Preferred Language
Articles
/
Vhdsi5IBVTCNdQwCgrTl
Phytochemical constituents of ethyl acetate fraction of both roots and leaves of Sansevieria triafasciata cultivated in Iraq and assessment of its anti-proliferative effect on breast cancer cell line
...Show More Authors

Scopus Clarivate Crossref
View Publication
Publication Date
Thu Dec 23 2021
Journal Name
Iraqi Journal Of Science
The Effect of Climate Changes on The Fluctuation of The Water Level of Al- Razzaza Lake, Iraq
...Show More Authors

      One of the serious environmental challenges that Iraq faces is climate changes and impacts of changing weather patterns and extreme global weather events. This paper addresses changes in the temporal and spatial characteristics of water levels of Razzaza Lake and response to climatic changes using archived series of Multispectral satellite images Landsat. TM, ETM+ and OLI images acquired on 1990, 2000 and of 2016. In order to extract, mapping the water surface area of the Razzaza Lake, Multispectral spectral band rationing the Normalized Difference Water Index (NDWI) technique was adopted, and the climatic elements data for the period (1990-2016) were analyzed which provide significant information of surfac

... Show More
View Publication Preview PDF
Scopus (3)
Crossref (1)
Scopus Crossref
Publication Date
Mon Oct 25 2021
Journal Name
Iraqi Journal Of Science
Detection of Active Compounds in the Water Extract of Foeniculum Vulgare L. and Its Effects on Serum Estrogen and Prolactin Levels in Female Albino Rats
...Show More Authors

      The present study was designed to estimate the active ingredients in the aqueous extract of fennel Foeniculum vulgare L. fruits and test the effects of different concentrations of the extract on serum estrogen and prolactin levels in female rats.  The work was conducted to prepare the aqueous extract in the laboratory, while the secondary active substances in the extract were estimated using High-Performance Liquid Chromatography (HPLC) technology. The experiments were conducted in the animal house of the College of Science, Tikrit university,on a total of 12 adult albino virgin female rats divided into four groups, each having three rats.The aqueous extract of the fruit plant was administrate

... Show More
View Publication Preview PDF
Scopus (1)
Scopus Crossref
Publication Date
Thu Aug 01 2019
Journal Name
Int J Mol Cell Med
Caspase Dependent and Independent Anti-hematological Malignancy Activity of AMHA1 Attenuated Newcastle Disease Virus
...Show More Authors

Hematological malignancies remain one of the leading causes of death worldwide despite advances in cancer therapeutics. Newcastle disease virus (NDV) is a member of Paramyxoviridae that elicits considerable interest as an anticancer agent because it can replicate up to 10 000 times faster in human cancer cells than in most normal cancer cells. Several NDV strains reportedly induce the cytolysis of cancerous cell lines. The attenuated Iraqi strain (AMHA1) of NDV is a novel oncolytic agent with promising antitumor characteristics, including apoptosis induction. This study aimed to evaluate the ability of the AMHA1 NDV strain to induce apoptotic cell death in hematological tumors through caspase-dependent or independent apoptotic pathways. The

... Show More
Publication Date
Wed Mar 24 2021
Journal Name
Indian Journal Of Forensic Medicine & Toxicology
Evaluating the anti- Pseudomonas Aeroginosa Efficacy and Potential Cytotoxicity of Nerium Oleander Alcoholic Extract
...Show More Authors

Nerium oleander known as oleander has belonged to the poisonous plants its habitat in a tropical andsubtropical region. The chemical analysis with GC-Mass of the alcoholic extract of oleander leaves revealedthat this plant has many chemical compounds more than 80 compounds and high-peaks about 29 compoundswhich are represented by alkaloids, phenol, terpenes, and fatty acid. HPLC analysis showed many essentialoils that have many biological effects.To evaluate the antibacterial activity of the alcoholic extract of N. oleander against locally isolatedPseudomonas aeroginosa the broth micro-dilution method was adapted to different concentrations werestarted from 3.9 to1000 mg/ml. The results revealed that the alcoholic extract has antiba

... Show More
View Publication
Crossref
Publication Date
Sat May 08 2021
Journal Name
Iraqi Journal Of Science
Synthesis and Identification of Some Imino Chalcone Derivatives with Evaluating their Anti-oxidant Activity
...Show More Authors

