Preferred Language
Articles
/
WhdkoZIBVTCNdQwCm7uK
Berbamine and thymoquinone exert protective effects against immune-mediated liver injury via NF-κB dependent pathway
...Show More Authors
Background

Immune-mediated hepatitis is a severe impendence to human health, and no effective treatment is currently available. Therefore, new, safe, low-cost therapies are desperately required. Berbamine (BE), a natural substance obtained primarily from Berberis vulgaris L, is a traditional herbal medicine with several bioactivities, such as antimicrobial and anticancer activities. Thymoquinone (TQ), a phytochemical molecule derived from the Nigella sativa plant's black cumin seeds, has attracted interest owing to itsanti-inflammatory, antioxidant, and anticancer properties.

Aim

This current study's aims was to examine the protective impacts of BE and TQ in Concanavalin A (ConA)- induced acute liver injury and the action's underlying mechanism.

Methods

sixty mice of both sexes were used and divided into four groups (each group with six mice) as follows: Group I obtained distilled water (negative control group). Group II received distilled water with a single dose of 0.1 ml ConA (20 mg/kg) on day 4 by retro-orbital route (model group). Groups III and IV received BE (30 mg/kg/day) and TQ (25 mg/kg/day), respectively, by oral gavage for four successive days, with a single dose of ConA (20 mg/kg) on day 4, then all animals were sacrificed after 8 h and prepared for liver and blood collection.

Results

ConA administration increased the ALT, AST, TNF-α, INFγ, and NF-κB significantly (p < 0.001) in the model group. Both BE and TQ could reduce these parameters significantly (p < 0.001) in groups III and IV, respectively, compared to the model group.

Conclusion

Both BE and TQ prominently attenuated ConA immune-mediated liver injury. These findings give a remarkable insight into developing a new therapeutic agent for treating hepatitis and other autoimmune diseases.

Scopus Clarivate Crossref
View Publication
Publication Date
Fri Dec 08 2023
Journal Name
Iraqi Journal Of Science
A Modified Hestenes-Stiefel Conjugate Gradient Method and its Global convergence for unconstrained optimization
...Show More Authors

In this paper, we proposed a modified Hestenes-Stiefel (HS) conjugate
gradient method. This achieves a high order accuracy in approximating the second
order curvature information of the objective function by utilizing the modified
secant condition which is proposed by Babaie-Kafaki [1], also we derive a nonquadratic
conjugate gradient model. The important property of the suggestion
method that is satisfy the descent property and global convergence independent of
the accuracy of the line search. In addition, we prove the global convergence under
some suitable conditions, and we reported the numerical results under these
conditions.

View Publication Preview PDF
Publication Date
Thu May 04 2017
Journal Name
Ibn Al-haitham Journal For Pure And Applied Sciences
Estimation of The Components of Phenotypic Variance and Heritability in Barley ( Hordeum Vulgar L. )
...Show More Authors

Four genetic populations ( P1 , P2 , F1 , F2) were used in this study .
The parental cross in barley ( P1 barakq and P2 Pakistan ) was done . Many quantitative
pheno types were estimated such as plants length , tillers number , grains yield , capsules
number , the number of grains per capsule and the weight of 1000 grains . The results showed
significant differences in genetic variance values in the seconed filial generation ( F2) for all
the studied phenotypes : High values for the heritability were observed for all the studied
phenotypes .
These results indicated the effect of additive and non-additive genes on the quantitative
phenotypes . Finally , the selection of first generation can utilized for impro

... Show More
View Publication Preview PDF
Publication Date
Sun Feb 10 2019
Journal Name
Journal Of The College Of Education For Women
The Foreignized Translation: One Approach to Respect and Preserve the Culture of the other
...Show More Authors

Domesticated translation has been for a long time the norm in cultural communication between nations all over the world. The texts are translated mainly into English (being the dominant language) in terms dictated principally by the requirements of the target language (English). The claim has been that fluency, readability, and immediate intelligibility can be guaranteed as far as the reader of the target language is concerned (English). The foreignness of the text (of the culture which produced it) would be not preserved. Not only this. Being the language of predominant cultures, English has become number one among languages into which texts are translated. The imbalance has been noticeable between the volumes of works translated from a

... Show More
View Publication Preview PDF
Publication Date
Sun May 30 2021
Journal Name
Iraqi Journal Of Science
An Emerging Fault Related Fold (Mahad Anticline) and its Morphotectonic Interpretations in Northern Iraq
...Show More Authors

In this study, morphotectonic analyses were prepared for an anticline existing to the north of Maqloub Anticline and extends toward north - south approximately, which is unfamiliar in relation to the major extension of the anticlines in the region. The study involves a structural interpretation of the anticline's origin and its relation with the faulting in the foreland zone in this area, specifically in foothill zone, because of the major fracture that is found adjacent and parallel to the axis of this anticline.

