسات العاملية في المجال الرياضي ( الجزء الثاني )
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أن الكتاب في مجال الاختبارات والقياس والإحصاء الرياضي والذي صيغ بطريقة مبسطة وعلى وفق الفعالية التي تم تناولها بالبحث والدراسة سواء أكانت الدراسة في الجانب البدني أو المهاري أو الوظيفي للعبة أو تبحث في المواصفات الجسمية من ناحيتي القياسات والأدلة الجسمية وكل بصورة منفردة ، أو بصورة دراسة مركبة من ناحية تناول القياسات الجسمية مع المتغيرات البدنية لفعالية ما على سبيل المثال وتناولهما في دراسة واحدة أو تناول

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Publication Date
Sun Jan 03 2010
Journal Name
Journal Of Educational And Psychological Researches
أثر برنامج تنموي في الاستعداد الكتابي لطفل الروضة
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مشكلة البحث وآهميته :

تعد مرحلة ما قبل المدرسة من المراحل شديدة الأهمية في نمو الأطفال في هذه المرحلة تمتد رغبة الطفل في التعرف على العالم المحيط به ثم تتطور أنشطته لتصبح أكثر عمقا وأتساعا فتتضمن البيئة البعيدة عنه ، هذا فضلا على أن 50% من التنمية الذهنية للطفل تتشكل في السنوات الأربع الأولى من العمر وأن القراءة هي إحدى المكونات الأساسية التي تعززهذا الجانب من التنمية .

( أبو

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