This work involves the preparation of high yield iminochalcon compounds (B1-B15)  through two parts. The first part involves the preparation of 2,4-dihydroxy Chalcone (A1-A15) by the condensation of 2,4-dihydroxy acetophenone  with  aryl aldehyde in the presence of sodium hydroxide (40%) as a catalyst. The second part includes the preparation of  iminochalcon from the condensation of p-hydroxy aniline with 2,4-dihydroxy chalcone  derivatives  )A1-A15)  in the presence of some drops of conc. H2SO4. Thin-layer chromatography ((TLC)  was used to control the chemical reaction . These new derivatives were characterized by using FT-IR and  1H-NMR spectroscopy. These synthesized

... Show More
View Publication Preview PDF
Scopus (2)
Scopus Crossref
Publication Date
Sun Apr 02 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Conjugation of Steroidal and Non – Steroidal Anti- Inflammatory Drugs as Possible Mutual Prodrug
...Show More Authors

Prednisolone (SAID) was conjugated with ibuprofen (NSAID) through an amino acid (glycine) as a spacer arm to synthesize the following compound:

Prednisolone – glycine – ibuprofen.

    The method employed consists of converting the carboxylic acid function of (R,S) – ibuprofen – glycine to the highly reactive acid chloride and subsequent reaction with the C21 hydroxyl group of prednisolone. This reactive intermediate was found to react as well with the C17 tertiary hydroxyl group of the steroid to form three compounds and eight diastereomers. These results were confirmed by T.L.C, and the desired compound was separated by column chromatograph

... Show More
View Publication Preview PDF
Crossref
Publication Date
Sat Apr 30 2022
Journal Name
Iraqi Journal Of Science
Impact of Tharthar Arm on the Composition and Diversity of Rotifera in Tigris River North of Baghdad, Iraq
...Show More Authors

      This study was conducted to evaluate the effects of Tharthar Arm on the composition and diversity of Rotifera in Tigris River. Six sampling sites were selected, two on Tharthar Arm and four along the Tigris River, one before the confluence as a control site and the others downstream of the confluence. Seventy-seven species of Rotifera were identified in Tigris, whereas, 60 in the arm. The results showed that low density of Rotifera in Tharthr Arm decreased the density in Tigris from 239812.4 upstream of the confluence to 223315.5 at immediate downstream of the confluence. It also declined the mean values of richness, evenness and Shannon diversity indices from 5.19, 0.69 and 2.14 bit/Ind., before the confluence to 3.97, 0.73 a

... Show More
View Publication Preview PDF
Scopus (4)
Crossref (1)
Scopus Crossref
Publication Date
Mon Aug 01 2011
Journal Name
J Fac Med Baghdad
Overview of breast cancerpatients and their prognostic factors treated in Baghdad teaching hospital/ oncology department in the year 2010
...Show More Authors

Publication Date
Sun Apr 29 2018
Journal Name
Iraqi Journal Of Science
The anti- Leishmaniasis activity of Purified Bacteriocin Staphylococcin and Pyocin Isolated from Staphylococcus aureus and Pseudomonas aeruginosa
...Show More Authors

Tropical illnesses caused by parasites proceed to cause socioeconomic devastation that reverberate worldwide protozoan parasites, like Leishmania. This parasite has an enormous public health problem in many countries. There is a growing requisite for new control methods for many of these illnesses due to the increasing drug resistance showed by the parasites and problems with drug poisonousness. In this study, fifty-five patients (burns and wounds) were collected from patients from Al-Yarmouk Hospital and Teaching Baghdad Hospital during the period from November, 2015 to January, 2016. Cultural and morphological characteristic examination, biochemical tests were conducted and confirmed the diagnosis by antibiotics sensitivity te

... Show More
View Publication Preview PDF
Publication Date
Thu Mar 30 2017
Journal Name
Iraqi Journal Of Pharmaceutical Sciences ( P-issn 1683 - 3597 E-issn 2521 - 3512)
Synthesis and Preliminary Pharmacological Study of Sulfonamide Conjugates with Ibuprofen and Indomethacin as New Anti-Inflammatory Agents
...Show More Authors

          4-aminobenzenesulfonamide conjugates of ibuprofen (compound 10) and indomethacin (compound 11) have been designed and synthesized by the reaction of sulfanilamide (compound 7) with 2-(4-isobutylphenyl) propanoic acid (ibuprofen) and 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid (indomethacin) for the evaluation as potential anti-inflammatory agents with expected selectivity against COX-2 enzyme. In vivo acute anti-inflammatory activity of the synthesized final compounds (10 and 11) was evaluated in rats using egg-white induced edema model of inflammation in a dose equivalent to (10mg/Kg) of ibuprofen and (2mg/kg) of indomethacin. The tested compounds pr

... Show More
View Publication Preview PDF
Crossref (1)
Crossref