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Formulation Characterization and Evaluation of Meloxicam Nanoemulgel to be Used Topically
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Meloxicam is a non-steroidal anti-inflammatory drug. It is practically insoluble in water. It is associated with gastrointestinal side effects at high doses on long  term treatment. The aim of this investigation to formulate and evaluate gellified nanoemulsion of meloxicam as a topical dosage form to enhance meloxicam therapeutic activity and reduce systemic side effect.

The pseudo ternary phase diagrams were made, including  the oil mixture which is composed of almond oil and peppermint oil at a ratio (1:2), variable surfactant mixture (S mix) which are tween 80 and ethanol at ratios of (1:1, 2:1, 3:1, and 4:1) and double distilled water. Slow dripping of double distilled water to the combination  of the oil mixture and Smix was performed to get nanoemulsion. The pseudo ternary phase diagram that has a greater nanoemulsifying area was contained  Smix ratio (3:1) from which seven formulas of nanoemulsion (NE1-NE7) were taken for characterization of prepared nanoemulsions and to prepare nanoemulgel formulas (NF1-NF7). The seven nanoemulgel formulas were subjected to various evaluations. NF1 was the selected formula and investigated for its stability and morphology.

Atomic force microscopy (AFM) indicated that the optimized formula (NF1) was nanosized particle nearly spherical in shape and smooth surface globules, this indicates  stability of optimized nanoemulgel (NF1). It can be concluded that the selected formula (NF1) is an effective alternative for the topical delivery of meloxicam.

Keywords: Meloxicam, Nanoemulgel, Arthritis.    

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Publication Date
Tue Jan 31 2017
Journal Name
Journal Of Engineering
Behavior of Reinforced Concrete Columns Subjected to Axial Load and Cyclic Lateral Load
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Columns subjected to pure axial load rarely exist in practice. Reinforced concrete columns are usually subjected to combination of axial and lateral actions and  deformations, caused by  spatially‐complex loading patterns as during earthquakes causes lateral deflection that in turn affects the horizontal stiffness. In this study, a numerical model was developed in threedimensional nonlinear finite element and then validated against experimental results reported in the literatures,
to investigate the behavior of conventionally RC columns subjected to axial load and  . lateral reversal cyclic loading. To achieve this goal, numerical analysis was conducted by using finite element program ABAQUS/Explicit. The variables co

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Publication Date
Thu Nov 01 2012
Journal Name
Iraqi Journal Of Science
THE EVOLUTION OF PLANETARY NEBULAE(PN) AND FADING TIME ACCORDING TO SYNTHETIC MODEL
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Abstract Planetary nebulae (PN) represents the short phase in the life of stars with masses (0.89-7) M☉. Several physical processes taking place during the red giant phase of low and intermediates-mass stars. These processes include :1) The regular (early ) wind and the envelope ejection, 2) The thermal pulses during Asymptotic Giant Branch (AGB ) phase. In this paper it is briefly discussed how such processes affect the mass range of Planetary Nebulae(PN) nuclei(core) and their evolution, and the PN life time, and fading time for the masses which adopted. The Synthetic model is adopted. The envelope mass of star (MeN ) and transition time (ttr) calculated respectively for the parameter (MeR =1.5,2, 3×10-3 M☉). Another time scale is o

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Publication Date
Tue Dec 01 2020
Journal Name
Iraqi Journal Of Physics
Pulsed laser deposition to investigate structural and optical properties of lead sulfide nanostructure
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In this work, the structure properties of nano Lead sulfide PbS thin films are studied. Thin samples were prepared by pulse laser deposition and deposited on glass substrates at wavelength 1064nm wavelength with a various laser energies (200,300,400,500)nm. The study of atomic force microscope (AFM) and X-ray diffraction as well as the effect of changing the laser energy on the structural properties has been studied. It has been observed that the membrane formed is of the polycrystalline type and the predominant phase is the plane (111) and (200). The minimum grain size obtained was 16.5 nm at a laser energy about 200 mJ. The results showed that thin films of average granular sizes (75 nm) could be prepared.As for the optical properties,

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Publication Date
Thu Mar 30 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Synthesis of New Opioid Analgesic Peptide Analogues to Enkephalin (Leucine- and Methionine-Enkephalin)
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A small number of researches were done in the design and synthesis of enkephalin analogues that are able to resist degradation effect of proteolytic enzymes with good bioavailability and half-lives.Through studying structure activity relationships we tried to incorporate phthalyl group, tryptophan and lysine amino acids in different positions in the basic backbone structure of the naturally occurring opioid Leu5- and Met5- enkephalin, in the hope that such insertion of these amino acids could induce interesting addition in the biological activity of these analogues with enhancement of their bioavailability, in addition to decrease side effects as addiction liability.

