Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a potent ligand for AhR and a known carcinogen. While AhR activation by TCDD leads to significant immunosuppression, how this translates into carcinogenic signal is unclear. Recently, we demonstrated that activation of AhR by TCDD in naïve C57BL6 mice leads to massive induction of myeloid derived-suppressor cells (MDSCs). In the current study, we investigated the role of the gut microbiota in TCDD-mediated MDSC induction. TCDD caused significant alterations in the gut microbiome, such as increases in Prevotella and Lactobacillus, while decreasing Sutterella and Bacteroides. Fecal transplants from TCDD-treated

Breast cancer is the most common malignancy affecting women's health, with an increasing incidence worldwide. This study aimed to measure the intracellular concentration of the hypoxia-inducible factor 1 α (HIF-1α), tumor suppression protein p53, and estradiol (E2) in tumor tissues of adult females with breast cancer and their relation to tumor grade, tumor size, and lymph node metastases (LNM). The study was conducted on 65 adult female participants with breast mass admitted to the operating theater in Al-Hussein Teaching Hospital and Al-Habboby Teaching Hospital in Nasiriyah, Iraq, from January to November 2021. Fresh breast tumor tissues were collated and homogenized for intracellular biochemical analysis using the enzyme-linked immuno

Chapter One – introduction

Nations managed today to achieve progress in the field of modern technology. Science has changed many beliefs and trendiness that people have held for long time, skills and scientific thinking developed, and made scientific observation  and experiment replace narration and taking from others. That is attributed to examining  the educational systems searching for the locations of defect, and shortage.

In the light of educational modernizations, many models of teaching incliuding a model for social tracing attributed to Herbart Thelen, which is a model to develop skills of social participation in the democratic process (Al-Khawalda,1993,335).

   يتناول البحث جمع توجيه العلامة علي النوري الصفاقسي للقراءات، الذي ضمّنه في كتابه (غيث النفع في القراءات السبع) وإفراده في بحث مستقل، والتعليق على ما يحتاج لتعليق وبيان من توجيهه، ويتكون من مقدمة

للدراسات التاريخية أهميتها ولاسيما دراسة المؤلفات الذي يعطينا صورة كاملة عن تطور الواقع التاريخي للمرحلة التي عاصرها المؤلف وتكتب دراسة الشخصيات العلمية طابعاً خاصاً ومهم يدفعنا إلى التعريف بالمؤرخ ومنهجه في الكتاب والموارد التي استقى معلوماتهِ منها . 

The research revolves around the methodology of the historian Ibn Wasil
(d.697 AH) in dealing with the Mongolian invasion through his book
“Mafrej al-Karroub fi Akhbar Bani Ayyub

هدف هذا البحث الى التعرف على أثر فاعلية تكنولوجيا التحول الرقمي في تحسين كفاءة الخدمة التأمينية في شركات التأمين العامة في العراق من خالل تكنولوجيا التحول الرقمي في العملية التأمينية "الترويج لمنتج التأمين,تقديم طلب التأمين,االكتتاب ,تسوية الخسائر" ولتحقيق هذا الهدف تم تصميم استمارة استقصاء وزعت في المجتمع المبحوث والتي تمثل متخذي القرار في الشركات المبحوثة قيد البحث وكان من اهم نتائج البحث وجود عالقة بين ا