Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
تعدُّ القارة الإفريقية ذات موقع جيوسياسي إذ إنه يربط دول العالم بعضها ببعض، وأنّها تحتوي على ثلث الاحتياط النفطي المؤكد العالمي واليوريانيوم والمعادن الأخرى مما جعلها ذات أهمية للدول العظمى، وأنّها غير مستقرة سياسياً إذ تكثر بها النزعات والهجمات الإرهابية مما جعل الدول العظمى تتسابق لوقف المشاكل، ومن أهم هذه الدول العظمى هي فرنسا التي تحتفظ بنفوذها السبق أي الاستعماري في القارة وأنّها لا تتنازل عنه لأي دو
... Show MoreIn this research I like to shed light on the mind because of its importance because it is what distinguishes Human from all other animals and that the question and status comes from his role in the formulation of knowledge and science where the machers agreed that the word of mind in its general sense is the source of thought and thought and the instrument of faith and philosophy , Then to the statement of the various stages pass
... Show Moreيتناول البحث الحماية المدنية للمستهلك في المرحلة السابقة على التعاقد الالكتروني
this research talks about the weakness that had happened in the construction of the sentences which effected on the syntactic meaning . it considers an important problems faced the languages .
يُعد الذكاء الاصطناعي من العلوم الحديثة التي ارتبطت بالإنسان منذ العقود الخمسة الماضية، وأصبحت السياسة الرقمية جزءاً لا يتجزأ من المجتمع لكونها تُستعمل في أغلب مجالات حياة الإنسان. وهذا ما شجع صانعي السياسات التكنولوجية الجديدة في التفكير بكيفية توظيفه لخدمة مصالحهم العليا السياسية والاقتصادية، بغض النظر عن بذل الجهود للتفكير في تنظيمهم للذكاء الاصطناعي التوليدي، ووضع قيود تراعي التشريعات الدينية، وقوا
... Show MoreAmong the imams who honor the soil of Iraq by embracing their remains is Imam Al-Qasim Ibn al-Imam Musa Ibn Ja'far ibn Muhammad ibn Ali ibn al-Hussein ibn Ali ibn Ali ibn Abu Talib, Amir of the believers Al-Kadhim (may peace be upon him ), the mother of the sons and the mother of his brother Imam Ali ibn Musa al-Rida (may peace be upon him), buried in the Holy QOM (1)It is one of the doors of need for Shiite Muslims All the stories of imams are similar in terms of injustice
The research includes a bout IL- IQulle , and their role in scientific of the Islamic – Arabic civilization , for Dr. Khlood M.Namma the proff in the collage of education for woman , Baghdad university , History department
The Arab woman expressed the life of oppression that she suffers from in her masculine environment, as she expressed her linguistic abilities with eloquence and intelligence, as she did not neglect philosophy, wisdom,
Rights of child in the community crisis Iraqi child model The study aimed to identify the types of violation against children in the Iraqi crisis as well as to develop community coping mechanisms to these violations and promote the rights of the child health psychological , social and legal . the first chapter discusses the research problem and its importance and purpose of the research problem and its importance and purpose of the research and the most important terms in the A- Rights of the child ,B- crisis , chapter 2 rights of the child ensure the historical roots , of children’s rights in the holy quran and the sunnah, and legal rights through the twentieth century and the beginnings of century xx, the se through the twentieth cen
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