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Bioequivalence of Two Formulations of Amoxicillin in Human Healthy Volunteers on (HPLC) Technique
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Amoxicillin is commercially available in the form of capsules and tablets containing 250mg or 500mg for oral administration. It is also available in the form of suspension containing "25mg/ml” . Amoxicillin is presently used as the most common antibiotics .Ten healthy Human volunteers were characterized respected to their pharmacokinetic and bioavailability of two formulations of Amoxicillin from two sources of  industrial companies  after a single dose administration was given orally. A procedure is described for determination the concentration levels of Amoxicillin in human plasma of healthy volunteers using high performance liquid chromatography (HPLC) with reversed-phase isocratic column at low wave length of UV-visible detection "230nm". An efficient drug extraction procedure was used for the separation of Amoxicillin after simple extraction with cold methanol using ODS-C18-DB column. The pharmacokinetic 500mg of Amoxicillin capsule orally administrated treatment through 10 hours  has been examined.  The  Amoxicillin  was eluted  for "10.0 minutes" at flow Rate "1.5ml/min." and Temperature equal to 298 K .The retention time of Amoxicillin was observed at 7.0 minutes. The mean absolute recovery of Amoxicillin in blood plasma of all healthy volunteers were 94.1% at 1.0ppm, 102% at 5.0ppm, 103% at 10.0ppm 102% at 20ppm, 99.3% at 40ppm and 104% at 50ppm respectively. The assay showed excellent relationships between area under the curve ratios and drug concentration levels (P>0.002) .Oral Amoxicillin administration in ten healthy volunteers gave maximum concentration peak plasma at two hours and decline through ten hours. Treatment with Iraqi formulation Amoxicillin produced higher area under the curve “AUC” and maximum concentration “C (max)” of Amoxicillin than Indian formulation.

Key word: Amoxicillin, Bioequivalence, ODS -DB column.

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Publication Date
Sun Jan 02 2011
Journal Name
Al-khwarizmi Engineering Journal
Biomechanical Concept Design of Artificial Human Hand
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This work is focused on the design parameters and activity of artificial human finger for seven grips. At first, obtained the ideal kinematics of human fingers motion by analyzing the grips video which were recorded using a single digital camera recorder fitted on a tripod in sagital plane while the hand is moving. Special motion analysis software (Dartfish) the finger joint angles were studied using the video recording. Then the seven grips were modeled using static torque analysis, which calculates the amount of torque applied on the fingers joint grip depending on the results of the kinematic analysis. The last step of the work was to design the actuator (Muscle Wire) of artificial finger for the seven grips in a simple design approac

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Publication Date
Mon Jan 08 2024
Journal Name
Al-academy
The art of sculpting human faces (Portrait)
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It has mixed views on the concept or the role (Portrait) carving human faces across historical periods. The counting and historical document recording profiles for individual, promised impression represents promised impression represents the importance and greatness of personal without attention logs features and individual features, and in all cases the (portrait) was working for celebrated personality, glorifying and out of respect for his role heroic or reputation or social status.
But if we intend carving human faces one varieties of art in sculpture became necessary for us to proceed from the statement which affirms "The requirement of art to be liberated from their recovery forms as they are in the outside world" and here we beg

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Publication Date
Tue May 28 2019
Journal Name
Al-khwarizmi Engineering Journal
Heuristic D* Algorithm Based on Particle Swarm Optimization for Path Planning of Two-Link Robot Arm in Dynamic Environment
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 Finding a path solution in a dynamic environment represents a challenge for the robotics researchers, furthermore, it is the main issue for autonomous robots and manipulators since nowadays the world is looking forward to this challenge. The collision free path for robot in an environment with moving obstacles such as different objects, humans, animals or other robots is considered as an actual problem that needs to be solved.  In addition, the local minima and sharp edges are the most common problems in all path planning algorithms. The main objective of this work is to overcome these problems by demonstrating the robot path planning and obstacle avoidance using D star (D*) algorithm based on Particle Swarm Optimization (PSO)

