Preferred Language
Articles
/
bijps-357
Effect of Metformin Treatment on some Blood Biomarkers in Women with Endometriosis.
...Show More Authors

 Endometriosis is a common women health disorder that occurs when Endometrial-like tissue grows outside the uterus. This may lead to irregular bleeding , pelvic pain, infertility and other complications.   Metformin,  because of its activity to improve  insulin sensitivity, it is  used for  the treatment of diabetes; it  also  has a modulatory  effect  on  ovarian  steroid  production and has  anti-inflammatory  properties,  all may  suggest  its possible effect in treatment  of endometriosis. This  study  was  planned  to  determine  the  effect  of  metformin  on serum levels  of  interleukin- eight(IL-8),  Tumor  necrosis  factor-alpha (TNF –α)  and estradiol (E2)  production , and  related  symptomatic  changes  that  accompany  with endometriosis  (pelvic  pain,  dysmenorrhea  and  menorrheaga)  after  three months of study. Blood samples were obtained from those taking  metformin and measure the serum levels of (IL-8) , TNF –α and (E2) were measured before and after three months of taking a  metformin .Metformin  therapy  resulted  in  a  significant  reduction  in  the  clinical symptoms  of  endometriosis  (pelvic  pain  and  dysmenorrhea)  and insignificant changes in menorrhagia. Metformin therapy resulted in a  significant  reduction  in the serum levels of  IL-8,  TNF-  α while  insignificant  reduction  in  estradiol  E 2  in  the  study  group after 3 months of treatment .In conclusion the results of this study, demonstrated that metformin may be a well-tolerated  treatment  for  endometriosis  that  relieved  pain  and reduces  menstrual disorders and serum  levels  of  the  inflammatory  markers  (IL-8  and  TNF-α)  are decreased  in study  group treated  with metformin after 3 months due to its   anti-  inflammatory effects.

Keywords: Endometriosis, Metformin, TNF – a ,IL-8, E 2.

Crossref
View Publication Preview PDF
Quick Preview PDF
Publication Date
Mon Feb 01 2021
Journal Name
Annals Of Fuzzy Mathematics And Informatics
Topology of cubic bipolar structures and its application on Q-algebra
...Show More Authors

In this paper, we define a cubic bipolar subalgebra, $BCK$-ideal and $Q$-ideal of a $Q$-algebra, and obtain some of their properties and give some examples. Also we define a cubic bipolar fuzzy point, cubic bipolar fuzzy topology, cubic bipolar fuzzy base and for each concept obtained some of its properties.

Publication Date
Sun May 28 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Science
On-Line Navigational Problem of a Mobile Robot Using Genetic Algorithm
...Show More Authors

Publication Date
Sun Jun 18 2023
Journal Name
International Journal Of Development In Social Sciences And Humanities
A CRITICAL DISCOURSE ANALYSIS OF SELECTED POLITICAL SPEECH ON ONLINE EDUCATION
...Show More Authors

PDBN Rashid, International Journal of Development in Social Sciences and Humanities, 2023

View Publication
Publication Date
Fri Jan 01 2021
Journal Name
Aip Conference Proceedings
The effects of devitrification on the lithium glass surface and microstructure
...Show More Authors

View Publication
Scopus Crossref
Publication Date
Sun Sep 30 2012
Journal Name
College Of Islamic Sciences
The Authority and its impact on the prevention of Sharia rulings
...Show More Authors

Praise be to God, Lord of the worlds, and prayers and peace be upon our master Muhammad and upon his family and companions.
And after:

      Muslim scholars have fought in the extent of regard to these interests, each according to his opinion and according to his evaluation, and his consideration of this interest, but it remains important that the legislation in them needs more precaution and caution against the predominance of passions, because the passions often decorate spoilers so they see an interest, so practical application must To realize the spirit of Islamic Sharia in its entirety of its rulings, and the preponderance between the interests and evils that prevail in our societies, which c

... Show More
View Publication Preview PDF
Publication Date
Thu Aug 03 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Acute Effective of Chromiume on the Simocephalus expinosus and Mesocyclops hyalinus
...Show More Authors

          The effect of acute toxicity of chromium as (k2Cro4) on Simocephalus  expinosus (cladocera) and Mesocyclops hyalinus (cyclopoida) was studied in the present study .Both species can be used as asutible biological indecaters. In addition  Both of them are part of crustacean zooplankton.Their position in the fresh water  food chain, as the cladocerans constitutes the primary consumers while cyclopoids are part of secondary consumers.         To determine LC50 of chromium for the two species the following concentrations  of chromium  were  used 1,2, 3,4, 5,6, 14,18, 22,26,28, and 30 ppm. The results showed that LC 50 o

... Show More
View Publication Preview PDF
Publication Date
Tue May 23 2023
Journal Name
Journal Of Engineering
Injection Temperature Effects on the Properties of High Density Polyethylene Crates
...Show More Authors

This study was undertaken to provide more insight on the optimum injection temperature used for the production of PE crates, thereby saving time and money, and improving part quality. The work included processing trails of HDPE crates in an injection
molding machine at five temperatures ranged from 220 to 300°C. Both Rheological and mechanical characterization was conducted in order to understand the effect of injection temperature on the properties of crates. Oven aging was also applied for (4 weeks) to evaluate the long-term thermal stability. The results revealed that producing the crates at a temperature range of (260-280 °C) gives the best rheological and mechanical result. The lowest drop in thermal stability has been observed

... Show More
View Publication Preview PDF
Crossref
Publication Date
Mon Jan 01 2024
Journal Name
Journal Of Engineering
Experimental Investigation about the Effects of Blockage on Upstream Box Culverts
...Show More Authors

This experimental study focuses on scouring in box culvert inlets under steady-state conditions and at different percentages of blockage ranging from 0% to 65%, and also looks at the hydraulics of water in the culvert. The investigation shows that the blockage of the culverts has influenced the scouring pattern at the blocked culverts' entrances. Ten experiments were carried out at the laboratory to see how blockage impacts the scouring pattern upstream of a box culvert during steady flow. Both partially blocked and unblocked cases were implemented in this study. The experimental tests were done until the equilibrium scour occurred, which took about 3.5 hours of water flow to reach equilibrium conditions.  The results r

... Show More
View Publication Preview PDF
Crossref (1)
Crossref
Publication Date
Sun Jan 01 2023
Journal Name
Revista Iberoamericana De PsicologĂ­a Del Ejercicio Y El Deporte
THE PSYCHOLOGICAL EFFECTS OF PERFECTIONISM ON SPORT, ECONOMIC AND ENGINEERING STUDENTS
...Show More Authors

Scopus (14)
Scopus
Publication Date
Sun Jun 30 2019
Journal Name
Iraqi Journal Of Chemical And Petroleum Engineering
Adsorption of Chromium Ions on Activated Carbon Produced from Cow Bones
...Show More Authors

Due to the broad range uses of chromium for industrial purposes, besides its carcinogenic effect, an efficient, cost effective removal method should be obtained. In this study, cow bones as a cheap raw material were utilized to produce active carbon (CBAC) by physiochemical activation, which was characterized using: SEM to investigate surface morphology and BET to estimate the specific surface area. The best surface area of CBAC was 595.9 m2/gm which was prepared at 600 C activation temperature and impregnation ratio of 1:1.5. CBAC was used in aqueous chromium ions adsorption. The investigated factors and their ranges are: initial concentration (10-50 mg/L), adsorption time (30-300 min), temperature (20-50

... Show More
View Publication Preview PDF
Crossref (8)
Crossref