Ebastine (EBS) is a poorly water-soluble antihistaminic drug; it belongs to the class II group according to the biopharmaceutical classification system (BCS). The aim of the present work was to enhance the solubility, dissolution rate and micromeritic properties of the drug, by formulating it as spherical crystal agglomerates by Quasi Emulsion Solvent Diffusion (QESD) method.

Spherical crystal agglomerates (SCAs) were prepared in presence of three solvents dichloromethane (DCM), water and chloroform as a good solvent, poor solvent and bridging solvent respectively.  Agglomeration of EBS involved the use of some hydrophilic polymers like polyethylene glycol 4000 (PEG 4000), polyvinyl pyrrolidine K30 (PVP K30), D-?-tocopheryl

Nowadays nanoparticles are used in many fields of life all over the world, and there are numerous ways to obtain them: chemical, physical and biological processes. In recent times, the biological method for the synthesis of nanoparticles associated with using plant extract is widely spread. Optimal conditions for synthesis of silver nanoparticles using aqueous seeds extract of Myristica fragrance were highlighted in this research, such as type of plant extract, weight of extracted plant material, volume ratio of plant extract to AgNO3 and temperature of reaction. The study proved that the optimal status for AgNPs synthesis by using 10 g of M. fragrance seeds powder were added to 100 mL boiled distilled water, then homogenized and filt

     The problem of reconstruction of a timewise dependent coefficient and free boundary at once in a nonlocal diffusion equation under Stefan and heat Flux as nonlocal overdetermination conditions have been considered. A Crank–Nicolson finite difference method (FDM) combined with the trapezoidal rule quadrature is used for the direct problem. While the inverse problem is reformulated as a nonlinear regularized least-square optimization problem with simple bound and solved efficiently by MATLAB subroutine lsqnonlin from the optimization toolbox. Since the problem under investigation is generally ill-posed, a small error in the input data leads to a huge error in the output, then Tikhonov’s regularization technique is app

Nuclear medicine is important for both diagnosis and treatment. The most common treatment for diseases is radiation therapy used against cancer. The radiation intensity of the treatment is often less than its ability to cause damage, so radiation must be carefully controlled. The interactions of alpha particle with matter were studied and the stopping powers of alpha particle with ovary tissue were calculated using Beth-Bloch equation, Zeigler’s formula and SRIM Software also the range and Liner Energy Transfer (LET) and ovary thickness as well as dose and dose equivalent for this particle were calculated by using Matlab language for (0.01-200) MeV alpha energy.

ليس جديداً القول بان هناك حاجة مستمرة ومتزايدة لاستخدام البيانات الاقتصادية المتسقة عن القطاعات المختلفة في الاقتصاد القومي لدعم وإسناد عملية التحليل الاقتصادي وتطوير النماذج الاقتصادية الكلية.

وتعرض مصفوفة الحسابات القومية Social Accounting Matrix  (SAM) اطاراً شاملاً من المعلومات الأساسية لهذا النوع من النماذج والتحليل. فهي تتضمن كلا من المستخدم- المنتج
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طريقة مقترحة لانشاء تصاميم القطاعات غير الكاملة المتزنة BIBD بتوظيف الخوارزمية الجينية الوراثية

    The ground state densities of neutron-rich (¹¹Be,¹⁵C) and proton-rich (⁹C,¹²N,²³Al) exotic nuclei are investigated using a two-body nucleon density distribution (2BNDD) with two frequency shells model (TFSM). The structure of the valence one-neutron of ¹¹Be is in pure (1p_1/2) and of ¹⁵C in pure (1d_5/2) configuration, while the structure of valence one-proton configuration is in ⁹C,¹²N are to be in a pure (1p_1/2) and ²³Al in a pure  (2s_1/2) . For our studied nuclei, an efficient (2BNDD) operator for point nucleon system folded with two-body correlation operator's functions is  u

The use of Right dihedral method, Lisle graph, and Mohr diagram allows the analysis of the paleostress. Fault slip data were measured for eighteen data of two stations located within Chia Gara structure in Dohuk area in the High Folded Zone, Northern Iraq. Depending on Mohr diagram, Bott equation, and vertical thickness, the magnitudes of the paleostress at the time of the tectonic activity were determined. Firstly, Georient Software was used to estimate the orientation of the paleostresses (σ1, σ2 and σ3). Secondly, using the rupture –friction law, taking into account the depth of the overburden, the vertical stress (σv) was calculated to determine the magnitude of the paleostresses in the study area. The values in st

A numerical evaluation of the crucial physical properties of a 3D unsteady MHD flow along a stretching sheet for a Casson fluid in the presence of radiation and viscous dissipation has been carried out. Meanwhile, by applying similarity transformations, the nonlinear partial differential equations (PDEs) are transformed into a system of ordinary differential equations (ODEs). Furthermore, in the numerical solution of nonlinear ODEs, the shooting method along with Adams Moulton method of order four has been used. The obtained numerical results are computed with the help of FORTRAN. The tables and graphs describe the numerical results for different physical parameters which affect the velocity and temperature profiles.