There are many animal models for polycystic ovary (PCO); using exogenous testosterone enanthate is one of the methods of induction of these models. However, induction of insulin resistance should also be studied in the modeling technics. Therefore, the present study aims to investigate the expression of insulin receptor substrate (Irs)-2 mRNA in the liver tissue of rat PCO model. Nineteen Wistar rats were divided into three groups; (1) PCO modeling group (N =7) received daily 1.0 mg/100g testosterone enanthate solved in olive oil along with free access dextrose water 5%, (2) vehicle group (N =6), which handled like the PCO group, but did not receive testosterone enanthate, (3) control group (N =6) with standard care. All the animals were administered via intra-peritoneal injection for 14 days. Expression of Irs-2 mRNA was studied with real-time PCR and fold changes (FC) were reported. The average of expression in the control group was considered as the calibrator. About 13.4% expression reduction was found in the PCO group (FC =0.874, P-value =0.043). No significant reduction was found in the vehicle group (FC =0.951, P-value =0.076). However, analysis of variance did not show a significant difference between all the groups of study (P-value =0.085). The present model of PCO might induce insulin resistance at liver level with a low effect size via reduction in the mRNA expression of Irs-2. Study of the involved genes and molecules in other tissues of PCO animal models is suggested.
There was a huge role in the history of a muslim woman and several books have mentioned that politically or in religion and even scientifically and socially which leaded a lot of women to look up to these women who helped in keeping the religion just in the right form for other generations
اهتمام العلماء العرب بالحروف مبينين معانيه موضحين مقاصده
That the Jewish minority in Iraq, were considered among the Iraqi people, building.
Violence can be identified as an outreaching on others’ dignity,
freedom, properties, and life. Therefore, violent actions cannot be determined
only on materialistic attacks such as killing, beating, robbery, rape, and civil
wars, but it also includes the verbal attacks such as insult, threat, and cursing.
Violence against women can be identified as any bad actions that are
done against women, which lead to a physical or psychological harm, and
invade their safety and freedom whether these actions come from men or
women, against one woman or a group of women in special and general
places.
Before, the social, historical and lawful manners concentrated on
sexual distinction between the men and a woman, which
البنية الاقتصادية الاجتماعية للادارة الجديدة في الولايات المتحدة الامريكية
The research aimed at measuring the degree to which the accept their class environment in governmental & civil Kindergartens & it also aimed at knowing the differences between the dimensions of the measurement & the differences according to the kindergarten & class variables .
The researcher made a measurement for the class environment & it included five dimensions & the answering choices were three ( to a big extent , to some extent and no ) and after making sure that the measurement is usable , the researcher applied it on the sample which consisted of ( 212 )male & female children through the estimated answers of the teacher & the result was that there was an accep
... Show MoreTürklerin İslam dini ve kültürünü benimsedikten sonra,Anadolu'da Arap ve özellikle Fars Edebiyatlarını örnek alarak oluşturdukları yazılı edebiyattır. Bu dönemin şairleri(ozanları) şiirlerini divan adı verilen kitaplarda topladıkları için söz konusu edebiyata da Divan Edebiyatı denilmiştir.Özellikle,medreseden yetişen aydın sanatçı ve yazarların saray ve çevresinde oluşturdukları bir edebiyat geleneği olduğu için, Havas(Yüksek Zümre) edebiyatı,Saray edebiyatı, Klasik Türk edebiyatı gibi adlarla da anılmaktadır.Divan edebiyatı sözünün 1900'den sonra ortaya çıktığı sanılmakta ve ilk defa kimin kullandığı bilinmemektedir.
Human wealth is the most valuable wealth on the face of the earth, and building the intellectual, cultural and scientific human being is the greatest process carried out by all religions and philosophies at all times, and the divine law aimed at reforming the earth, including in order to preserve this great wealth, and to preserve its existential and qualitative entity.
يهدف البحث إلىبيان دور الانتاج الانظف وتأثير تطبيقه على تكاليف الوحدة الاقتصادية وادواته وتقنياته التي تساهم في دعم الميزة التنافسية المستدامة
هدف البحث إلى التعرف على اصالة الذات فضلاً عن التعرف على الفروق في اصالة الذات بين الطلبة على وفق متغير الجنس (ذكر – انثى) والتخصص الدراسي (علمي – انساني) والمرحلة الدراسية (أول- رابع)، تألفت عينة البحث من (140) طالبا وطالبة من طلبة جامعة الموصل-كلية التربية الاساسية، وتم تطبيق مقياس البحث - مقياس (اصالة الذات) وهو (من إعداد الباحثة)، وقد اسفرت نتائج البحث عن: - إن طلبة الجامعة يتمتعون بأصالة الذات. - عدم وجود فروق في
... Show More