These synthesized peptides are:

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    Publication Date
    Thu Jun 30 2011
    Journal Name
    Al-khwarizmi Engineering Journal
    Characterization of Delamination Effect on Free Vibration of Composite Laminates Plate Using High Order Shear Deformation Theory
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     A dynamic analysis method has been developed to investigate and characterize embedded delamination on the dynamic response of composite laminated structures. A nonlinear finite element model for geometrically large amplitude free vibration intact plate and delamination plate analysis is presented using higher order shear deformation theory where the nonlinearity was introduced  in the Green-Lagrange sense. The governing equation of the vibrated plate were derived using the Variational approach. The effect of different orthotropicity ratio, boundary condition and delamination size on the non-dimenational fundamental frequency and frequency ratios of plate for different stacking sequences are studied. Finally th

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    Publication Date
    Wed Aug 31 2022
    Journal Name
    Al-kindy College Medical Journal
    Towards a Better Dacryocystorhinostomy, Evaluation of Multimodal Surgical Techniques in Nasolacrimal Duct Obstruction
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    Background: This study aimed to evaluate the outcome of long-term results of dacryocystorhinostomy (DCR) techniques in specialized eye care center in Iraq.

    Subjects and Method: This is a prospective study of 650 patients from July 2014 to July 2019 with nasolacrimal duct obstruction in Ibn Al Haitham Eye Teaching Hospital. A preoperative questionnaire was done, then one month, three months, six months and one year postoperatively. The success of surgery defined as follow; Absence of epiphora completely, Resolve of dacryocele or mucocele or any new attack of daryocystitis, Appearance of fluorescein dye from nose in fluorescein disappearance test, Successful irriga

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    Publication Date
    Sat Nov 03 2018
    Journal Name
    Iraqi National Journal Of Nursing Specialties
    Evaluation of Nursing Care Management for Diabetes Mellitus Patient with Total Hip Replacement
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    Objective: The aim of the study to evaluate the nursing care management for diabetes mellitus patient
    with total hip replacement after fractured hip.
    Methodology: A field study carried out on patients with diabetes mellitus and have total hip
    replacement after fractured hip in orthopedic ward at the hospital of surgical specialization (malefemale)during
    January 2002 to January 2003.Physical and psychological nursing
    assessment
    immediately after the surgery was done for the both subjects (control and experimental) and then a
    scientific management with daily nursing care were provided to the experimental subject with daily
    nursing care to the patient condition by using a scientific and practical methods and leave th

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    Publication Date
    Fri Dec 14 2018
    Journal Name
    Iraqi National Journal Of Nursing Specialties
    Evaluation of Diabetes Self-Management among Patients in Baghdad City: A Comparative Study
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    Objective(s): To Evaluate Diabetes self –management among patients in Baghdad City and to compare
    between these patients self-management relative to the type of the disease.
    Methodology: A descriptive design was conducted in Baghdad city, started from November 16th 2017 to the
    end of May 17 th 2018 in order to evaluate Diabetes self-management. Purposive (non-probability) sample,
    which was consisted of (120) patients who were diagnosed with D.M. The sample is comprised of (60) patient
    with diabetes type I and (60) patient with diabetes type II. It is consisted of (60) male and (60) female. A
    questionnaire is constructed for the purpose of the study. It is composed of (42) items. Reliability and validity of
    the ques

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    Publication Date
    Mon Jan 25 2021
    Journal Name
    Engineering And Technology Journal
    Performance evaluation of Photovoltaic Panels by a Proposed Automated System Based on Microcontrollers
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    Publication Date
    Thu Feb 13 2020
    Journal Name
    Thesis
    IMPLICATION OF GEOMECHANICAL EVALUATION ON TIGHT RESERVOIR DEVELOPMENT / SADI RESERVOIR HALFAYA OIL FIELD
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    IMPLICATION OF GEOMECHANICAL EVALUATION ON TIGHT RESERVOIR DEVELOPMENT / SADI RESERVOIR HALFAYA OIL FIELD