The visual interpretation is the major tool used to determine the features of this anticline. Moreover, some facilitating remote sensing technologies, such as digital processing of satellite images and Digital Elevation

... Show More
View Publication Preview PDF
Scopus (1)
Crossref (1)
Scopus Crossref
Publication Date
Fri Dec 30 2022
Journal Name
Iraqi Journal Of Science
Natural Radioactivity and its Hazards of Infracambrian Rocks at Jabal Sanam Structure, Southern Iraq
...Show More Authors

The Jabal Sanam, a piercement salt plug, represents a unique geological phenomenon in southern Iraq. It is a remarkable geological landmark that rises about 141 m above sea level and covers approximately 2 km2, surrounded by flat areas on all sides. A radiological survey was conducted on the Jabal Sanam structure to determine the natural radioactivity levels and related radiation hazard indices. Eleven different rock types from several locations at Jabal Sanam were collected. An optical microscope and X-ray diffraction (XRD) were used to examine and identify the variable rock types in this structure. Natural radioactivity using field and laboratory equipment for these rocks was measured. The findings indicated that the average

... Show More
View Publication Preview PDF
Scopus Crossref
Publication Date
Tue Feb 14 2023
Journal Name
Journal Of Educational And Psychological Researches
Mental Health and Its Role in Enhancing Self-Confidence Positive Behavior among University Students
...Show More Authors

Abstract
The current research aims to identify mental health and its role in promoting self-confidence and positive behavior of female university students. The researcher adopted the descriptive analytical approach in this research. The researcher depended on the availability of sources and references, literature, and previous field studies to analyze and study all aspects related to mental health and its role in promoting self-confidence and positive behavior of university students and then expand its importance and identify the areas of mental health, self-confidence, positive behavior, and university. The second chapter included the concept of mental health, the importance of the study, the most important factors of health and psyc

... Show More
View Publication Preview PDF
Publication Date
Tue Jan 18 2022
Journal Name
Special Care In Dentistry
Association between self‐reported oral disease/conditions and symptoms of depression among Iraqi individuals
...Show More Authors
Abstract<sec><title>Aims

The negative impact of oral diseases on the function, economy, and general health of the population is well‐documented. In the last decades, evidence linking increased expression of depression and oral diseases/conditions has significantly increased. The aim of this study is to assess the association between oral disease/conditions and self‐reported symptoms of depression individuals.

Methods

A specially designed questionnaire was distributed via social media for 1 week. It consisted of two main sections; the first section was dedicated to collect demographic variables and self‐reported symptoms

... Show More
View Publication
Scopus (1)
Crossref (2)
Scopus Clarivate Crossref
Publication Date
Sun Oct 01 2023
Journal Name
Minerva Dental And Oral Science
Salivary interleukin-1β as a biomarker to differentiate between periodontal health, gingivitis, and periodontitis
...Show More Authors

View Publication
Scopus (1)
Crossref (1)
Scopus Clarivate Crossref
Publication Date
Sat Aug 01 2020
Journal Name
Journal Of Constructional Steel Research
Demountable steel-concrete composite beam with full-interaction and low degree of shear connection
...Show More Authors

It is suitable to use precast steel-concrete composite beams to quickly assemble a bridge or a building, particularly in isolated regions where cast-in-situ concrete is not a practical option. If steel-concrete composite beams are designed to allow demountability, they can also be extremely useful in the aftermath of natural disasters, such as earthquakes or flooding, to replace damaged infrastructure. Furthermore, rapid replacement of slabs is extremely beneficial in case of severe deterioration due to long-term stressors such as fatigue or corrosion. The only way to rapidly assemble and disassemble a steel-concrete composite structure is to use demountable shear connectors to connect/disconnect the steel beams to/from the concrete slab. I

... Show More
View Publication
Scopus (33)
Crossref (26)
Scopus Clarivate Crossref
Publication Date
Mon Aug 01 2022
Journal Name
Journal Of Structural Engineering
Standard Pushout Tests and Design Rules for a Bolted–Welded Hybrid Demountable Shear Connector
...Show More Authors

A bolted–welded hybrid demountable shear connector for use in deconstructable steel–concrete composite buildings and bridges was proposed. The hybrid connector consisted of a partially threaded stud, which was welded on the flange of a steel section, and a machined steel tube with compatible geometry, which was bolted on the stud. Four standard pushout tests according to Eurocode 4 were carried out to assess the shear performance of the hybrid connector. The experimental results show that the initial stiffness, shear resistance, and slip capacity of the proposed connector were higher than those of traditional welded studs. The hybrid connector was a ductile connector, according to Eurocode 4, with slip capacity higher than 6 mm. A nonli

... Show More
View Publication
Scopus (10)
Crossref (7)
Scopus Clarivate Crossref