Ghrelin and leptin are hunger hormones related to type 2 diabetes mellitus (T2DM), and the pathogenesis of T2DM is the abnormality in insulin secretion and insulin resistance (IR). The aim of this study is to evaluate ghrelin and leptin concentrations in blood and to specify the relationship of these hormones as dependent variables with some biochemical and clinical measurements in T2DM patients. In this study, forty one T2DM and forty three non-diabetes mellitus (non-DM) subjects, aged between 40-60 years and with normal weight, were enrolled. Fasting serum ghrelin and leptin were estimated by enzyme-linked immunosorbent assay (ELISA). In our results ghrelin was significantly increased, and leptin was significantly decreased, in T2DM patients compared with non-DM subjects. Ghrelin was positively correlated with the fasting blood glucose (FBG) and IR, but inversely related to the insulin sensitivity (IS). Leptin was negatively correlated with mean arterial pressure (MAP), FBG, glycated hemoglobin (HbA1c), IR, low-density lipoprotein cholesterol, nitric oxide (NO), and alanine aminotransferase (ALT), as well as showed a linear correlation with IS and a strong dependence on sex. The area under the curve (AUC) value shows ghrelin and leptin as biomarkers for T2DM. In conclusion ghrelin and leptin hormones have predictive ability to predict T2DM, as they are significantly associated with IR, IS, free radicals, and lipid profile.
The Chain's experience of reform and development monopolized with deep and exclusive concerns of the world.
Starting from the academic departments of universities and researches and study centers to the world's organizations and institutes passing through the government and the official systems in many countries that get affected , positively or negatively, now or later by china's economic development .
Searching in the china's experience of reform and development is important because it takes place in a developing country in which the leadership is succeeded in choosing the right methodology an model of changing and operating economics, making use of all the past national a
... Show Moreاهتم العديد من الباحثين والمحققين في دراسة أبي البركات الأنباري ، كونه أديبا ولغويا ومفسرا ، ونشروا معظم ما وصل إلينا من مؤلفاته ،لكن كما يبدو أن الانباري، مؤرخا ، لم ينل حظه من الاهتمام والدراسة على الرغم من أن كتابه (نزهة الألباب في طبقات الأدباء) قد نشر وحققه صفوة المحققين ([i])وذلك انهم أغفلوا التعريف بمنهجه ودراسته لاسيما وأن التأليف في كتب الطبقات من أهم مناهج الكتابة التاريخية
... Show MoreThe manuscript (Tuhfat al-Ashab wa Nuzhat al-Albab) by the author Ahmed bin Ibrahim al-Hanafi al-Srouji (d. 0ٓٔ AH / ٖٓٔٔ
AD), one of the important manuscripts because it is an encyclopedia characterized by the diversity of its topics
The Andalusi woman’s poetry forms a point upon which there has been much vagueness and prejudice may be because of the distorted versions that have recorded the women’s heritage. The
في مدينة الري القريبة من طهران الحالية ولد ابو بكر محمد بن يحيى بن زكريا الرازي سنة 251هـ/865 م وسميً بالرازي نسبة الى مدينة الري 0 أحب الرازي الغناء والضرب على العود في بداية حياته ثم هجر ذلك كله واتجه الى الطب والكيمياء 0 درس الطب في شبابه في بغداد وقد اخطأ بعض المؤرخين في ظنهم ان
- The problem of infertility considers one of the chronic problem a which faced the
individual & families equally . This problem causes a negative effects in psychological ,
social and development fields. The infertility contributes in weakening the human
development, when the human development has become as a centre point which centered
about individual preparing , rehabilitation, training and knowledge toreach to the required
excellence.
We think that , the infertility destroys the socially development; therefore the socially and
scientific institutions are working hard to find successful solution to resolve the problem
infertility through sophisticated and scientific methods. This problem
يبخث البحث في عملية انهاء وتصفية الوجود المالي للشركة ودور المصفي في انهاءه واعطاء كل ذي حق حقه
Аннотация: В данной статье исследуется проблема семантики текстовой парадигмы как одного из активных вопросов языковой науки о тексте, рассматриваются семантические отношения и их роль в раскрытии тех смысловых связей, на основе которых можно отличать типы семантических отношений «синонимия, антонимия, полисемия», выдвигается положение о семантических отношен
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