Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
Alienation, and Westernization and away, whether forcibly sense exile or voluntary in the sense of migration, it will generate nostalgia, and a sense of overwhelming homesickness spatial or alienation spiritual (emotional) and perhaps alienation resulting from exile or forced deportation by the authority
Each of the languages possesses a set of phenomena that researchers in its sciences should stop at to explain the secrets of this language, including the phenomenon of idiomatic expression. Perhaps this phenomenon may constitute an obstacle to non-native speakers of the language or even the native speakers themselves. The Arabic language is full of these expressions, Which needs us to dedicate its own studies to it so that we can collect it in a dictionary that includes and collects it with explanation and interpretation of its semantics
ارتبط الانسان بالطبيعة بأشكالها المختلفة ارتباطا وثيقا ، فهي تمثل الحاضنة له بمجالات حياته كلها، فما كان من الأدباء الا أن يجعلوها في كثير من الأحيان مادة لأدبهم وأرضية خصبة لنتاجهم، فتمظهرت بصورها المختلفة وحاجة الانسان لها وخيرها وشرها في الأدب على مدى التاريخ، والعرب شأنهم شأن غيرهم من الأمم فمنذ عصر ما قبل الاسلام كانت الطبيعة منفذا مهما وملجأ للشعراء في انتاج الأدب وابداعه وإلى يومنا هذا، ونحن إذ نتحد
... Show MoreDue to the great technical developments in the field of informational knowledge, technological and productive changes and intense competition among institutes in the era of globalization, focus of these institutes on the notion of total quality management has been increased. Quality costs have represented an essential ratio of the production costs, a matter that requires preparing information about these costs, Because of that, the need for preparation and availability of accounting information system to measure and prove these costs has been emerged.
The descriptive analytic method has been used here to answer the questions raised in this study. Among the results that have been reached
... Show Moreيسلط هذا البحث الضوء على ظاهرة لغوية، والتي يطلق عليها تسمية "التضاد". يبين هذا البحث مفهوم هذه الظاهرة، خصائصها، أنواعها، وأسبابها، في اللغتين الساميتين: السريانية والعبرية. حيث تم اعتماد المنهج المقارن في دراسة هذه الظاهرة اللغوية وتبيان وجوه التشابه واالختالف في ماهية هذا النوع من المفردات، أي األضداد، في اللغتين: السريانية والعبرية. ويشير البحث إلى نوعين من التضاد وهما: التضاد الذي يكون بين مفردتين مستقل
... Show MoreThis research aims to understand the main problems and family
commitments faced by working women, and make proposals that would stop or
lessen them, the researcher made questionnaire , applied on a sample of (20)
university female teachers, the study showed that the main problems in respect to
their importance as: Anxiety of leaving children at home alone, the weak role of the
nurseries and kindergartens in taking care of the children, relative large number of
children per family which would lead to more commitments, and the unavailability
of convenient working arrangement for working mothers.
The essential objective of this study presents a analyzes of the combination of reality and fantasy in three dramas of Spanish author Alejandro Casona. "Trees die standing" (premiered in Buenos Aires in 1949), “Prohibited suicide in spring” (premiered in Mexico in 1937) and "The boat without fisherman" (premiered in Buenos Aires in 1945).
The first part is an introduction about the biography of Spanish author Alejandro Casona that will allow us to understand some peculiarities of his work in relation to the social historical context of his time.
In the second part of this study we have analyzed elements of reality and fantasy in the th
... Show MoreThe intellectual and revolutionary movements that have emerged since the beginning of the second half of the first century of the Islamic era did not appear suddenly, but must have preceded by a social consciousness, multi-forms, in the forefront of class awareness and religious awareness, and awareness was more painful, Of the society of the Arabian Peninsula - before Islam - feel it and suffer from it, a sense of injustice and tyranny, oppression and humiliation, and the destruction of dignity as well as poverty and hunger, and the injustice of tribal laws, and tyranny of each other and the tyranny of their heads on the tribes members and families belonging to this tribe or hill
تعد رواية (غراب الطاهرة ) من الروايات المعاصرة التي ركزت على الواقع المعاصر، وهي تمثل حقلاً بكراً صالحاً لدراسة العلاقة الحميمة بين ( الواقع ) و ( الشكل البنائي ) وأثره في بنية النص الروائي، بمعنى آخر دراسة القوانين التي توجه أنماط التأليف، وحرية الأختيار في صياغة العمل الفني.إذ إن اهتمام المؤلف بالتوثيق التاريخي، وتسجيل أهم المظاهر الواقعية، ومايرتبط بها من ممارسات النظام السابق أثرت في البناء الروائي، فمن حي
... Show More