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Evaluation of the Role of Interleukein-2 and Interleukein-4 in the Immunopathogenesis of Steroid Therapy Resistance in Iraqi Asthmatic Patients
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Interleukins (IL-2 and IL-4) are increased in asthmatics and were reported to induce resistance to steroid therapy in some patients who fail to get benefit from glucocorticoids when used in full dose and for long period of time. In this context, the present study was conducted on Iraqi patients to provide additional laboratory mean, beside the clinical diagnosis, for the decision whether the asthma is steroid sensitive or resistant by monitoring the level of immunoglobulins, complement proteins and interleukins among asthmatic patients (steroid sensitive or resistant) and the possible contribution of other factors like age, sex and environments in the development of steroid resistance. A total number of 55 asthmatics and 28 normal subjects were enrolled in the study. Patients were diagnosed clinically as steroid sensitive (SSA) and steroid resistant (SRA) and blood samples were taken from all subjects included in the study for the measurement of immunoglobulins (IgA, IgG, IgM and IgE), complement proteins (C3 and C4), interleukins (Il-2 and Il-4), and total and differential WBC counts.The results showed no age, sex and residence dependency of acquired steroid resistance, while smoking habit (and may be the atopic allergy) constitute marked predisposing factors. The level of IgA and IgE were high in both SRA and SSA, while IgG level was low in SRA. Complement proteins (C3 and C4) were not differ in asthmatic patients in comparison with control group. The interesting results were those concerning interleukins. The levels of IL-2 and IL-4 were very high in SRA than in SSA. These are parallel with high lymphocyte and neutrophil counts in blood samples of those patients.In conclusion, beside clinical diagnostic features concerning the dose and duration of therapy with glucocorticoids, monitoring the levels of IL-2 and IL-4 could provide additional laboratory diagnostic measures for the convincing decision that asthma is steroid resistant.

Key words: steroid resistant asthma, steroid sensitive asthma, IL-2, IL-4

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Publication Date
Tue Jun 01 2021
Journal Name
Int. J. Nonlinear Anal. Appl.
Fibrewise totally compact and locally totally compact spaces
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In this paper we define and study new concepts of fibrwise totally topological spaces over B namely fibrewise totally compact and fibrwise locally totally compact spaces, which are generalization of well known concepts totally compact and locally totally compact topological spaces. Moreover, we study relationships between fibrewise totally compact (resp, fibrwise locally totally compact) spaces and some fibrewise totally separation axioms.

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Publication Date
Fri Jun 30 2023
Journal Name
نسق
Semiotic Isotopy and Its Effect on Reading Comprehension
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Publication Date
Fri Jun 20 2025
Journal Name
Ournal Of Kufa For Chemical Sciences
Hemorrhagic Fever history, Diagnosis and Treatment: review article
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hemorrhagic fever (VHF), one of which is Filoviridae. The Filoviridae family includes the Ebola virus , is responsible for the current VHF outbreak in West Africa. Viral hemorrhagic fevers (VHFs) occur in various regions around the world, yet traditional diagnostic testing for these diseases has typically been conducted in major reference laboratories located in Europe and the United States. In this review, we explore the current understanding of the mechanisms driving the pathogenesis of viral hemorrhagic fevers (VHFs) and examine the progress in developing preventive and therapeutic strategies for these infections.

Publication Date
Sun Jun 20 2021
Journal Name
Baghdad Science Journal
Multifactor Algorithm for Test Case Selection and Ordering
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Regression testing being expensive, requires optimization notion. Typically, the optimization of test cases results in selecting a reduced set or subset of test cases or prioritizing the test cases to detect potential faults at an earlier phase. Many former studies revealed the heuristic-dependent mechanism to attain optimality while reducing or prioritizing test cases. Nevertheless, those studies were deprived of systematic procedures to manage tied test cases issue. Moreover, evolutionary algorithms such as the genetic process often help in depleting test cases, together with a concurrent decrease in computational runtime. However, when examining the fault detection capacity along with other parameters, is required, the method falls sh

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Publication Date
Tue Nov 30 2021
Journal Name
Journal Of The Indonesian Mathematical Society
e*-Hollow-Lifting and Cofinitely e*-Lifting Modules
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Publication Date
Mon Jul 14 2025
Journal Name
European Journal Of Clinical Microbiology & Infectious Diseases
Vibriosis-Associated Acute Kidney Injury: Incidence and Outcome
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Abstract<p><bold>Purpose: </bold>Vibriosis, caused by <italic>Vibrio cholerae</italic>, is an intestinal infection characterized by profuse watery diarrhea, leading to significant fluid loss. This study aimed to assess the clinical features, outcomes, and severity of cholera among hospitalized patients and its association with acute kidney injury (AKI). <bold>Methods</bold>: A prospective cohort study was conducted on 70 patients with confirmed <italic>V. cholerae</italic> infection at Baghdad Teaching Hospital, Medical City, during the cholera outbreak in Iraq (June–October 2022). Patients were recruited from the emergency department and medical quarantine ward. Diagnosis was based on clinical features and confir</p> ... Show More
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Publication Date
Wed Oct 07 2026
Journal Name
Journal Of Engineering
Aerodynamic Characteristics Comparison between Spiroid and Blended Winglets
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A numerical and experimentally investigation for two types of winglets (spiroid and blended), which are used to reduce the induced drag caused by the trailing vortices were presented and discussed in this work. The SOLIDWORK 2016 was used to model a rectangular wing geometry of NACA2415 cross-sectional airfoil with blended and spiroid airfoils (2415 and 0012). The steady, incompressible N.S equations with standard (

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Publication Date
Wed Dec 30 2020
Journal Name
Al-kindy College Medical Journal
Association between gallbladder diseases and Helicobacter pylori infection
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Background: Helicobacter pylorus is one of the most harmful human pathogens & carcinogen. Of the world's population, more than 50% has H. pylori in their upper gastrointestinal tracts. It has been linked to a variety of extra gastric disorders. In correlation to hepatobiliary diseases; recently, the bacterium has been implicated as a risk factor for various diseases ranging from chronic cholecystitis and primary biliary sclerosing cholangitis to gall bladder cancer and primary hepatic carcinomas. However, the association between Helicobacter pylori (H. pylori) and gallbladder diseases is still vague and is controversial.

Aim of study: To elucidate the association of H pylori and gallbladder diseases (calculu

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Publication Date
Sun Feb 03 2019
Journal Name
Journal Of The College Of Education For Women
Relatives marriage and its genetic effect on children
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Marriage is a characteristic of the human race, as it is one of the oldest organization, asoldas human beign marrige is a legitimale relationsbip between male and female in the name of Allah "o mankind !Be dutiful to your lord, Who created you from a single person (Adam), and from him (Adam) He created his Wife (Eve), and from them both He created mang men and women
Marriage is a requirement of human life to ensure tle continuity and survival of the human species and established it in a legal, social and legitimate frame,according to certain criteria and conditions so that the individual earns psychological and social comfort in the name of Allah and Allah has made for you Azwaj ( mates or wives), sons and grand sons, and has bestowed

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Publication Date
Sun Jun 01 2014
Journal Name
Baghdad Science Journal
On Min - Cs Modules and Some Related Concepts
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Our aim in this paper is to study the relationships between min-cs modules and some other known generalizations of cs-modules such as ECS-modules, P-extending modules and n-extending modules. Also we introduce and study the relationships between direct sum of mic-cs modules and mc-injectivity.

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