Ghrelin and leptin are hunger hormones related to type 2 diabetes mellitus (T2DM), and the pathogenesis of T2DM is the abnormality in insulin secretion and insulin resistance (IR). The aim of this study is to evaluate ghrelin and leptin concentrations in blood and to specify the relationship of these hormones as dependent variables with some biochemical and clinical measurements in T2DM patients. In this study, forty one T2DM and forty three non-diabetes mellitus (non-DM) subjects, aged between 40-60 years and with normal weight, were enrolled. Fasting serum ghrelin and leptin were estimated by enzyme-linked immunosorbent assay (ELISA). In our results ghrelin was significantly increased, and leptin was significantly decreased, in T2DM patients compared with non-DM subjects. Ghrelin was positively correlated with the fasting blood glucose (FBG) and IR, but inversely related to the insulin sensitivity (IS). Leptin was negatively correlated with mean arterial pressure (MAP), FBG, glycated hemoglobin (HbA1c), IR, low-density lipoprotein cholesterol, nitric oxide (NO), and alanine aminotransferase (ALT), as well as showed a linear correlation with IS and a strong dependence on sex. The area under the curve (AUC) value shows ghrelin and leptin as biomarkers for T2DM. In conclusion ghrelin and leptin hormones have predictive ability to predict T2DM, as they are significantly associated with IR, IS, free radicals, and lipid profile.
Highlights the role of taxes in being a major source of funding sources internal economic and social development, and then, any decrease in tax revenue caused by tax evasion, for example, would weaken the government's ability to finance their investments and core financing private sector investment as a result of reduced ability to increase their reserves's cash banks, as well as the weakening of the effectiveness of tax evasion taxes as a tool to guide economic activity in the framework of service for development, and to achieve justice. And the statement of the reasons for and methods of evasion mandated to pay the tax due on them, whether legitimately or illegal with the statement of the proposed methods to tackle tax evasion and elimina
... Show MoreMeans the current research to study the organization formal and its role in demonstrating aesthetic values of the publications issued by the Telecommunications Company (Asia Cell) in Iraq, where is the organization the formal need for a mission to find the concepts and dimensions of the functional and expressive and aesthetic added to the impact of the actor in achieving the goals set for the publication.
The target is determined by the researcher to disclose the role of formal organization to show the aesthetic values of the publication to reach scientific results
The social support is considered one of the most important constituents of
society and the one which can ensure its unity.
The resources of social support are different accordind to the variety and
the multiplication of the net – work of the social relationships that are
established among the individuals. The importance of this variable is evident
in the emolional adaptation and the mental health as well as its role in mitigating of the illness threating and in accelerating the recovery. social support can enhance the individuals ability to tolerate and face the emotional
and physical problems in the time of cris and stressful life conditions.
The most important results are shown as follows :
1- It was
تعد اللغة العربية العامة من المواد التي تدرسها الطالبات في الصف الأول في كل أقسام كلية التربية للبنات، وقد لاحظ الباحث إن الطالبات يفتقرن الى التعرف الى معاني كثير من الكلمات التي ترد في المقطوعات الأدبية الشعرية منها والنثرية التي يقدمها أستاذ المادة، وبما إن وقت المحاضرة محدود فأنه لا يسمح بالتعرف الى أفكار الطالبات حول معاني هذه الكلمات وقد يضطر الأستاذ أخيرا الى تقديم المعاني جاهزة للطالبات من اجل
... Show Moreيسلط هذا البحث الضوء على ظاهرة لغوية، والتي يطلق عليها تسمية "التضاد". يبين هذا البحث مفهوم هذه الظاهرة، خصائصها، أنواعها، وأسبابها، في اللغتين الساميتين: السريانية والعبرية. حيث تم اعتماد المنهج المقارن في دراسة هذه الظاهرة اللغوية وتبيان وجوه التشابه واالختالف في ماهية هذا النوع من المفردات، أي األضداد، في اللغتين: السريانية والعبرية. ويشير البحث إلى نوعين من التضاد وهما: التضاد الذي يكون بين مفردتين مستقل
... Show MoreThere are many opinions about modern political thoughts for future , trying to draw a map of strong powers in the world and one of these thoughts is the conflict with civilizations. Both of these phenomena search for future and western civilization. It is important to mention that Islamic civilization has special place and clear effect through its conditions.
המחקר מתייחס לתופעת ההקטנה משני ענפים את הסימנטיקה והמורפופונולוגיה בשפה העברית, ומנסה ליגלוי את המשמעות בתוך ההקשר של צורות ההקטנה לדוגמאות מן התורה טקסטים מחדשות, שירה וסיפורים, הרי שחלק מהמשמעויות של מבנה הפלט עומדות בניגוד למשמעויות הבסיס או הדרגה במשמעות, כך מביעות על (הקטנה, חיבה, או זלזול) שרובן לא התקיימו בעברית הקלאסית, מצד אחר המחקר בדק במבנים המורפולוגיים במייוחד (המשקלים של צורת ההקטנה) ומבחין את
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مشكلة البحث وآهميته :
تعد مرحلة ما قبل المدرسة من المراحل شديدة الأهمية في نمو الأطفال في هذه المرحلة تمتد رغبة الطفل في التعرف على العالم المحيط به ثم تتطور أنشطته لتصبح أكثر عمقا وأتساعا فتتضمن البيئة البعيدة عنه ، هذا فضلا على أن 50% من التنمية الذهنية للطفل تتشكل في السنوات الأربع الأولى من العمر وأن القراءة هي إحدى المكونات الأساسية التي تعززهذا الجانب من التنمية .
( أبو
... Show MoreThose human societies, which based on pluralism and cultural diversity, can be handled with completely consciously، when converting the contradiction to integration and the collision to coexistence and the transition from intolerance to tolerance. This diversity in communities make individuals differ acconding to the following:
1- The requirements of human nature.
What linguists mentioned about the infinitive and its use in the linguistic levels of speech, whether with its verb, or what was mentioned in the difference between the infinitive and the noun of the source, are matters that are related to the phenomenon of hearing in speech, a need necessitated by the nature of the linguistic law