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Publication Date
Sat Apr 15 2023
Journal Name
Iraqi Journal Of Science
Ecological observations on two species of Gastropoda (Family Hygromiidae) : Monacha cantiana and Candidula gigaxii In three central Iraq provinces
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This study was carried out on two species of the Hygromiidae family Monacha
cantiana and Candidula gigaxii collected from six sites in three central Iraq
provinces (Baghdad , Babylon and Karbala) . A total of 1318 individuals of Monacha
cantiana and 173 of Candidula gigaxii have been examined during the study period
from October 2013 to July 2014.The study included estimation of species relative
abundance, population density and relationship with some physico- chemical
properties of the soil; temperature, moisture and pH.
The Monacha cantiana was present at all sites but with varying numbers, while
Candidula gigaxii was confined to only three sites: Aljadiriyah and Zafaraniya at
Baghdad, and Hindiya dam at Baby

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Publication Date
Sat Jun 30 2012
Journal Name
Al-kindy College Medical Journal
Correlation of Concentrations of Certain Trace Elements in Normal and Diseased Human Tissues
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Background Over the past decade there has been a growing awareness of, and interest in, the trace element concentration differences between normal and diseased tissues. Significant changes in tissue concentrations of Zinc (Zn) and Copper (Cu) have been previously reported in inflammation and cancer of certain human tissues.
Aim:(1)To correlate between Zn and Cu concentrations and the histological picture of normal and certain inflamed human tissues, namely the gall bladder (GB) the vermiform appendix (VA), visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT). (2) to detect whether there is a difference in the above-mentioned parameters between VAT and SAT. (3) to obtain recordings for trace element levels in human tissu

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Publication Date
Sat Feb 01 2020
Journal Name
Journal Of Economics And Administrative Sciences
The role of the strategic mind of human resources managers in strategic drift
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Abstract

The research aims to identify the role played by the strategic mind of human resources managers in reducing the levels of strategic drift that can face the organization, as the problem of research to overlook the importance of this role in monitoring and follow-up all the changes that may face the organization during the implementation of its strategy, therefore highlights the importance Research in providing a set of solutions to the problems faced by the researched organization and as far as the research variables, the researchers have adopted the descriptive analytical approach in the applied side, as adopted the questionnaire as a main tool for data collection, which was prepared based on a number of ready me

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Publication Date
Fri Jun 28 2024
Journal Name
Curr Pharm Des
Synthesis, Characterization, and Antimicrobial Evaluation of Schiff base-mixed Ligand Complexes with Divalent Metal Ions Derived from Amoxicillin and Vanillin/Nicotinamide
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Publication Date
Thu Sep 29 2022
Journal Name
World Journal Of Clinical Infectious Diseases
Five-year retrospective hospital-based study on epidemiological data regarding human leishmaniasis in West Kordofan state, Sudan
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Publication Date
Sun Apr 09 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Identification of Enterococcus faecalis Isolated from Infected Human Tooth Root Canals Human by Using Polymerase Chain Reaction
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     One hundred samples of root canal bacteria were isolated  from patients teeth with primary and secondary infected root canal from all the ages . Biochemical and microscopial tests were done for identification of these isolates. Twenty four isolates were confirmed as       E. faecalis species by using these tests. Genetic diagnosis for the all isolates was also done by using polymerase chain reaction ( PCR ). Thirty two isolates were confirmed to  belong to E. faecalis species by using this test.

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Publication Date
Wed Aug 31 2022
Journal Name
Iraqi Journal Of Science
Estimation of Uranium Concentration in Urine Samples of Three Age Groups of Healthy Individuals in Najaf Governorate Using CR-39 and LR-115 Solid State Detectors
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      Uranium concentration was estimated in urine samples of three age groups, G1≤ 30 years, n=28, G2 age range of 31-40 years, n=28, and G3 of age > 40 years, n=32, using two types of detectors CR-39 and LR-115 solid-state nuclear track detector (SSNTD) for results comparison.

     Results showed that uranium mean level values for CR-39 were 1.961 ±0.08 µg/L, 1.810 ±0.09 µg/L and 1.814 ±0.076 µg/L for G1, G2 and G3 respectively, while the mean values of uranium concentration using LR-115 were 0.972 ±0.07 µg/L, 0.922 ±0.07 µg/L and 1.018 ±0.08 µg/L in G1, G2 and G3 respectively, with significant statistical difference betw

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