Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
הקדמה
עיון זה מטפל ביסוד עיקרי במבנה השירי, כלומר הצורה השירית, המהווה את היסוד הבולט והחשוב ביותר
בשירה, אין שיר בעל ערך אמנותי שלא מכיל צורה שירית יפה.
העיון הזה כולל מבוא על הצורה השירית , בו הצגנו דעות של מבקרים ערביים ומערביים בולטים ביחס הנושא ,
למען הגשת צורה מפורשת להבנת מבנה הצורה השירית . סקרנו את היסודות העיקריים שנשענה עליהם
הצורה השירית ומהן: הדמיון, הדמוי, מטאפורה, סמל, סיפקנו הסבר מפורט על
The aim of the research is to estimate the hidden population. Here، the number of drug users in Baghdad was calculated for the male age group (15-60) years old ، based on the Bayesian models. These models are used to treat some of the bias in the Killworth method Accredited in many countries of the world.
Four models were used: random degree، Barrier effects، Transmission bias، the first model being random، an extension of the Killworth model، adding random effects such as variance and uncertainty Through the size of the personal network، and when expanded by adding the fact that the respondents have different tendencies، the mixture of non-random variables with random to produce
... Show MoreBy taking a quick look at the glory history of our nation and the current reality of it, we find that the difference is clear between how we used to be and what we have become. This is what I call the regression of civilization that happened to our Muslim nation.
The moral implications and value in the philosophy of education are one of the most important topics that should be well worth seeking out, especially in our time because of its great importance in the upbringing of the emerging formation, guidance and evaluation within the system or graded him the values of the society in which they live.
هذه الدراسة محاولة جادة لفهم تطور التعليم في كربلاء المقدسة خلال المدة 1958-1968، تناول البحث محاور عدة، ابتدأ في رياض الاطفال، ومن ثم التعليم الابتدائي في كربلاء، فالتعليم الثانوي. اعتمد التربية، التخطيط، الارشاد، فضلاً عن عديد الكتب التي اعتمدت الوثائق والتي سيجدها القارئ في ثبت المصادر.
The codification of the social history of the city of Baghdad will be filled with an inherited folklore and folklore that has been descended to it from the previous generations with all its tales of folk tales, metaphors, parables, crafts and industries. Immortal
الإسھام في عَ وْ د محمود إلی علم المعاني لیحل ّ محلّھ الصحیح في أذھان المتعلّمین وفي الدراسات النقدیة والبلاغیة .وعلم المعاني یرتكز على طورین لا یمكن مفارقة أوّ لھما إذا بقیت الضبابیّة تلفّھ ،لأنھ مفتاح مغالیق الطور الثاني الأھم ، والطوران ھما ) القواعد والأصول ( و)التحلیلاتُ إلى والرؤى البلاغیة (، وقواعد علم المعاني یفارقھا الفھم في أحیان كثیرة ، لذا وجّ ھتقصد المشاع والبسیط من المخزون النحوي لتنحیة خفائھا وف
... Show Moreنتيجة لتزايد القلق إزاء استقرار القطاع المالي عموماً والقطاع المصرفي على وجه الخصوص ، سعت منظمات دولية متخصصة عديدة إلى توافر قواعد ارشادية (مرجعية) Benchmark يمكن الاهتداء بها في تقييم فعالية أنظمة المراقبة المصرفية بعد الإدراك على نطاق واسع أن نقاط الضعف في الأنظمة المصرفية كانت إحدى المسببات الرئيسة للازمات المالية في بلدان عدة خلال العقد الأخير . ونتيجة للعولمة فالأزمات المصرفية التي تحدث في وقتنا هذا ت
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