Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks the first among the population and the leading cause of cancer related female mortality. This study is designed to investigate the correlations between serum and tissue markers in order to clarify their role in progression or regression breast cancer. Tumor Markers are groups of substances, mainly proteins, produced from cancer cell or from other cells in the body in response to tumor. The study was carried out from April 2018 to April 2019 with total number of 60 breast cancer women. The blood samples were collected from breast cancer women in postoperative and pretherapeutic who attended teaching oncology hospital of the medical city in Baghdad and the serum markers evaluated by ELISA technique are Carbohydrate Antigen 15-3 (Ca 15-3), Carbohydrate Antigen 27.29 (Ca 27.29), Anti-Mullerian Hormone (AMH), Tumor Necrosis Factor-Alpha (TNF-α), Interleukin-6 (IL-6), Interleukin-10 (IL-10) and Human Epidiymis Protein-4 (HE4). Tissue samples were collected for the same breast cancer women who attended medical city, Baghdad with total number 30. The tissue markers evaluated by Immunohistochemical technique are Estrogen Receptor (ER), Progesterone Receptor (PR), Human Epidermal Growth Factor Receptor 2 (Her 2/neu) and Cyclin E. The results showed a positive significant correlation (p = 0.017) between Ca 27.29 and Her-2/neu, (p = 0.038) between IL-6 and cyclin E phenotype, (p = 0.051) between TNF-α and Cyclin E intensity, (p = 0.005) between HE4 and Her-2/neu, and negative significant correlation (p = 0.058) between IL-10 and ER score and (p = 0.045) between HE4 with Cyclin E intensity. We conclude from these correlations that positive correlations increasing disease progression, like correlation between Ca 27.29 and Her-2/neu, cyclin E with IL-6 and cyclin E with TNF-α. And the negative correlations may contribute to delay disease, like correlation between IL-10 and ER. From the correlations results in this study, it is clear that the Ca 27.29, Her-2 / neu, cyclin E markers play an important role in disease progression.
نشط مسمىّ ( آية السيف ) مع الآية الخامسة من سورة براءة ( التوبة ) آخر السور نزولاً , وهو مسمّى شديد الصولة أفضى إلى إشكالية في فهم فلسفة الجهاد من منظور الشرع الإسلامي , إذ شكّلت الآية منطلقاً وركيزة لمقولات العنف التي تبنّتها الجماعات المتشدّدة بتوثيقات منبتها من التراث تلتقط صور الأحداث بإبتار وتقطيع , تقابلها توثيقات تربأ عمّا يقع في أوّل الخاطر، وتلك عرضتها في محورين , السياق المقامي الذي أظهر انضباط أحكام ال
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ظهر التقييس كمفهوم لقياس الضرائب وتحديد الأجور والرواتب منذ مدة ليست طويلة وتم استخدامه في العديد من بلدان العالم. ولاجل تحقيق العدالة في توزيع الدخول ورفع المستوى المعيشي لذوي الدخول المحدودة، اذ يتطلب من الدولة إتباع أسلوب التقييس للأجور والرواتب للموظفين ،إضافة إلى استخدام التقييس في فرض الضرائب وتحديد السماحات اعتمادا على مستوى التضخم في الاقتصاد. خاصة وان الهدف الأساسي من إتباع أسلوب التقييس هو
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Benim tezimin adlı "Namık kemal'ın Hikayelerinde isim hal ekleri"dir. Bu tezde ilk olarak Namık kemal'ın hayatı hakkında bilgi vermeye çalıştım. Sonra isim hal ekleri hakkında bilgi de verdim. Sonra Namık kemal'ın hikayelerinde geçen isim hal ekleri birer birer çıkarmaya çalıştım.
XIX yüz yılında en önemli dönem Tanzimat dönemidir. Tanzimattan beri yeni hayat ihtiyaci ile yeni sanat anlayışı, birçok yeni kelime ve tamlamaların ortaya çıkıp, yerleşmesine sebep olmuştur. Namık kemal'ın mektuplarındaki birçok kelimeler, fikirler, kavramlar ve inanışlar, hepsi yeni değildir. Çoğu yaşıyan dilde kullanıyor, bir kısmı da sözlüklerde bulunuyordu. Fakat bi
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تعـد الوحـدة الوطنيـة لأي شـعب قاعـدة الارتكـاز للبنـاء الحضـاري والتقـدم والتطـور والتنميـة في المجـالات كافـة وبغيابها يفقد الشعب المرتكزات الأساسية لآمنه واستقراره، وقدرته على احتواء الأزمات الناشئة عن الاختلافات العرقيـة والدينية والطائفية، وعلى هذا الأساس فان قيادات الشعب الوطنية يكون هاجسها الدائم الحفاظ على الوحدة الوطنية، وسـد كـل الثغـرات والمنافـذ في جـدرانها لكـي لاتنفـذ مـن خلالهـا ريـاح
... Show MoreAcademic libraries characterized from other libraries in the groups of literacy acquired, and
ways to retrieve this information, where it is supposed supply of various combinations of traditional
sources, electronic information, such as books and references, maps and indexes, CD-ROMs and
service-line and so on, via electronic mediator or via the Internet instead of the mediator paper. The
digital technology has changed the way you work by academic libraries, where confined to the
primary mission of these libraries to provide prompt services to the needs of researchers, professors
and students, and the provision of reading different materials, including electronic sources that
support the curriculum and research in el